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SUMMARY:Modelling and simulation of cell motility with surface finite elem
 ents - Venkataraman\, C (University of Sussex)
DTSTART:20140319T151500Z
DTEND:20140319T161500Z
UID:TALK51510@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:We propose a general framework for the modelling and simulatio
 n of cell motility. The cell membrane dynamics is governed by a geometric 
 evolution law accounting for its mechanical properties. For the polarisati
 on of the cell we postulate a reaction diffusion system for species locate
 d on the moving cell membrane. Protrusion is than achieved by back-couplin
 g these surface quantities to the geometric equation for the membrane posi
 tion. The numerical method to approximate the general model is based on su
 rface finite elements for both the geometric equation and the surface equa
 tions. We demonstrate the versatility of this approach to describe the mot
 ion of different cells in two and three dimensions. We also discuss the pr
 oblem of fitting to experimental data  and to this end present a method fo
 r identifying parameters in the model.\n
LOCATION:Seminar Room 2\, Newton Institute Gatehouse
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