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SUMMARY:Single Cell Seminars (September) - Qianxin Wu (Cell Ops R&D) and V
 alentine Svensson (Teichmann group)
DTSTART:20170929T140000Z
DTEND:20170929T150000Z
UID:TALK71888@talks.cam.ac.uk
CONTACT:Lia Chappell
DESCRIPTION:Please come along to the monthly campus Single Cell Seminar se
 ries. All are welcome\, include colleagues from Cambridge (though email me
  so we can book them in as a visitor with security)\n\n*Speaker 1: Qianxin
  Wu (Cell Ops R&D) _"Targeted single cell transcripts profiling with combi
 natorial indexing (sci-rna-seq)"_*\n\n*Speaker 2: Valentine Svensson (Teic
 hmann group) _"Bioinformatics Journal Club: ZINB-WaVE"_*\n\nQianxin will b
 e giving an update on progress on her work with the sci-rna-seq protocol\,
  which can process thousands of fixed cells in parallel. The bioRxiv manus
 cript was discussed in a previous single cell seminar\, and the protocol h
 as recently been published by the Shendure lab in Science (http://science.
 sciencemag.org/content/357/6352/661).\n\nValentine will be presenting a jo
 urnal club on the ZINB-WaVE manuscript posted on bioRxiv (http://www.biorx
 iv.org/content/early/2017/04/06/125112). The authors claim that ZINB-WaVE 
 provides a "general and flexible method for signal extraction from single-
 cell RNA-seq data"\, that can handle zero inflation (dropouts)\, over-disp
 ersion\, and the count nature of the data. Valentine will explain some of 
 the underlying concepts\, but do look at the paper if you can. \n\n
LOCATION:C302\, Sulston Building\, Wellcome Genome Campus\, Hinxton. CB10 
 1SA
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