Using metagenomics to identify emerging viral pathogens, and RNA silencing to combat them
- đ¤ Speaker: Luke Braidwood, Baulcombe Lab đ Website
- đ Date & Time: Friday 12 December 2014, 11:00 - 11:30
- đ Venue: Department of Plant Sciences, Large Lecture Theatre
Abstract
Maize lethal necrosis (MLN) is a synergistic viral maize disease. It has recently spread to South-East Asia and East Africa, where it represents a serious threat to a major food crop. The infection is produced by the interaction of Maize chlorotic mottle virus (MCMV) and maize-infecting Potyviridae viruses. Both MCMV and the Potyviridae can use a variety of insect vectors to spread between hosts. I am using next generation sequencing to survey the genomic diversity of viruses in East African maize. This sequence data will be used to identify conserved regions of the viral genomes which produce MLN , and artificial mircroRNAs will be designed to target these regions and inserted into maize. The ultimate aim is to produce maize varieties with increased resistance to MLN , thereby improving food security in East Africa. In addition I am using artificial innoculation and molecular methods to investigate the methods of pathogenesis and synergy between the viruses.
1st year graduate seminar
Series This talk is part of the Plant Sciences Departmental Seminars series.
Included in Lists
- All Talks (aka the CURE list)
- Biology
- Biology
- bld31
- CambPlants Hub
- Cambridge Centre for Data-Driven Discovery (C2D3)
- Cambridge Global Food Security
- Cambridge Global Food Security
- Cambridge Infectious Diseases
- Cambridge talks
- Chris Davis' list
- Department of Plant Sciences, Large Lecture Theatre
- Interested Talks
- Interesting talks- 1st try
- ji247's list
- Life Sciences
- Life Sciences
- ME Seminar
- my_list
- ndk22's list
- ob366-ai4er
- other talks
- Plant Sciences Departmental Seminars
- Reception - Plant Sciences
- rp587
- Trust & Technology Initiative - interesting events
- yk449
Note: Ex-directory lists are not shown.
![[Talks.cam]](/static/images/talkslogosmall.gif)

Luke Braidwood, Baulcombe Lab 
Friday 12 December 2014, 11:00-11:30