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SUMMARY:Shaping and reshaping regulatory loops in Drosophila morphogen sig
 naling. - Dr. Giorgos Pyrowolakis from BIOSS Centre for Biological Signall
 ing Studies & Institute for Biology\, University of Freiburg
DTSTART:20140515T133000Z
DTEND:20140515T143000Z
UID:TALK51368@talks.cam.ac.uk
CONTACT:Caroline Newnham
DESCRIPTION:Tight control of intercellular signaling by regulatory feedbac
 k mechanisms is key for proper growth and patterning of tissues and organs
 . I will present our recent efforts towards identifying feedback regulator
 s in Drosophila BMP morphogen signaling and analyzing their impact in the 
 establishment and maintenance of graded signaling. I will then focus on a 
 prominent regulatory feedback loop of the pathway and present mechanisms b
 y which tissue-specific cues might rewire regulatory feedback networks to 
 impact on the shape of morphogen gradients and\, ultimately\, on the shape
  and function of organs.
LOCATION:Part II Room\, Department of Genetics
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