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Talks given by

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Talks organised by

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• Tea Club Seminar - Sophien Kamoun “How to trick a plant pathogen”
• Tea Club Seminar - Florian Schmidt "Interrogating Infection and Immunity with Camelid Nanobodies"
• Wes Robertson - Sense codon reassignment in a recoded bacterium enables encoded polymer synthesis
• Gisela Otten - Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection
• Dr Kiran Patil - “What drugs do to our bugs"
• Dr Michael Boemo - Observing DNA Replication on Single Molecules with Nanopore Sequencing and Deep Learning
• Nongenetic mechanisms of tumor evolution and therapy resistance
• Mycobacterial structural biology and prospects for drug development in academia
• CANCELLED Ubiquitin-like modifications and proteasomaldegradation pathways in the Archaea
• Uncovering the role of centrioles and cilia in signal transduction and metabolism
• iRhom pseudoproteases as metabolic regulators
• The fascinating world of nucleic acids. From the origin of life to modern biochemistry
• CANCELLED: Selective inhibition of phosphatases to boost protein quality control : A possible treatment for degenerative diseases
• Prof Tom Thompson - Diversity of receptor signaling mechanisms within the TGFβ family
• Departmental Tea Club Seminar - Preparing for DNA replication: mechanism of eukaryotic replicative helicase loading revealed by cryo-EM
• MDM2 Splicing Control: a rheostat for p53 activity
• Multiomics elucidates transcriptional gene regulation
• Body temperature controlled kinase activity: from rhythmic alternative splicing in mammals to sex determination in reptiles.
• Description:Novel functions of the C-terminal domain of PTCH1: a platform for non-canonical Hedgehog signalling
• Multivalent interactions as a source of specificity and regulation in RNP assembly
• Polarized endosome dynamics during asymmetric cell division
• CANCELLED: Getting in Shape: in vivo and in silico studies of tissue mechanics in growth control
• Horizon’s Adventures in CRISPR land
• Cryo-EM structures of tau filaments from Alzheimer's disease
• Glioblastoma: Tales of Stem Cell Reprogramming and Transdifferentiation
• Prof Catherine Pears - Title tbc
• Contributions of the APC protein to mechanisms regulating normal epithelial tissue organisation in the intestine
• Diversity of Clathrin Function in Membrane Traffic
• Structures, interactions and functions of biofilm-forming proteins from staphylococci
• Unconcious Bias talk
• Prion-mediated control of fungal phenotypes
• Stem cell replacement in intestinal epithelium: why it might matter
• Professor Doug Winton - Title tbc
• Discovery of TAGRISSO: The Next Chapter In The Treatment Of Mutant EGFR NSCLC
• Molecular mechanisms of RNA degradation
• Centrosomal Polo kinase as a key regulator of both cell cycle and morphogenesis
• Functional links between splicing and transcription
• Innate Immunity to Bacterial Infection
• Prof Angus Lammond - Title tbc
• Switches and latches; the control of mitosis
• Prof Reinhard Luermann - Title tbc
• Dr. Tom Owen-Hughes - Title tbc
• Genome scale nucleosome organisation
• Control of smooth muslce contraction by filamin RNA editing
• Generalists and specialists: a new view of how MHC class I molecules protect against disease
• Cell-cell communication in cancer
• A draft map of the mouse pluripotent stem cell spatial proteome
• Prof Deborah Gill - Title tbc
• "Innate Immunity : from Insects"
• Notch Deficiency in the Skin: From Inflammation to Cancer
• Processing the Transcriptome and Epitranscriptome: Message Ends
• "Did we break it?'; a structural biologist's view of the Smc-5/6 complex"
• Development of colour patterns in fishes.
• RNA-binding proteins, metabolism and a new role for the genome?
• Professor Marie Ohman - Editing of Non-coding RNA in the Brain of Mice and Men
• SRP gymnastics at the ribosome
• Genome transcription: from moleculesto systems
• How are Chromosomes Held Together
• The Origin of Specificity in Regulated Protein Degradation
• Activation and inhibition of the phosphoinositide 3-kinase family of enzymes
• Realising the full potential of single particle cryomicroscopy
• Monogenic Pain Disorders
• Leukocyte migration and gradient sensing in vivo: lessons from zebrafish
• Recursive splicing regulates use of poison exons within long neuronal genes
• Chromatin without Histones, Plastid Devolution, and Parasite Invasion Machinery: Diverse Eukaryotes Provide Unexpected Insights into Cell Evolution and Function
• Accurate Decision making during protein biogenesis
• Accurate Decision making during protein biogenesis
• "Structural characterisation of protein complexes by chemical cross-linking and mass spectrometry"
• Prof Paul Sternberg - LINKIN, a novel adhesion protein, is necessary for collective cell migration