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SUMMARY:Two Things Evolution Can Tell Us About Metabolic Engineering - Ste
 ven Burgess\, Julian Hibberd Lab
DTSTART:20160114T130000Z
DTEND:20160114T133000Z
UID:TALK63123@talks.cam.ac.uk
CONTACT:Jeongmin Choi
DESCRIPTION:One of the key aims of synthetic biology is to create standard
 ized biological components that can be combined to produce predictable out
 comes. However\, the functionality of components such as promoters can var
 y between species. This represents a significant challenge if one is to av
 oid constructing a separate genetic tool box for each species of interest.
  Examples of convergent evolution of complex traits can be found in nature
 \, the study of which may provide clues to whether the development of a sp
 ecies-independent tool box is a realistic aim. The C4 photosynthetic pathw
 ay is one such example\, it has evolved multiple times and is present in a
 t least 66 independent lineages. This presentation will cover work from th
 e Hibberd lab investigating how cis-regulation of the C4 photosynthetic pa
 thway has evolved\, including data from classic reporter cut-down analysis
  and DNase-Seq\, before reflecting on what can be learned for the purposes
  of metabolic engineering.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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