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SUMMARY:To grow or not to grow - Professor Nicholas Harberd\, University o
 f Oxford
DTSTART:20080313T160000Z
DTEND:20080313T170000Z
UID:TALK9402@talks.cam.ac.uk
CONTACT:3901
DESCRIPTION:The DELLA proteins (DELLAs) are a subfamily of the plant-speci
 fic GRAS family of putative transcriptional regulators that regulate plant
  growth in response to the phytohormone gibberellin (GA). The DELLAs restr
 ain growth\, and GA promotes growth by opposing DELLA function. Essentiall
 y\, GA binds to a specific GA-receptor protein (GID1)\, thus stimulating a
  GID1-DELLA protein-protein interaction. This interaction itself promotes 
 specific targetting of DELLAs for destruction in the proteasome via the SC
 FSLY1 E3 ubiquitin ligase. Additional signalling pathways\, such as those 
 associated with phytohormones other than GA\, and environmental variables 
 such as light\, temperature and nutrient status\, also influence plant gro
 wth via effects on the GA-DELLA growth-regulatory mechanism. The concept t
 hat the DELLAs are integrators of multiple plant growth regulatory signall
 ing inputs will be explored\, and the broader biological significance of D
 ELLA function will be illustrated\, with particular emphasis on the questi
 on of how the GA-DELLA growth-regulatory mechanism arose during land-plant
  evolution.\n\nhttp://www.jic.ac.uk/staff/nicholas-harberd/
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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