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SUMMARY:Decreasing the oxygenase activity of Rubisco: a synthetic biology 
 approach - Marek Szecowka (Hibberd Lab)
DTSTART:20150226T130000Z
DTEND:20150226T133000Z
UID:TALK56594@talks.cam.ac.uk
CONTACT:Stephanie Swarbreck
DESCRIPTION:Substantial agricultural gains would be possible if the oxygen
 ation of RuBisCO were bypassed. As yet\, attempts at its manipulation have
  not resulted in improved C3 photosynthetic yield. As a part of consortium
  of laboratories in the UK and USA my research focuses on generating synth
 etic protein scaffolds enabling metabolic channeling in plants by tetherin
 g C4 pathway related enzymes in a cell and organelle specific manner. We p
 lan to combine this approach together with expression of novel ion pumps d
 esigned in the collaborating laboratories\, to deliver high concentration 
 of CO2 around RuBisCO. This should enhance the efficiency of carbon fixati
 on in the plant.\n\nComponents of the protein scaffold were successfully e
 xpressed and imported into chloroplasts where they form complexes. As ongo
 ing work I am generating Arabidopsis thaliana lines expressing scaffold an
 d scaffold interacting domains fused with C4 pathway related enzymes in a 
 cell specific manner. 
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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