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SUMMARY:Crick Lecture-The Surprising Chemistry of Non-enzymatic RNA Replic
 ation - Jack Szostack\, Harvard\, USA 
DTSTART:20170907T150000Z
DTEND:20170907T160000Z
UID:TALK70288@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:The RNA genomes of the first cells are thought to have emerged
  from the nonenzymatic replication of short RNA strands\, which allowed th
 e first ribozymes to evolve\, followed by the evolution of ribozyme cataly
 zed replication. However\, no process for the replication of a nucleic aci
 d genome\, independent of evolved enzymatic machinery\, has yet been descr
 ibed. Dr. Szostak will discuss his laboratory’s recent progress toward t
 he realization of an efficient and accurate system for the chemical replic
 ation of RNA. Mechanistic and structural studies have led to new chemical 
 replication systems that are both more prebiotically plausible and more ac
 curate\, efficient\, and general.
LOCATION:Max Perutz Lecture Theatre\, Medical Research Council (MRC) (MRC 
 Laboratory of Molecular Biol
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