University of Cambridge > Talks.cam > Genetics Seminar > Feedback control of the anaphase-telophase transition.

  Browse A-Z

Log in

University Account External (via Google)

🔐 Log In

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

ℹī¸ Information

Feedback control of the anaphase-telophase transition.

Download to your calendar using vCal

If you have a question about this talk, please contact Caroline Newnham .

Host: Viji Draviam

Faithful chromosome segregation during anaphase of mitosis requires the physical and synchronous separation of two sets of sister-chromatids that will give rise to genetically identical daughter cell nuclei. Critically, nuclear envelope reassembly at telophase must therefore enclosure each and entire set of sister-chromatids, implying spatiotemporal coordination with the mechanisms that govern anaphase. Using Drosophila melanogaster S2 cells has model system, we identified a novel feedback control mechanism that delays chromosome decondensation and nuclear envelope reformation is response to slow spindle elongation during anaphase. We show that this mechanism is dependent on a gradient of Aurora B activity at the spindle midzone. In this presentation I will present evidence in support of a new mitotic checkpoint that prevents premature chromosome decondensation and nuclear envelope reassembly before effective separation of sister chromatids is achieved.

This talk is part of the Genetics Seminar series.

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Heritage Research Group Annual Fair FW11, William Gates Building. Zoom link: https://cl-cam-ac-uk.zoom.us/j/4361570789?pwd=Nkl2T3ZLaTZwRm05bzRTOUUxY3Q4QT09&from=addon filmyzilla to watch free movies

Other talks

Sheref Mansy, topic TBA Dwarf Galaxies in the Local Universe Optimal metric and approximation of free boundary minimal surfaces Science & the Public in Action: Can and should climate scientists be activists? FILM: One With The Whale What Can a Spectrum Learn? AI Perspectives on the Kohn Laplacian of Sphere Quotients
 

Š 2006-2025 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity