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SUMMARY:Essential head genes in the giant PhiKZ-related phages - Professor
  Julie Thomas\, Rochester Institute of Technology\, Rochester\, United Sta
 tes
DTSTART:20161216T135000Z
DTEND:20161216T143000Z
UID:TALK69676@talks.cam.ac.uk
CONTACT:Ilana Spilka
DESCRIPTION:A “giant” phage has a long genome (>200 kb) and a large\, 
 structurally complex virion.  The head of Salmonella phage SPN3US is compo
 sed of about 50 different proteins. Numbers of these proteins\, including 
 a multi-subunit RNA polymerase (vRNAP)\, are packaged inside the head alon
 g with the 240 kb dsDNA genome and ejected into the host cell.  However\, 
 the functions of the majority of head proteins are unknown.  In this talk 
 I will discuss how our new collection of SPN3US mutants has facilitated id
 entification of essential head genes and novel features of giant phage hea
 d structure\, function and assembly.     
LOCATION:Online
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