![[Search]](/static/images/search.gif){kind=small}
![[A-Z Index]](/static/images/az.gif){kind=small}
![[Contact]](/static/images/contact.gif){kind=small}
![[University of Cambridge]](/static/images/identifier2.gif){kind=small}
![[Talks.cam]](/static/images/talkslogosmall.gif)
Dr Déborah Bourc'his, Institut Curie, Paris 
Thursday 25 January 2018, 14:00-15:00
DNA methyltransferase(s), transposons and spermatogenesis
- 👤 Speaker: Dr Déborah Bourc'his, Institut Curie, Paris
- 📅 Date & Time: Thursday 25 January 2018, 14:00 - 15:00
- 📍 Venue: Biffen Lecture Theatre, Department of Genetics, Downing Site
Abstract
DNA methylation-based control of transposons is absolutely essential for the production of spermatozoa in mammals. In the mouse, this function is dependent upon the newly discovered DNMT3C DNA methyltransferase, which has specifically evolved by tandem duplication of the DNMT3B gene some 40 million years ago in the Muroidea lineagee. DNMT3C has the ability to selectively methylate the promoters of the most active transposons and only in the context of fetal spermatogenesis. As a key to understand the basis of such specialization, we will discuss our latest insights into the evolution of DNMT3C and the dynamics of de novo methylation of young transposons sequences during male germ cell development.
Series This talk is part of the Genetics Seminar series.
Included in Lists
- All Talks (aka the CURE list)
- Biffen Lecture Theatre, Department of Genetics, Downing Site
- Bioinformatics and other interests
- Biology
- Centre for Health Leadership and Enterprise
- CPB Maria
- DevBio
- Genetics Seminar
- Genetics Seminar Series
- Graduate-Seminars
- ji247's list
- Life Sciences
- Life Sciences
- ME Seminar
- my_list
- ndk22's list
- Neurons, Fake News, DNA and your iPhone: The Mathematics of Information
- other talks
- PMRFPS's
Note: Ex-directory lists are not shown.