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SUMMARY:Lattice models for DNA origami self-assembly - Alexander Cumberwor
 th (University of Cambridge)
DTSTART:20161111T120000Z
DTEND:20161111T122000Z
UID:TALK68031@talks.cam.ac.uk
CONTACT:Lisa Masters
DESCRIPTION:DNA origami is a class of highly designable\, self-assembling 
 structures with myriad potential applications in both medical and non-medi
 cal fields. The assembly process of these systems\, which involves the bin
 ding of a number of short staple strands to a longer scaffold strand\, has
  not been fully characterized\, and current models capable of studying the
  process are either computationally intractable or lack important features
 . In this talk\, I will discuss a new class of models for DNA origami we h
 ave been developing that attempt to bridge this gap by representing the sy
 stems on a lattice at the level of binding domains and using simulation me
 thods that allow explicit simulation of free staple strands to be avoided.
LOCATION:Unilever Lecture Theatre\,  Department of Chemistry
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