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SUMMARY:Using DNA to Program Nanostructure Assembly and Molecular Machiner
 y - Professor Andrew Turberfield\, University of Oxford\, Department of Ph
 ysics\, Clarendon Laboratory.
DTSTART:20171006T150000Z
DTEND:20171006T160000Z
UID:TALK87011@talks.cam.ac.uk
CONTACT:Lorenzo Di Michele
DESCRIPTION:Nanofabrication by biomolecular self-assembly can be used to c
 reate atomically precise\, nanometre-scale structures. The control offered
  by DNA-self-assembly is spectacular: thousands of oligonucleotides can be
  designed to form rigid\, three-dimensional complexes with defined contour
 s and internal cavities. Each oligonucleotide has a unique sequence which 
 defines its position in these structures\, and chemically modified oligonu
 cleotides can be used to position other molecular components. Synthetic nu
 cleic acids can also form programmable dynamic systems which compute and e
 xhibit complex temporal behaviours. I shall survey this rapidly evolving r
 esearch field and its potential to provide new tools and technologies from
  biophysics to manufacture to medicine\, and describe some of our own work
  on DNA origami assembly pathways and synthetic molecular machinery\, incl
 uding its use to control covalent chemical synthesis.\n
LOCATION:Small Lecture Theatre\, Cavendish Laboratory
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