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SUMMARY:Using metagenomics to identify emerging viral pathogens\, and RNA 
  silencing to combat them - Luke Braidwood\, Baulcombe Lab
DTSTART:20141212T110000Z
DTEND:20141212T113000Z
UID:TALK54597@talks.cam.ac.uk
CONTACT:Megan Cooper
DESCRIPTION:Maize lethal necrosis (MLN) is a synergistic viral maize disea
 se. It has recently spread to South-East Asia and East Africa\, where it r
 epresents a serious threat to a major food crop. The infection is produced
  by the interaction of Maize chlorotic mottle virus (MCMV) and maize-infec
 ting Potyviridae viruses. Both MCMV and the Potyviridae can use a variety 
 of insect vectors to spread between hosts. I am using next generation sequ
 encing to survey the genomic diversity of viruses in East African maize. T
 his sequence data will be used to identify conserved regions of the viral 
 genomes which produce MLN\, and artificial mircroRNAs will be designed to 
 target these regions and inserted into maize. The ultimate aim is to produ
 ce maize varieties with increased resistance to MLN\, thereby improving fo
 od security in East Africa. In addition I am using artificial innoculation
  and molecular methods to investigate the methods of pathogenesis and syne
 rgy between the viruses.\n\n\n1st year graduate seminar
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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