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SUMMARY:Plant intracellular immune receptors\; diversity\, deployment and 
 dissection - Jonathan Jones\, Sainsbury Lab\, Norwich
DTSTART:20171116T130000Z
DTEND:20171116T140000Z
UID:TALK82471@talks.cam.ac.uk
CONTACT:david baulcombe
DESCRIPTION:Diverse microbes cause plant disease\, and plants have evolved
  a robust innate immune system that recognizes pathogen molecules and then
  activates defense. Immunity involves both cell surface receptors (usually
  transmembrane protein kinases) also intracellular NLR immune receptors\, 
 encoded byResistance (R) genes. Plant NLRs are modular proteins and usuall
 y carry an N-terminal signaling domain\, followed by a nucleotide-binding 
 domain and C-terminal LRRs.  NLRs either directly recognize pathogen effec
 tor molecules\, or recognize the effects of these effectors on host protei
 ns. Plants show extensive within- and between-species diversity in their N
 LR-encoding repertoires\, which we investigate using sequence capture meth
 ods\, and polymorphism in population NLR repertoires is important for thei
 r efficacy.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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