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SUMMARY:Computational Neuroscience Journal Club - Balazs B Ujfalussy (Univ
 ersity of Cambridge)
DTSTART:20131203T160000Z
DTEND:20131203T170000Z
UID:TALK49217@talks.cam.ac.uk
CONTACT:Guillaume Hennequin
DESCRIPTION:Balazs Ujfalussy will cover:\n\nContext-dependent computation 
 by recurrent dynamics in prefrontal cortex\nValerio Mante\, David Sussillo
 \, Krishna V. Shenoy & William T. Newsome\nNature\, 2013\nhttp://www.natur
 e.com/nature/journal/v503/n7474/abs/nature12742.html\n\nPrefrontal cortex 
 is thought to have a fundamental role in flexible\, context-dependent beha
 viour\, but the exact nature of the computations underlying this role rema
 ins largely unknown. In particular\, individual prefrontal neurons often g
 enerate remarkably complex responses that defy deep understanding of their
  contribution to behaviour. Here we study prefrontal cortex activity in ma
 caque monkeys trained to flexibly select and integrate noisy sensory input
 s towards a choice. We find that the observed complexity and functional ro
 les of single neurons are readily understood in the framework of a dynamic
 al process unfolding at the level of the population. The population dynami
 cs can be reproduced by a trained recurrent neural network\, which suggest
 s a previously unknown mechanism for selection and integration of task-rel
 evant inputs. This mechanism indicates that selection and integration are 
 two aspects of a single dynamical process unfolding within the same prefro
 ntal circuits\, and potentially provides a novel\, general framework for u
 nderstanding context-dependent computations.\n
LOCATION:Cambridge University Engineering Department\, CBL Rm #438 (http:/
 /learning.eng.cam.ac.uk/Public/Directions)
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