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SUMMARY:Destiny of retrieved associative memories in vertebrates and inver
 tebrates - Emiliano Merlo (University of Cambridge)
DTSTART:20160617T150000Z
DTEND:20160617T163000Z
UID:TALK65333@talks.cam.ac.uk
CONTACT:Jimena Berni
DESCRIPTION:Even though stored associative memories can last up to the ent
 ire animal’s life\, they are not immutable. Retrieval can trigger two an
 tagonistic memory processes. If retrieval is brief\, the conditioned respo
 nse is maintained through a process known as reconsolidation. On the contr
 ary\, a prolonged reminder will trigger memory extinction and a long-lasti
 ng inhibition of the original conditioned response. Both reconsolidation a
 nd extinction are universally conserved processes present all along the An
 imal Kingdom. Based on behavioural\, pharmacological and molecular data ob
 tained from crabs and rats\, I will discuss the evidence indicating that: 
 1) specific mechanisms support persistence or inhibition of the original m
 emory\, and 2) reconsolidation and extinction are mutually exclusive proce
 sses\, separated by an insensitive or ‘limbo’ period.
LOCATION:Hodgkin Huxley Seminar Room\, Physiology Building\, Department of
  Physiology\, Development and Neuroscience.
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