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SUMMARY:Transcriptional and phenotypic variability in response to temperat
 ure in plants - Dr Sandra Cortijo
DTSTART:20161019T130000Z
DTEND:20161019T140000Z
UID:TALK68307@talks.cam.ac.uk
CONTACT:Emily Boyd
DESCRIPTION:The regulation of gene expression is often noisy rather than\n
 being uniform. Identical cells can oscillate between different\ntranscript
 ional burst states\, such that at any one time they are likely to\nhave qu
 ite different gene expression behaviours. However the mechanisms\nand pote
 ntial biological roles of transcriptional noise are still poorly\nundersto
 od. The widespread nature of this behaviour has lead to propose\nthat tran
 scriptional noise is beneficial under stress conditions. Up to\nnow\, most
  studies on the role of transcriptional noise have been performed\nin unic
 ellular organisms or in cell cultures and little is known about the\nrole 
 of transcriptional noise and how transcriptional noise is controlled\nin a
  multicellular organism. We are analysing transcriptional noise\nbetween c
 ells and between individuals in response to environment using the\nplant m
 odel species Arabidopsis thaliana combining transcriptomic and\nmicroscopy
  approaches.
LOCATION:MR4\, Centre for Mathematical Sciences\, Wilberforce Road\, Cambr
 idge
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