Decreasing the oxygenase activity of Rubisco: a synthetic biology approach
- đ¤ Speaker: Marek Szecowka (Hibberd Lab)
- đ Date & Time: Thursday 26 February 2015, 13:00 - 13:30
- đ Venue: Department of Plant Sciences, Large Lecture Theatre
Abstract
Substantial agricultural gains would be possible if the oxygenation of RuBisCO were bypassed. As yet, attempts at its manipulation have not resulted in improved C3 photosynthetic yield. As a part of consortium of laboratories in the UK and USA my research focuses on generating synthetic protein scaffolds enabling metabolic channeling in plants by tethering C4 pathway related enzymes in a cell and organelle specific manner. We plan to combine this approach together with expression of novel ion pumps designed in the collaborating laboratories, to deliver high concentration of CO2 around RuBisCO. This should enhance the efficiency of carbon fixation in the plant.
Components of the protein scaffold were successfully expressed and imported into chloroplasts where they form complexes. As ongoing work I am generating Arabidopsis thaliana lines expressing scaffold and scaffold interacting domains fused with C4 pathway related enzymes in a cell specific manner.
Series This talk is part of the Plant Sciences Departmental Seminars series.
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Marek Szecowka (Hibberd Lab)
Thursday 26 February 2015, 13:00-13:30