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SUMMARY:Cyclic Peptides: Building Blocks for Supramolecular Designs - Prof
 essor Juan R. Granja - University of Santiago de Compostela 
DTSTART:20170822T130000Z
DTEND:20170822T140000Z
UID:TALK75921@talks.cam.ac.uk
CONTACT:Sharon Connor
DESCRIPTION:The ability to construct complex functional materials using a 
 small number of components represents an efficient synthetic strategy for 
 the rapid generation of novel architectures and functions. In this respect
 \, peptides are powerful tools for the preparation of novel nanobiomateria
 ls because of their unique folding and self-assembly properties. Cyclic co
 mponents have restricted conformational freedom adopting kinetically stabl
 e structures that can be implemented in supramolecular applications. In th
 e last few years our research group has been mainly working with disc-shap
 ed cyclic peptides that contain cyclic gamma-amino acids. These peptides a
 llowed the construction of tubular structures of nanometric dimensions wit
 h tunable internal and external properties. Therefore the tubes can be des
 igned for organic\, aqueous or lipidic media allowing their implementation
  in a variety of applications. In addition\, the peptides can be used in t
 he preparation of other architectures\, such as molecular capsules\, spher
 ical clusters and so on. 
LOCATION:Pfizer Lecture Theatre\, Department of Chemistry\, Lensfield Road
 \, Cambridge
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