Modelling active cell intercalations in Drosophila axis extension
- đ¤ Speaker: Alexander Fletcher (University of Sheffield)
- đ Date & Time: Friday 08 September 2023, 09:40 - 10:20
- đ Venue: Seminar Room 1, Newton Institute
Abstract
In this talk I will describe some of our modelling work to understand the dynamics and mechanics of active cell intercalations underlying germband extension in the Drosophila embryo, progressing from a vertex model featuring locally patterned cell-cell interaction forces to a more detailed ‘apposed cortex adhesion’ model. I will also discuss some of our work to implement a variety of ‘cell-based’ modelling approaches in a consistent computational framework.
Series This talk is part of the Isaac Newton Institute Seminar Series series.
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Alexander Fletcher (University of Sheffield)
Friday 08 September 2023, 09:40-10:20