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Structural Biology seminar list

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If you have a question about this list, please contact: Marko Hyvonen. If you have a question about a specific talk, click on that talk to find its organiser.

4 upcoming talks and 928 talks in the archive.

MRC LMB Seminar Series

LMB Seminar - Reconstructing biomolecular condensates for translation

UserRuth Lehmann, Whitehead Institute, MIT.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockFriday 27 March 2026, 11:00-12:00

MRC LMB Seminar Series

Francis Crick Lecture - From Cell Atlases to Medicines, with AI

UserAviv Regev, Head of Genentech R&ED.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 09 March 2026, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - New Perspectives on CDKs and Cell Cycle Control

UserSir Paul Nurse, The Crick Institute.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/97807820456?pwd=Zom7d6xnoBUHOEyOsTOQphtYGZTyGt.1.

ClockMonday 26 January 2026, 11:00-12:00

MRC LMB Seminar Series

Max Perutz Lecture - Transport through nuclear pores

UserDirk GΓΆrlich, Max Planck Institute for Multidisciplinary Sciences.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 19 January 2026, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - How the physical sciences can empower biology: Applications of single molecule fluorescence to the biosciences

UserDavid Klenerman, University of Cambridge.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/94171771196?pwd=LbKuOThopk72DktYw3WJWcjBOGlKgG.1.

ClockMonday 03 November 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - Quorum Sensing Across Domains: From Viruses to Bacteria to Eukaryotes

UserBonnie Bassler, Princeton University.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/99006584805?pwd=yFgF0P1zMvOJEKkOES4eNPpntaUodk.1.

ClockMonday 13 October 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - De-novo discovery of macrocyclic peptides and pseudo-natural products for therapeutic innovation

UserHiroaki Suga - The University of Tokyo.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/96488916942?pwd=BpCGRwD8hD8ec89yfaJ0yKPmV3o6lv.1.

ClockMonday 29 September 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - Ribosome Upside Down: Co-translational Protein Biogenesis at the Tunnel Exit - In person only

UserNenad Ban - ETH ZΓΌrich.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockWednesday 17 September 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - The structures and mechanisms that maintain ciliary proteostasis - In person only

UserAlan Brown, Harvard Medical School.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 15 September 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - Mechanisms of Translational Control: From Viral Hijacking to Codon-Dependent mRNA Surveillance - In person only

UserTakuhiro Ito, RIKEN Center for Integrative Medical Sciences.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 01 September 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - Modulation of TREM2 function and its role in anti-Amyloid immunotherapeutic approaches

UserChristian Haass - Ludwig Maximilian University of Munich.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/96372751903?pwd=C2hRQ8UF0B03vDp6IHGfWuTlsqzrTi.1.

ClockTuesday 22 July 2025, 11:00-12:00

MRC LMB Seminar Series

CANCELLED LMB Seminar - In vitro reconstitution of minimal cytoskeletal systems

UserMarileen Dogterom - TU Delft, Delft University of Technology.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/95584842300?pwd=V2DAKEE0bQXA4bbbSUryiRPELlhmzP.1.

ClockMonday 07 July 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - Cellular response to genetic change

UserAndy Fire - Stanford University School of Medicine.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 30 June 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - Fast and slow pathways of ribosomal subunit association

UserJoachim Frank, Columbia University.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockThursday 26 June 2025, 10:00-11:00

MRC LMB Seminar Series

LMB Seminar - Blueprints of Life: Understanding the Sex Chromosomes

UserJames Turner, The Francis Crick Institute.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/94132066038?pwd=OF2EjwrvRQxl0XgpGK0N5L4bDNaayi.1.

ClockMonday 19 May 2025, 11:00-12:00

MRC LMB Seminar Series

CΓ©sar Milstein Lecture: Mechanisms driving the rapid evolution of genomes

UserDavid Pellman - Dana-Faber Cancer Institute, Harvard University.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/97042445746?pwd=rjwSiStXxjdk1Q2tPOdRnqr8aM3qwn.1.

ClockThursday 24 April 2025, 10:00-11:00

MRC LMB Seminar Series

LMB Seminar - Transmission of Misfolded Proteins in Neurodegenerative Disorders: A Common Mechanism of Disease Progression

UserVirginia Man-Yee Lee, Center for Neurodegenerative Disease Research, University of Pennsylvania.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/99931963515?pwd=6FBGl1amJG2tfvl9ycgkErGpbebGw3.1.

ClockTuesday 08 April 2025, 11:30-12:30

MRC LMB Seminar Series

LMB Seminar - How small molecules rescue a folding disease: principles learned from the ion channel CFTR

UserJue Chen - Rockefeller University.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/93491001276?pwd=2utwaSIeA0haHVdOuRkZlBlQq6wzLb.1.

ClockMonday 07 April 2025, 15:00-16:00

MRC LMB Seminar Series

LMB Seminar - Higher Order Transient structures and the principle of dynamic connectivity in membrane signaling

UserRod MacKinnon - Rockefeller University.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/92311841585?pwd=auhAdp8eTD8Ca0xGZpaNlZrChEcHAr.1.

ClockMonday 07 April 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - One or two membranes? Investigating the transition between monoderm and diderm cell envelopes across the Tree of Bacteria - IN PERSON ONLY

UserSimonetta Gribaldo, Intstitut Pasteur.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 10 March 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - Cryo-OrbiSIMS – high resolution mass spectrometry imaging in the native biological state

UserIan Gilmore, National Physical Laboratory.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/92454273602?pwd=kKpRjV53ALrNtk3FXYDG1jqaNTjGa4.1.

ClockMonday 03 March 2025, 11:00-12:00

MRC LMB Seminar Series

The Francis Crick Lecture 2025 - The DNA Quadruplex Helix

UserShankar Balasubramaniam, University of Cambridge.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/93702571246?pwd=I6zsi0w8N5XcKg2gu0bac58rcyTfba.1.

ClockWednesday 19 February 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - Alpha-Synuclein and its aggregation: Past, Present and Future

UserMaria Grazia Spillantini, University of Cambridge, Dept of Clinical Neurosciences.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/98728840077?pwd=Z0MZ2xWLsyUC6fI31cIklaUbSYALwy.1.

ClockMonday 10 February 2025, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar - The immune system of bacteria - IN PERSON ONLY

UserRotem Sorek, Weizmann Institute of Science.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 27 January 2025, 11:00-12:00

MRC LMB Seminar Series

2024 Milstein Lecture: 11am Centrioles in homeostasis, disease and evolution: tiny organelles, multiple and critical functions - IN PERSON ONLY

UserMΓ³nica Bettencourt Dias.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 09 December 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Metabolism, Cellular Decisions and the Language That Unites Them

UserJared Rutter.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link:https://mrc-lmb-cam-ac-uk.zoom.us/j/97590440299?pwd=d3k2U3l1WENLbllGT1ZUODYyd3lFZz09.

ClockMonday 25 November 2024, 11:00-12:00

MRC LMB Seminar Series

2024 Max Perutz Lecture: Antisense Modulation of RNA Splicing for Rare Disease Therapy - In Person Only

UserAdrian R. Krainer, Ph.D., St. Giles Foundation Professor, Cold Spring Harbor Laboratory.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 11 November 2024, 11:00-12:00

MRC LMB Seminar Series

2024 John Kendrew Lecture: Wiring Specificity of Neural Circuits - In Person Only

UserLiqun Luo.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 04 November 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Molecular mechanisms that regulate the first cell fate decisions in human development - In Person Only

UserKathy Niakan.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 14 October 2024, 11:00-12:00

MRC LMB Seminar Series

CANCELLED - LMB Seminar: RNA Meets DNA: Dangerous Liaisons in the Genome

UserKarlene Cimprich - Stanford University School of Medicine, Department of Biochemistry.

HouseCANCELLED.

ClockThursday 03 October 2024, 10:30-11:30

MRC LMB Seminar Series

Francis Crick Lecture 2024: Neuronal circuits for body movements - In Person Only

UserSilvia Arber.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 30 September 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Feedback control of mitosis in the context of the kinetochore

UserAndrea Musacchio, Director, Department of Mechanistic Cell Biology, Max-Planck-Institute of Molecular Physiology.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/96608781341?pwd=MG5QMXVmOStXcFVtalBqUlBYc0tEdz09.

ClockMonday 23 September 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Linking nanoscale synapse organization, function and plasticity

UserDr Daniel Choquet - University of Bordeux Institute for Interdisciplinary Neuroscience and the Bordeaux Imaging Center.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link:https://mrc-lmb-cam-ac-uk.zoom.us/j/94686992877?pwd=Q0VlRmFsRXNta0ZJMVhlRnZqNEs3QT09.

ClockMonday 16 September 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Laser phase plate in cryo-EM and cryo-ET

UserHolger MΓΌller.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/99208619370?pwd=MkR4anNjVFhtbHlIQmRSZzBobWxNdz09.

ClockMonday 09 September 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Separate yet connected: mitochondrial and nuclear genome stability

UserAgnel Sfeir.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link:https://mrc-lmb-cam-ac-uk.zoom.us/j/91614790739?pwd=QncrTFFvNG1xWVZJOWhqL0lTcHVIQT09.

ClockMonday 01 July 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Mechanosensing in cancer invasion and metastasis

UserLaura M Machesky, Sir William Dunn Professor of Biochemistry, University of Cambridge.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/99537530757?pwd=UVk1YjIyeFY4QzNjNkhwa0xwbERoQT09.

ClockMonday 17 June 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Identification of alternative pathways for metabolism or cell death using haploid genetics

UserThijn Brummelkamp, Netherlands Cancer Institute/Oncode Institute.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link:https://mrc-lmb-cam-ac-uk.zoom.us/j/95178919042?pwd=OUp6RUN3a0dkNFZqWGxQV0p0T0JOZz09.

ClockMonday 03 June 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Evading ageing: Mitochondrial and proteostatic adaptations in oocytes

UserElvan Boke, Group Leader, Centre for Genomic Regulation (CRG), Barcelona, Spain .

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/92134536179?pwd=bHVnRkpmamhnWWY2bXpVMHAyblhlZz09.

ClockTuesday 07 May 2024, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar: Super-resolution imaging of transcription in living cells

UserIbrahim CissΓ©, Department of Biological Physics, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/99208619370?pwd=MkR4anNjVFhtbHlIQmRSZzBobWxNdz09.

ClockThursday 11 April 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Biosynthesis and degradation of the underappreciated green polymer cyanophycin

UserMartin Schmeing, Ph.D., James McGill Professor, Department of Biochemistry and Directeur, Centre de recherche en biologie structurale, McGill University.

HouseIn person in the LMB's Klug Seminar Room (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/96568201418?pwd=c3F0aCtOeTVwR3IyQzZYdkxoWHdPUT09.

ClockThursday 04 April 2024, 11:00-12:00

MRC LMB Seminar Series

CANCELLED: LMB Seminar: New therapeutic modalities based on pseudo-natural peptides, products, and neobiologics

UserProf. Hiroaki Suga, Ph.D, The University of Tokyo, Graduate School of Science, Department of Chemistry.

HouseN/A.

ClockMonday 26 February 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Cell volume and dry mass across time scales in cultured mammalian cells: from milliseconds in migrating and circulating cells to homeostasis during cycles of growth and division

UserMatthieu Piel, Institut Curie.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/96572384351?pwd=MkJzbE1qM2dGd0ZSTi9hTmV0elZ5dz09 .

ClockMonday 05 February 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: The allosteric landscape of a protein

UserBen Lehner FRS FMedSci, Head of Generative and Synthetic Genomics, Wellcome Sanger Institute, Cambridge, UK, ICREA Professor, Systems and Synthetic Biology, CRG, Barcelona, ES.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/96896374524?pwd=VFJYbkZmRlZQREJ6a1QwelRSdEZwdz09.

ClockMonday 29 January 2024, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: From regeneration to homeostasis: tissue-scale decision making

UserPros. Prisca Liberali.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/97161414783?pwd=UEhEZUdDSVVLbDU0Q2lPdFhPQ3M2UT09.

ClockMonday 15 January 2024, 11:00-12:00

MRC LMB Seminar Series

*CANCELLED* LMB Seminar: Alpha-Synuclein and its aggregation in neurodegenerative diseases

UserProf Maria Grazia Spillantini, Professor of Molecular Neurology, University of Cambridge.

HouseN/A.

ClockMonday 11 December 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Power to the protein: analyse, signal and protect with bacterial superglues

UserProfessor Mark Howarth, University of Cambridge.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/95625236862?pwd=NGttT1d6ay9SWFRqUHMvRWNPdDhyZz09.

ClockMonday 04 December 2023, 11:00-12:00

MRC LMB Seminar Series

Crick Lecture 2023: Innovating metagenomics to explore the strange world of archaeal extrachromosomal elements

UserJill Banfield, University of California, Berkeley.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/96751041497?pwd=SDgyU1NMdjFVdENscUZqams4Z1RWUT09 .

ClockMonday 27 November 2023, 11:00-12:00

MRC LMB Seminar Series

Perutz Lecture 2023: Decoding the protein dance

UserProf. Dr. Paola Picotti, Associate Professor for Molecular Systems Biology, Institute of Molecular Systems Biology, ETH Zurich.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockMonday 20 November 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Pharmacological Adaptation of Proteostasis to Ameliorate Aging-associated Degenerative Diseases

UserJeffery W. Kelly, The Scripps Research Institute.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/94698100541?pwd=L0RIZUcvY0dvYjhaRW5VU0pXNThKUT09.

ClockTuesday 07 November 2023, 11:00-12:00

MRC LMB Seminar Series

Kendrew Lecture 2023: Cryo-electron tomography or the power of seeing the whole picture

UserWolfgang Baumeister, Max Planck Institute of Biochemistry, Germany.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/98196424925?pwd=a0V2Z1FOYU5UZFgreHp1ckQ4Z2UyUT09.

ClockMonday 30 October 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Talking to cells: biomolecular ultrasound for imaging and control of cellular function in intact organisms

UserMikhail G. Shapiro, Max DelbrΓΌck Professor, Caltech.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/94069360553?pwd=djJlT09ZOTlENzNJVzRYVnp6WWVZQT09.

ClockTuesday 12 September 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Decoding the role of solute carriers in health and disease

UserProfessor Simon Newstead.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/94311710455?pwd=N05mNDk4ZXlDZWdUTzVnaHJTQzRWQT09.

ClockMonday 10 July 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Single-molecule studies reveal the dynamics of replication origin licensing

UserStephen P. Bell, MIT, Dept. of Biology and HHMI.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/93130142776?pwd=dEhGKzFGTkw2RGI1enhVSGg0Vm1VZz09.

ClockMonday 03 July 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: What do we know about (your) antibodies? Novel insights from novel techniques in mass spectrometry

UserAlbert Heck, University of Utrecht, The Netherlands.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/92910980652?pwd=U2V6MGFOOU9kbmRnckNaU05HaXl4QT09.

ClockMonday 19 June 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Blending Proteins: Democratising Access to Beautiful Molecular Landscapes

UserBrady Johnston.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/93844733292?pwd=RGczZ0szUnVxVUJOb0U5c1AvbWdhdz09.

ClockMonday 12 June 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Tissue genomics: High throughout tools for measuring and perturbing tissues

UserFei Chen.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/93095291087?pwd=NGRzTnRJb3M0YWxqOC8xQXVNUXBmQT09.

ClockMonday 15 May 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: The Extraordinary Life and Legacy of Sir John C. Kendrew

UserProfessor Paul Wassarman, Mount Sinai, New York.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/91598384955?pwd=RnE5M0p4bjU3bS8vMjFldHFadE9OZz09.

ClockTuesday 09 May 2023, 16:00-17:00

MRC LMB Seminar Series

Milstein Lecture 2023: Understanding the Hox timer by Using mammalian Pseudo-Embryos

UserDenis Duboule, Collège de France, Paris France, Federal Institute of Technology (EPFL), Lausanne, Switzerland.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) .

ClockThursday 26 January 2023, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar: Engineering a bacteria for lung therapy

UserProf. Luis Serrano.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/99349389275?pwd=ZHI3em1DQTA0VTlVLzkvUTN6ZGkxdz09.

ClockTuesday 17 January 2023, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Structural basis of how the BIRC6/SMAC complex regulates apoptosis and autophagy

UserTim Clausen, Research Institute of Molecular Pathology (IMP).

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/94050407947?pwd=ZFZZYkxhd0JsbGJuMFNHQnlzOSsydz09.

ClockThursday 08 December 2022, 10:00-11:00

MRC LMB Seminar Series

LMB Seminar: Mechanism and regulation P element transposition in Drosophila

UserDonald Rio, Professor of Biochemistry, Biophysics and Structural Biology, Dept. of Molecular and Cell Biology, University of California, Berkeley, USA.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/94108711681?pwd=cXN4VGlQVHBZYkpMUVJ0SXV3emtaUT09.

ClockTuesday 29 November 2022, 16:00-17:00

MRC LMB Seminar Series

New Frontiers in PKA Signaling

UserSusan Taylor, Professor of Chemistry and Biochemistry and a Professor of Pharmacology at the University of California, San Diego.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/99725572898?pwd=NG82MzVpQmczczAvdkZzN2lJNkt1UT09.

ClockWednesday 09 November 2022, 11:30-12:30

MRC LMB Seminar Series

Crick Lecture 2022: Neurobiology of Social and Sickness Behaviors

UserCatherine Dulac, Higgins Professor of Molecular and Cellular Biology, Lee and Ezpeleta Professor of Arts and Sciences, Howard Hughes Medical Institute Investigator, Department of Molecular and Cellular Biology, Harvard University.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/91021060396?pwd=c1o1TWVTSTNHTWM1dW5lcm54cURKQT09.

ClockThursday 03 November 2022, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Cryo-ET reveals sarcomere structures at molecular resolution

UserProf. Dr. Stefan Raunser, Director, Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/96648790745?pwd=Tkx6OVpoY01ieTRMTFMzZ0QvWWR2UT09.

ClockTuesday 18 October 2022, 11:00-12:00

MRC LMB Seminar Series

Regulation of mRNA translation and decay

UserDavid Bartel, Professor of Biology, MIT, HHMI, and Whitehead Institute.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/99553714360?pwd=bVRGN3o1a0dsazJIMnVIemlRbjltZz09.

ClockTuesday 27 September 2022, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Encoding tissue morphogenesis with genetics, mechanics and geometry

UserProfessor Thomas Lecuit, Group leader at IBDM and Turing Center for living systems, Marseille. Professor at Collège de France, Paris.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/91594582633?pwd=UlBaTk1uTHJ4bW9JbFMwSEZxRE0zdz09.

ClockThursday 08 September 2022, 11:00-12:00

MRC LMB Seminar Series

Milstein Lecture 2022 - Project Lightspeed – The discovery of the first Covid-19 mRNA Vaccine

UserΓ–zlem TΓΌreci, M.D., Professor Personalized Cancer Immunotherapy, Johannes Gutenberg University Mainz, Co-founder, CMO BioNTech, Germany.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/94050407947?pwd=ZFZZYkxhd0JsbGJuMFNHQnlzOSsydz09.

ClockTuesday 26 July 2022, 11:30-12:30

MRC LMB Seminar Series

Milstein Lecture 2022 - mRNA Cancer Vaccines

UserUgur Sahin, M.D., Professor Translational Oncology & Immunology, Johannes Gutenberg University Mainz, Co-founder, CEO BioNTech, Germany.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/94050407947?pwd=ZFZZYkxhd0JsbGJuMFNHQnlzOSsydz09.

ClockTuesday 26 July 2022, 10:00-11:00

MRC LMB Seminar Series

LMB Seminar - Using connectomes to accelerate studies of the neuronal control of behavior in Drosophila

UserGerald M. Rubin, Senior Group Leader, Janelia Research Campus, HHMI, LMB Fellow.

HouseIn person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/91661708050?pwd=WS9Ua0czQm9FaC9qaWk3S2VQMjE5dz09.

ClockThursday 26 May 2022, 11:00-12:00

MRC LMB Seminar Series

Aaron Klug Memorial Symposium

UserVarious - see Further Information.

HouseRegistration via https://www3.mrc-lmb.cam.ac.uk/sites/klug/.

ClockFriday 20 May 2022, 09:00-17:00

MRC LMB Seminar Series

Kendrew Lecture 2022: Chemogenetic and optogenetic technologies for probing molecular and cellular networks

UserAlice Ting - Professor of Genetics, of Biology and, by courtesy, of Chemistry, Stanford University, USA and Chan Zuckerberg Biohub Investigator .

HouseZoom link: https://mrc-lmb-cam-ac-uk.zoom.us/j/99780084619?pwd=V3RmYTdTbmlBLzFLd1NOR0hHcjFIZz09.

ClockThursday 12 May 2022, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar: Engineering Organoid Development

UserProfessor Matthias Lutolf, Roche Institute for Translational Bioengineering, Basel, Switzerland and Laboratory of Stem Cell Bioengineering, EPFL, Switzerland.

HouseZoom link: https://mrc-lmb-cam-ac-uk.zoom.us/j/97051627883?pwd=cUh3ZDZkT3I2bHdxVXo0TytZSEJkdz09.

ClockTuesday 19 April 2022, 11:00-12:00

MRC LMB Seminar Series

Max Perutz Lecture 2022: Therapeutic Opportunities in Glycoscience

UserCarolyn Bertozzi, Anne T. and Robert M. Bass Professor of Chemistry, Baker Family Director, Stanford ChEM-H, Howard Hughes Medical Institute Investigator, Stanford University.

HouseZoom: https://mrc-lmb-cam-ac-uk.zoom.us/j/92288963882?pwd=MEFqUURaRmJ1dkpTNkl1dzhDcHE2QT09.

ClockTuesday 29 March 2022, 16:00-17:00

MRC LMB Seminar Series

Milstein Lecture 2021: Organoids to model human diseases

UserHans Clevers, Professor in Molecular Genetics, Hubrecht Institute, Utrecht, The Netherlands.

HouseZoom: https://mrc-lmb-cam-ac-uk.zoom.us/j/96610458150?pwd=RmI5RUZZU0JRNzBBNlh3NnFWQWpjZz09.

ClockTuesday 30 November 2021, 11:00-12:00

MRC LMB Seminar Series

Crick Lecture 2021: Human Immune Responses to SARS-CoV-2 Infection or Vaccination

UserMichel C. Nussenzweig, Zanvil A. Cohn and Ralph M. Steinman Professor, The Rockefeller University, New York, USA.

HouseZoom: https://mrc-lmb-cam-ac-uk.zoom.us/j/98167346283?pwd=UStva0JBNFpiNTE4czlSS283WGJlQT09.

ClockMonday 15 November 2021, 11:00-12:00

MRC LMB Seminar Series

Interplay between tissue tension and tumor immunity

UserValerie Weaver, Director of the Center for Bioengineering and Tissue Regeneration and Professor in the Department of Surgery, UCSF, USA.

HouseZoom: https://mrc-lmb-cam-ac-uk.zoom.us/j/92866604568?pwd=TlljTHk5VGEzd2YzM3JHQkxOaWdRUT09.

ClockTuesday 02 November 2021, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar: Biomolecular condensates and their implications for physiology and disease

UserTony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.

HouseWebinar - https://zoom.us/j/92425532683?pwd=bXhPUkh0dm8xRlVmUkthREQwUnc4UT09.

ClockTuesday 19 October 2021, 11:00-12:00

MRC LMB Seminar Series

LMB Kendrew Lecture (part 2): Highly accurate protein structure prediction with AlphaFold

UserJohn Jumper, Research scientist and AlphaFold lead.

HouseYouTube link to watch the talk: https://youtu.be/6hlgADbBvZs.

ClockWednesday 13 October 2021, 16:00-17:00

MRC LMB Seminar Series

LMB Kendrew Lecture (part 1): Using AI to accelerate scientific discovery

UserDemis Hassabis, Founder & CEO DeepMind, AlphaFold project lead.

HouseYouTube link to watch the talk: https://youtu.be/6hlgADbBvZs.

ClockWednesday 13 October 2021, 14:30-15:30

MRC LMB Seminar Series

Using stem cell technology to combat age-related neurodegenerative diseases

UserSally Temple PhD, Scientific Director, Neural Stem Cell Institute, USA.

HouseWebinar - https://zoom.us/j/99447632193?pwd=QU9vbXliNXcvcXZqVFFBbHVpd2tSUT09.

ClockTuesday 27 July 2021, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar: The biomass distribution on Earth

UserRon Milo, Professor, Department of Plant and Environmental Sciences, Weizmann Institute of Science, Israel.

HouseWebinar - https://zoom.us/j/93763520674?pwd=WTlDZThITTFUaEpKL2xMZ1YzZWVkZz09.

ClockTuesday 06 July 2021, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Membrane Mechanics: cryo-EM insights and challenges

UserAdam Frost, Associate Professor, Biochemistry and Biophysics, UCSF, USA.

HouseWebinar - https://zoom.us/j/97224999053?pwd=aitsUFFSQ3dKVlM0MUFVWC83S0E0UT09.

ClockTuesday 29 June 2021, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar: Mechanisms of centriole assembly

UserPierre GΓΆnczy, Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland.

HouseWebinar - https://zoom.us/j/91953336333?pwd=ZnV2R1dNSW1FdVhmK1J6UmcvdnNOdz09.

ClockTuesday 22 June 2021, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Systemic regulation of brain aging and function

UserTony Wyss-Coray, D. H. Chen Professor II, Stanford University, USA.

HouseWebinar - Zoom link: https://zoom.us/j/91691820397?pwd=aUNFUFFib1V5S2V4RUswRmlhN0pRQT09.

ClockTuesday 25 May 2021, 16:00-17:00

MRC LMB Seminar Series

Perutz Lecture 2021: The coming of age of de novo protein design

UserProfessor David Baker, Director of the Institute for Protein Design, University of Washington, USA .

HouseWebinar - https://zoom.us/j/92141784758?pwd=MC9UVVBLaUdkTkg4dDdJb2RRaGhmUT09.

ClockTuesday 27 April 2021, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar: Molecular views into cellular functions by in-cell cryo-electron tomography

UserDr Julia Mahamid, Group Leader, EMBL Heidelberg, Germany.

HouseWebinar - https://zoom.us/j/97074945822?pwd=NWZvc3VEVWJxWmREVXJhaisxTkJ5dz09.

ClockTuesday 20 April 2021, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Functions of Ribosome-Associated Chaperones in Health and Disease

UserProf. Dr. Elke Deuerling, Chair of Molecular Microbiology, University of Konstanz, Germany.

HouseWebinar - https://zoom.us/j/97041423092?pwd=dDFuelNtb0o2cTdWL1BabFBhbldFQT09 .

ClockTuesday 16 March 2021, 11:00-12:00

MRC LMB Seminar Series

Rules of engagement: molecular arms races between host and viral genomes

UserDr. Harmit Singh Malik, Professor, Division of Basic Sciences & HHMI Investigator, Fred Hutchinson Cancer Research Center.

HouseWebinar - https://zoom.us/j/92208122335?pwd=UGJIN3k3TnJYNWloNFBhVDlOaldZUT09.

ClockTuesday 02 March 2021, 16:00-17:00

MRC LMB Seminar Series

Translation defects and neurological disease

UserSusan L Ackerman, PhD. Professor, Cellular and Molecular Biology Steven W. Kuffler Chair of Biology University of California San Diego USA/HHMI.

HouseWebinar - https://zoom.us/j/95280655660?pwd=RzhzSlQvWXFVS1dVdURPUUxocElkQT09 Passcode: 628922.

ClockTuesday 08 December 2020, 16:00-17:00

MRC LMB Seminar Series

Sir Martin Wood Prize Lecture: The emerging world of microbial rhodopsins in photobiology

UserKeiichi Inoue, Associate Professor, The Institute for Solid State Physics, The University of Tokyo.

House Webinar - register at https://nanoscience.oxinst.com/campaigns/sir-martin-wood-prize-lecture.

ClockThursday 26 November 2020, 11:00-12:00

MRC LMB Seminar Series

The African killifish: a vertebrate model to understand aging and β€˜suspended animation'

UserAnne Brunet, Michele and Timothy Barakett Professor of Genetics, Stanford University, USA.

House Webinar (via Zoom online).

ClockTuesday 03 November 2020, 16:00-17:00

MRC LMB Seminar Series

How is electrical signal generated?

UserNieng Yan, Shirley M. Tilghman Professor of Molecular Biology, Princeton University, USA.

HouseWebinar via Zoom.

ClockMonday 02 November 2020, 16:00-17:00

MRC LMB Seminar Series

RNP granules in health and disease (via Zoom)

UserRoy Parker, Investigator, Howard Hughes Medical Institute, Executive Director, BioFrontiers Institute, Distinguished Professor and Cech-Leinwand Endowed Chair of Biochemistry, University of Colorado Boulder, USA.

HouseWebinar via Zoom.

ClockTuesday 22 September 2020, 16:00-17:00

MRC LMB Seminar Series

Study virus assembly and host interactions in vitro and in cells by cryoEM and cryoET

UserPeijun Zhang, Professor of Structural Biology and Wellcome Trust Investigator, University of Oxford .

HouseWebinar via Zoom - https://zoom.us/j/97493748184?pwd=Z1dZM2pxUk16QytPeU5NVWZ3bnZmdz09 Meeting ID: 974 9374 8184 Passcode: 404662.

ClockTuesday 08 September 2020, 11:00-12:00

MRC LMB Seminar Series

Perutz LMB Seminar Series: How our chromosomes are replicated

UserJohn Diffley, Associate Research Director, the Francis Crick Institute, London, UK.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 26 February 2020, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar: Mitochondrial Behaviour

UserJodi Nunnari, Distinguished Professor, Department of Molecular and Cellular Biology, Univeristy of California, Davis.

HouseMax Perutz Lecture Theatre, MRC Laboratory of Molecular Biology.

ClockTuesday 25 February 2020, 16:00-17:00

MRC LMB Seminar Series

Milstein LMB Seminar Series: Stem Cells in Silence, Action and Cancer

UserElaine Fuchs, Rebecca C. Lancefield Professor Investigator, Howard Hughes Medical Institute .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 27 January 2020, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series: Host factors that shape influenza evolution.

UserWendy Barclay.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 06 December 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series: Folding and assembly of newly synthesized proteins revealed by ribosome profiling

UserBernd Bukau, Center for Molecular Biology of Heidelberg University and German Cancer Research Center.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 21 November 2019, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series - Kendrew Lecture - How a ubiquitin-like protein brings ubiquitylation to life

UserBrenda Schulman, Director at the Max Planck Institute of Biochemistry.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 03 October 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Organelle contact sites: a new layer in the organization of Eukaryotic cells

UserBenoit Kornmann, Associate professor – Dept. of Biochemistry, Oxford University, and C.W. Maplethorpe Tutorial Fellow in Bio-chemistry – St-Hugh’s College, Oxford University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 12 September 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Antibodies against Ebola and Lassa: A Global Collaboration

UserErica Ollmann Saphire, Professor Department of Immunology and Microbiology California Campus.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 23 July 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - Francis Crick Lecture - Innovation by Evolution: Bringing New Chemistry to Life

UserFrances Arnold, California Institute of Technology, Pasadena, U.S.A..

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 18 July 2019, 16:00-17:00

MRC LMB Seminar Series

What next for your career in science?

UserRebecca Aarons, Jenny Gallop, Emma Gleave.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 28 June 2019, 12:00-13:00

MRC LMB Seminar Series

LMB Seminar Series - Structural and mechanistic studies of key components in DNA damage signalling and repair

UserXiaodong Zhang.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 18 June 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series: Folding and assembly of newly synthesized proteins revealed by ribosome profiling

UserBernd Bukau, Center for Molecular Biology of Heidelberg University and German Cancer Research Center.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 14 June 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Towards a mechanistic understanding of cellular processes by cryo-EM

UserGaia Pigino, Research Group Leader at the MPI-CBG.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 28 May 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - The 100,000 genomes project and beyond

UserTim Hubbard, Professor of Bioinformatics & Head of Department, King’s College London.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 23 May 2019, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

UserNieng Yan, Professor of Molecular Biology, Princeton University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockSaturday 18 May 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series - Modifications of RNA: their function and role in cancer

UserTony Kouzarides, PhD FRS FMedSci, Professor of Cancer Biology, Cancer Research UK Gibb Fellow, Director of the Milner Therapeutics Institute, Member of the Department of Pathology.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 16 May 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Synthesis and hydrolysis of the gram-positive cell wall: revisiting old models with new data

UserDavid Rudner, Dept. of Microbiology and Immunobiology, Harvard Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 03 May 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - CryoEM of proton pumping macromolecular machines

UserJohn Rubinstein.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 29 April 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - Factors and Functions of ER Membrane Contact Sites

UserGia Voeltz PhD, HHMI Investigator and Professor University of Colorado at Boulder.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 10 April 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - Pathogen restriction and host specificity: insights from the human pathogen Salmonella Typhi

UserJorge Galan, PhD, DVM, Lucille P. Markey Professor of Microbial Pathogenesis and Professor of Cell Biology; Chair, Department of Microbial Pathogenesis.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 05 April 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

UserGerry Rubin, Vice President, HHMI, and Executive Director, Janelia Research Campus.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 03 April 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

UserGerry Rubin, Vice President, HHMI, and Executive Director, Janelia Research Campus.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 03 April 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

UserJulie Ahringer, PhD FMedSci, Director, Wellcome Senior Research Fellow, Professor of Genetics and Genomics, Member of the Department of Genetics.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 27 March 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

UserJulie Ahringer, PhD FMedSci, Director, Wellcome Senior Research Fellow, Professor of Genetics and Genomics, Member of the Department of Genetics.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 27 March 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series - ANNA KARENINA AND THE GENETICS OF COMPLEX DISEASE: DE NOVO MUTATIONS IN SCHIZOPHRENIA

UserMary-Claire King, human geneticist professor, University of Washington.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 14 March 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Animating Molecular Biology

UserJanet Iwasa, Assistant Professor, Biochemistry Department, University of Utah.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 08 March 2019, 11:30-12:30

MRC LMB Seminar Series

LMB Seminar Series Milstein Lecture - Intracellular Membrane Contact Sites, Lipid Dynamics and Neurodegeneration

UserPietro De Camilli Departments of Neuroscience and Cell Biology, Howard Hughes Medical Institute, Kavli Institute for Neuroscince, Yale University School of Medicine.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 05 March 2019, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series - Stem cells, regeneration and organoid cultures

UserMeritxell Huch, Wellcome Sir Henry Dale Fellow, Member of the Department of Physiology, Development and Neuroscience.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 28 February 2019, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

tRNA Modifications and Decoding Errors

UserProfessor Eric Westhof (Institut de Biologie MolΓ©culaire et Cellulaire du CNRS, UniversitΓ© de Strasbourg).

HouseJean Thomas Lecture Theatre, Sanger Biochemistry Building.

ClockWednesday 20 February 2019, 16:00-18:00

MRC LMB Seminar Series

LMB Seminar Series-Epigenetic inheritance in mammals

UserAnne Ferguson Smith, Department of Genetics, Wellcome Trust Senior Investigator.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 30 January 2019, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

A Saposin-lipoprotein nanoparticle system for membrane proteins

UserDr Jens Frauenfeld (CEO Salipro Biotech, Sweden).

HouseJean Thomas Lecture Theatre, Sanger Biochemistry Building.

ClockMonday 03 December 2018, 15:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-Solving a 3D jigsaw with 1000 pieces - Structure and assembly of the nuclear pore complex

UserMartin Beck.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 03 December 2018, 11:00-12:00

MRC LMB Seminar Series

Perutz Lecture- How synapses work: Architecture and mechanism of neurotransmitter receptors and transporters

UserEric Gouaux.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 29 November 2018, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Capturing the 3D Folds of Whole Mammalian Genomes in Single Cells

UserDr Tim Stevens (Cell Biology Division, LMB).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 28 November 2018, 10:15-11:15

MRC LMB Seminar Series

LMB Seminar Series-Title to follow

UserCarrie Partch.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 20 November 2018, 11:00-12:00

MRC LMB Seminar Series

Reconstructing Tissue Architecture by Single Cell Genomics

UserSarah Teichmann.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 15 November 2018, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series-Mycobacterium tuberculosis infection of host cells in time and space

UserMax Gutierrez.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 01 November 2018, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Protein:protein recognition in the Ubiquitin Proteasome-degradation System (UPS) and Membrane Surface Complexes from the Ras-family

UserDr Andrew Byrd (Head of Macromolecular NMR, National Cancer Institute, Maryland).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 31 October 2018, 16:00-18:00

MRC LMB Seminar Series

Light Sleep

UserGero Miesenboeck.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 24 October 2018, 11:00-12:00

MRC LMB Seminar Series

Evidence that sub-cellular oscillators may time and execute organelle biogenesis

UserJordan Raff.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 20 September 2018, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series - Kinetochore Structure

UserSteve Harrison.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 28 June 2018, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structural studies of a DNA unwinding machine

UserDr Laura Spagnolo (University of Glasgow).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 20 June 2018, 10:15-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Architecture of PIKK Kinases and their molecular mechanisms of regulation

UserDr Taiana De Oliveira (Astra Zeneca).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 20 June 2018, 10:15-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Protein and Peptide Mass Spectrometry Analysis

UserDr Anja Andrejeva (Cambridge Centre for Proteomics).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 06 June 2018, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series-Title to follow

UserMichael Hall.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 29 May 2018, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-Title to follow

UserTitia De Lange Rockefeller.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 23 May 2018, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Solution-based angular measurements of protein structure and conformational change by second-harmonic generation (SHG)

UserDr Joshua Salafsky (Founder and CSO, Biodesy Inc, San Francisco).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 23 May 2018, 10:30-11:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Fragment based inhibition of CK2Ξ±

UserDr Paul Brear (Hyvonen Group).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 16 May 2018, 10:30-11:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Correlative tweezers fluorescence microscopy: one step towards real-time single-molecule biology

UserDr Joanna Andrecka (Lumicks).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 09 May 2018, 10:30-11:30

MRC LMB Seminar Series

Kendrew Lecture-Electron cryo-microscopy

UserJacques Dubochet.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 26 April 2018, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Substrate reduction enabled by structural biology as therapy for metabolic disorders

UserDr Gustavo Arruda Bezerra (Structural Genomics Consortium – University of Oxford).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 25 April 2018, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Toward the Reconstitution of the Maturation of Okazaki Fragments Multiprotein Complex in Human at the Single Molecule Level

UserDr Luay Joudeh (Pellegrini Group).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 28 March 2018, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Using Computational Structure Biology to Study Diseases that cause Major Health Concerns in Brazil

UserDr Pedro Torres.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 21 March 2018, 10:30-11:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Not Too Big - Not Too Small: Fragment Antibody Drug Candidates as Alternatives to Antibodies for Solid Tumours

UserDr Gokhan Yahioglu (Director of Medicinal Chemistry, Antikor Biopharma Ltd).

HouseBiochemistry Seminar Room, Sanger Building.

ClockMonday 19 March 2018, 10:15-11:15

MRC LMB Seminar Series

LMB Seminar Series-Title to follow

UserLukas Kapitein.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 15 March 2018, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Mycobacterium Tuberculosis Physiology: The Intricate Interplay between Drug Tolerance and Drug Resistance

UserCaroline Pule (Faculty of Medicine, Stellenbosch University, South Africa).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 07 March 2018, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Shortening Tuberculosis Chemotherapies: Elucidating the Molecular genetic programs of persistence of M. tuberculosis

UserProfessor W. Jacobs, Howard Hughes Medical Institute, NY.

HouseBiochemistry Seminar Room, Sanger Building.

ClockMonday 26 February 2018, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Human 2-oxoacid-dependent Oxygenases

UserDr M. S. Islam (Department of Biochemistry, University of Cambridge).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 24 January 2018, 10:30-11:15

MRC LMB Seminar Series

Kendrew Lecture- Illuminating biology at the nanoscale and systems scale by imaging

UserXiaowei Zhuang .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 15 January 2018, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The simple reason that M. avium subspecies paratuberculosis has been missed as a major human pathogen is that, unknowingly, it's been treated since 1942

UserDr Robert Greenstein (VA Medical Center, Bronx, NY).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 13 December 2017, 10:15-11:15

MRC LMB Seminar Series

Localised RNA-based mechanisms underlie neuronal wiring

UserChristine Holt.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 04 December 2017, 11:00-12:00

MRC LMB Seminar Series

Exploring and Exploiting the Diversity of Secretory Routes in Mammalian Cells

UserFranck Perez.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 28 November 2017, 14:00-15:00

MRC LMB Seminar Series

Genomic and cellular integration of bacterial endosymbionts into host cells

UserJohn McCutcheon.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 03 November 2017, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Signalling through interleukin/interferon receptors: outside and inside of the cell

UserDr. Alexander Wlodawer (Chief, Macromolecular Crystallography Laboratory, NCI-Frederick).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 11 October 2017, 10:15-11:15

MRC LMB Seminar Series

LMB Seminar Series- Stories from the first year of the Central Oxford Structural Microscopy and Imaging Centre - closing in on bacterial protein secretion systems.

UserSusan Lea.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 02 October 2017, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series- How T cells control secretion to optimise target cell killing

UserGillian Griffiths.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 19 September 2017, 11:00-12:00

MRC LMB Seminar Series

Crick Lecture-The Surprising Chemistry of Non-enzymatic RNA Replication

UserJack Szostack, Harvard, USA .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 07 September 2017, 16:00-17:00

MRC LMB Seminar Series

Integrated structural biology of gene transcription

UserPatrick Cramer, Max Planck Institute.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 05 September 2017, 16:00-12:00

MRC LMB Seminar Series

LMB Seminar Series-RNA quality control and the nuclear RNA exosome

UserChris Lima.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 14 July 2017, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series- Title to follow

UserAndreas Matouschek, Northwestern University, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 03 July 2017, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-DNA Methylation: From stem cell differentiation to chromatin organisation

UserMargaret Goodell.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 20 June 2017, 11:15-12:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Linking Structural Biology and Clinical Genomics: Purine Nucleotidase in Relapsed Leukemia

UserDr. AleΕ‘ HnΓ­zda (Academy of Sciences of the Czech Republic, Prague; From 1st June: Department of Biochemistry, University of Cambridge).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 31 May 2017, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Revolutionary Cryo-EM: the Potential Power to Visualize High Resolution Dynamic Structures

UserDr Kai Zhang (LMB).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 24 May 2017, 10:15-11:15

MRC LMB Seminar Series

Charting the response to DNA damage

UserDan Durocher, University of Toronto, Faculty of Medicine.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 15 May 2017, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Rebuilding the HDX-MS Method to Support Integrative Methods in Structural Biology

UserDr David Schriemer (University of Calgary, Alberta).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 10 May 2017, 10:15-11:15

MRC LMB Seminar Series

Mulitispectral imaging to uncover the organelle interactome

UserJennifer Lippincott-Schwartz, National Institute of Health, Maryland, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 08 May 2017, 16:00-17:00

MRC LMB Seminar Series

Max Perutz Lecture- Antisense transcription and epigenetic switching

UserCaroline Dean, John Innes Centre, Norwich.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 27 April 2017, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

High-Throughput Fragment-Based Drug Discovery at Diamond Synchrotron: Robots can do much of the work to screen in FBDD!

UserProf Frank von Delft (Diamond Light Source / Structural Genomics Consortium - Oxford).

HouseBiochemistry Seminar Room, Sanger Building.

ClockMonday 03 April 2017, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

COSMIC Catalogue of Cancer Mutations and the 3D Proteome

UserSimon Forbes & Harry Jubb (Sanger Institute, Wellcome Genome Campus).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 29 March 2017, 10:15-11:15

MRC LMB Seminar Series

RNA methylation in development and disease

UserMichaela Frye, Stem Cell Institute and Department of Genetics, Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 24 March 2017, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Dynamic interactions and fuzzy structures in protein complexes and higher-order assemblies

UserDr Monika Fuxreiter.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockThursday 23 March 2017, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Using Integrative Methods in Structural Biology to Understand Protein Structure

UserDr Daniel Saltzberg (University of California, San Francisco).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 08 March 2017, 10:15-11:15

MRC LMB Seminar Series

Membrane proteins - the lipid connection

UserCarol Robinson, university of Oxford.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 07 March 2017, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Computational study of mutations in proteins

UserProfessor Douglas Pires (Centro de Pesquisas RenΓ© Rachou, FIOCRUZ - Minas Gerais, Brazil).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 01 March 2017, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Myc and MexR: conformational selection and fuzzy complexes in transcriptional regulation

UserProf Maria Sunnerhagen (Linkoping University, Sweden).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 28 February 2017, 14:30-15:30

MRC LMB Seminar Series

Milstein Lecture- Molecular Mechanisms of Synaptic Transmission

UserThomas SΓΌdhof, Department of Molecular and Cellular Physiology, Stanford.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 09 February 2017, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

What's new at PDBe?

UserDr Deepti Gupta and Dr John Berrisford (PDBe).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 25 January 2017, 10:15-11:15

MRC LMB Seminar Series

Comparative studies of intrinsically disordered proteins

UserProfessor Jane Clarke, Department of Chemistry, University of Cambridge .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 23 January 2017, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Phosphoproteomic strategies reveal global impact of kinase inhibitors on regulatory kinase networks and the phosphoproteome

UserProf David Litchfield (University of Western Ontario).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 16 November 2016, 14:30-16:00

MRC LMB Seminar Series

Molecular Chaperone Functions in Protein Folding and Quality Control

UserUlrich Hartl, max Planck Institute of Biochemistry.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 15 November 2016, 12:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

A computational framework for optimizing combination drug therapies

UserDr Michael Lyons (Colorado State University).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 26 October 2016, 10:15-11:15

MRC LMB Seminar Series

Kendrew Lecture- Bacterial Quorum Sensing and its Control

UserBonnie Bassler, Princeton University, USA .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 24 October 2016, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structure and Function of TIFA - A New Player in Immunity and Cancer

UserProf Ming-Daw Tsai (Academia Sinica in Taiwan).

HouseBiochemistry Seminar Room, Sanger Building.

ClockMonday 10 October 2016, 15:00-16:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Interactive molecular dynamics for improved model building and exploration in structural biology

UserDr Tristan Croll (CIMR, Cambridge).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 28 September 2016, 10:15-11:15

MRC LMB Seminar Series

TBC

UserAmita Sehgal.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 27 September 2016, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Predicting the impact of natural and disease variants on protein function

UserProfessor Rob Russell (Heidelberg University).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 13 July 2016, 10:15-11:15

MRC LMB Seminar Series

TBC

UserLaurence Pearl, Sussex.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 12 July 2016, 11:00-12:00

MRC LMB Seminar Series

TBC

UserRichard Youle.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 01 July 2016, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Targeting Trehalose and Methylglucose Lipopolysaccharide Pathways of M. tuberculosis

UserNupur Verma (Department of Biochemistry, Cambridge).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 15 June 2016, 10:15-11:15

MRC LMB Seminar Series

Pathological vs Reversible Amyloid

UserDavid Eisenberg, University of California.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 10 June 2016, 11:00-12:00

MRC LMB Seminar Series

Pathological vs Reversible Amyloid

UserProf. David Eisenberg, Dept. Chemistry and Biochemistry, University of California.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 10 June 2016, 11:00-12:00

MRC LMB Seminar Series

Perutz Lecture 2016

UserRon Vale, University of California.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 02 June 2016, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

TBC

UserDr Owen Davies (Newcastle University).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 01 June 2016, 10:15-11:15

MRC LMB Seminar Series

Kendrew lecture- Post-translational regulation of cell signalling

UserTony Hunter.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 25 May 2016, 15:00-16:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Matching density maps of macromolecular assemblies from Cryo-EM and assessment of fitted atomic models

UserDr Agnel Praveen Joseph.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 25 May 2016, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The 3D structures of genomes in single cells reveal principles of nuclear organization

UserDr Tim Stevens (LMB, Cambridge).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 18 May 2016, 10:15-11:15

MRC LMB Seminar Series

Mapping cancer origins

UserProffessor Richard Gilbertson, Cancer Research UK, Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 03 May 2016, 12:00-13:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The E. coli replisome caught in the act by cryo-EM and single molecule microscopy

UserDr Meindert Lamers (LMB).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 27 April 2016, 14:00-15:00

MRC LMB Seminar Series

Learning and motivation toggle feed-forward inhibition in the Drosophila mushroom body

UserScott Waddell.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 27 April 2016, 11:00-12:00

MRC LMB Seminar Series

CRISPR-Cas: origin of adaptive immunity from selfish genetic elements and the evolutionary continuum from Darwin to Lamarck

UserEugene Koonin.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 18 March 2016, 11:00-12:00

MRC LMB Seminar Series

Structure of TRP channel by single particle cryo-EM

UserYifan Cheng.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 16 March 2016, 11:00-12:00

MRC LMB Seminar Series

Cell wall deficient (L-form) bacteria: from cell biology to the origins of life

UserJeff Errington.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 03 March 2016, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Pregnancy outcome prediction using placenta epigenetic data

UserDr Sung Gong (Clinical School of Medicine).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 02 March 2016, 10:15-11:15

MRC LMB Seminar Series

mRNA stability is substantially dictated by the action of the ribosome

UserRachel Green, Johns Hopkins University, School of Medicine.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 25 February 2016, 10:30-11:30

MRC LMB Seminar Series

Crick 2016 Lecture-DNA Sequence and the Epigenome Entwined

UserAdrian Bird.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 16 February 2016, 11:30-12:30

MRC LMB Seminar Series

A chemical approach to understanding cell division

UserUlrike Eggert.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 02 February 2016, 16:15-17:15

MRC LMB Seminar Series

Protein folding homeostasis in the endoplasmic reticulum: tuning a chaperone

UserDavid Ron, University of Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 29 January 2016, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Protein transport to the endoplasmic reticulum

UserDr Rebecca Voorhees (LMB).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 20 January 2016, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Computational approaches to investigate protein-nucleic acid and protein-protein interactions

UserDr Sony Malhotra (Department of Biochemistry).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 16 December 2015, 10:15-11:15

MRC LMB Seminar Series

Milstein Lecture-Phosphoinositide 3-Kinase and Cancer Metabolism

UserLewis Cantley, Meyer Cancer Center, Weill Cornell Medicine and New York Presbyterian Hospital, New York.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 14 December 2015, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Mapping of ligand binding site and activation mechanism of APJ receptor

UserPrashant Kumar (Department of Biochemistry).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 02 December 2015, 10:15-11:15

MRC LMB Seminar Series

In the beginning it was dark: Hydrothermal vents and the origin of life (real microbes)

UserWilliam Martin, UniversitΓ€t DΓΌsseldorf.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 26 November 2015, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Dr Paul Brear - Inhibiting CK2Ξ± from outside the active site

UserPaul Brear - Department of Biochemistry.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 25 November 2015, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Prof Song Tan - TBC

UserProfessor Song Tan (Penn State University).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 18 November 2015, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Fitting atomic structures into EM density maps

UserDr Arun Prasad Pandurangan (Department of Biochemistry).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 04 November 2015, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Migle Kisonaite - "Structure of Gremlin-1: Insights into the Mechanism of Bone Morphogenetic Protein Antagonism" and Xuelu Wang "Understanding of the Pro-domain in TGF-Ξ² Superfamily: Structure and Characterisation of Pro-activin A"

UserXuelu Wang and Migle Kisonaite - Department of Biochemistry.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 28 October 2015, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

ARCIMBOLDO, an ab initio approach to MR phasing

UserIsabel Uson (Molecular Biology Institute of Barcelona).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 21 October 2015, 10:15-11:15

MRC LMB Seminar Series

Crick Lecture- The transformative CRISPR-Cas9 genome engineering technology: lessons learned from bacteria

UserEmmanuelle Charpentier .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 02 October 2015, 15:15-16:15

MRC LMB Seminar Series

Plasticity of Cancer Cells : Lessons from Glioblastoma

UserInder Verma, Salk Institute for Biological Studies.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 04 September 2015, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Atomic resolution cryoEM structure of bacteriophage

UserProf. Wah Chiu, Baylor College of Medicine, Texas.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 02 September 2015, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Modulating Protein-Protein Interactions

UserDr Jessica Holien - St. Vincent's Institute for Medical Research.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 26 August 2015, 15:00-16:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Title to be confirmed

UserDr Dijana Matak-Vinkovic, Dept. Chemistry, Cambridge.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 24 June 2015, 10:15-11:15

Centre for Molecular Science Informatics

Crystallography & Compchem Hack Weekend 20/21 June

UserSpeaker to be confirmed.

HouseCentre for Molecular Informatics, Dept. of Chemistry.

ClockSaturday 20 June 2015, 09:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structural Biology and Transmembrane Signalling: Understanding a 'Double-edged' Receptor, DCC

UserJia-Huai Wang (Harvard).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 17 June 2015, 10:15-11:15

MRC LMB Seminar Series

Persister Cells and the Search for Sterilizing Antibiotics

UserKim Lewis.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 15 June 2015, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Impact of rapid whole-genome sequencing on diagnostic and public health microbiology

UserDr Claudio U. KΓΆser, Dept. Medicine and Wellcome Trust Genome Campus.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 03 June 2015, 10:15-11:15

MRC LMB Seminar Series

Structural Mechanisms in the Tyrosine Kinases that Initiate Immunological Signaling

UserProfessor John Kuriyan, University of California.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 21 May 2015, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structural Mechanisms in Protein Kinase Regulation

UserProfessor John Kuriyan, Berkeley.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 20 May 2015, 10:15-11:15

MRC LMB Seminar Series

Regulation of proteasome function in normal and disease states

UserProfessor Alfred Goldberg, Harvard Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 15 May 2015, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Predicting drug-target binding kinetics through enhanced sampling simulations

UserProfessor Francesco Gervasio, Dept. Chemistry, University College London.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 13 May 2015, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Biodiversity and Drug Discovery

UserProfessor Glaucius Oliva, Universidade de SΓ£o Paulo.

HouseBiochemistry Seminar Room, Sanger Building.

ClockThursday 07 May 2015, 16:30-17:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Recent advances in high resolution cryo-EM structure determination

UserXiaochen Bai, LMB-MRC.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 29 April 2015, 10:15-11:30

MRC LMB Seminar Series

Chromatin unloading of the replicative DNA helicase during replication and repair

UserJohannes Walter.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 08 April 2015, 16:15-17:15

MRC LMB Seminar Series

Insights from a model of breast tumor heterogeneity

UserGreg Hannon, CRUK, Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 26 March 2015, 16:15-17:15

MRC LMB Seminar Series

Remodeling of the erythroid proteome

UserDan Finley, Harvard.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 17 March 2015, 16:15-18:00

MRC LMB Seminar Series

Synthetic Probes for live-cell imaging

UserKai Johnsson.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 11 March 2015, 16:15-18:00

MRC LMB Seminar Series

Tbc

UserJeff Errington.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 03 March 2015, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Dr Meindert Lamers - Title to be confirmed

UserDr Meindert Lamers - LMB.

HouseBiochemistry Seminar Room, Sanger Building, Tennis Court Road.

ClockWednesday 25 February 2015, 10:15-11:15

MRC LMB Seminar Series

Prion propagation and neurotoxicity

UserProf. John Collinge, UCL .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 19 February 2015, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Dr Isaac Westwood - Title to be Confirmed

UserDr Isaac Westwood - Institute of Cancer Research.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 18 February 2015, 10:15-11:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Dr Christian Ottmann, Title to be confirmed

UserDr. Christian Ottmann Associate Professor, (UHD) Molecular Cell and Structural Biology, Chemical Biology, Dpt. of Biomedical Engineering and Institute for Complex Molecular Systems, Technische Universiteit, EINDHOVEN.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 04 February 2015, 10:15-11:15

MRC LMB Seminar Series

Taming a protein destruction machine

UserNicolas Thoma, Friedrich Miescher Institute for Biomedical Reearch, Basel, Switzerland.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 29 January 2015, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Investigating the human proteasome by cryo-EM - an emerging tool for structural based drug design

UserDr Paula de Fonseca - MRC LMB.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 28 January 2015, 10:15-11:30

MRC LMB Seminar Series

Title to be confirmed

UserDavid Ron, Cambridge University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 27 January 2015, 16:15-17:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Dr Takashi Ochi and Dr Qian Wu

UserDr Takashi Ochi, Department of Biochemistry, University of Cambridge, u. k.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 21 January 2015, 10:15-11:30

MRC LMB Seminar Series

Local and Global Regulation of Meiotic Prophase by Post-Translational Protein Modification

UserNeil Hunter.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 15 December 2014, 16:15-18:00

MRC LMB Seminar Series

Max Perutz Lecture 2014: C. elegans surveillance of conserved cellular components to detect and defend pathogen attacks, real or imagined

UserGary Ruvkun, MGH Harvard.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 05 December 2014, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Tools for refinement against low resolution X-ray data and fit to EM reconstructions

UserDr Garib Murshudov, LMB, MRC.

HouseBiochemistry Lecture Theatre, Sanger Building, Tennis Court Road.

ClockWednesday 03 December 2014, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Identification and characterization of interaction sites with MD simulations of mixed solvents – Application to non-standard targets

UserProfessor Xavier Barril, ICREA Research Professor at Barcelona University, Spain.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 12 November 2014, 10:15-11:15

MRC LMB Seminar Series

The amazing hepatocyte: master of disguise and adaptation

UserDr Markus Grompe.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 10 November 2014, 16:15-18:00

MRC LMB Seminar Series

Genome stability and instability during repair of a broken chromosome

UserJim Haber, Director, Rosenstiel Basic Medical Sciences Research Center.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 06 November 2014, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

(1) An introduction to Gene Synthesis - capabilities and uses. (2) An introduction to precise genome editing with TAL effectors and CRISPR

UserNikolai Netuschil and Nahush Karnataki. ThermoFisher Scientific.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 29 October 2014, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Support Science and Diamond Light Source

UserCarina Lobley, DLS.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 15 October 2014, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Professor Randy Read - title to be comfirmed

UserProfessor Randy Read, CIMR, Cambridge.

HouseSeminar Room 2, Hopkins Building.

ClockWednesday 08 October 2014, 10:15-11:15

MRC LMB Seminar Series

Crick Lecture 2014: How Aneuploidy Drives Cancer

UserStephen Elledge, Gregor Mendel Professor of Genetics, Department of Genetics, Harvard Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 19 September 2014, 16:15-18:00

MRC LMB Seminar Series

Feedback control of cell division

UserAndrea Musacchio, Director, Department of Mechanistic Cell Biology, Max-Planck Institute of Molecular Physiology .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 18 September 2014, 16:15-18:00

MRC LMB Seminar Series

From static structures to molecular movies: pushing the boundaries of X-ray Crystallography

UserWei Yang, NIH, Bethesda, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 05 September 2014, 16:15-18:00

MRC LMB Seminar Series

The Consequences of Whole Genome Duplications

UserProf David Pellman, Professor of Cell Biology, Harvard Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 22 July 2014, 16:15-18:00

MRC LMB Seminar Series

Extrinsic regulation of haematopoietic stem cell self

UserSean J. Morrison Investigator, Howard Hughes Medical Institute.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 15 July 2014, 11:45-13:30

Centre for Molecular Science Informatics

Interacting with Protein Interactions

"Special Event" Cambridge Cheminformatics Network Meetings

UserProfessor Arthur J Olson, Departmen of Interactive Structure & Computational BIology, The Scripps Research Institute, La Jolla CA.

HousePfizer Lecture Theatre Department of Chemistry Lensfield Road Cambridge Cambridgeshire CB2 3RA.

ClockWednesday 09 July 2014, 16:00-17:00

MRC LMB Seminar Series

Milstein Lecture 2014: Unfolded Protein Response in Health and Disease

UserPeter Walter, University of California, San Francisco .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 30 June 2014, 16:15-18:00

MRC LMB Seminar Series

The function and execution of RTEL1 activities at vertebrate telomeres

UserDr Simon Boulton, DNA damage Response Laboratory, London Research Institute.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 27 June 2014, 16:15-18:00

MRC LMB Seminar Series

Exploring the final events in eukaryotic cell division

UserJuan Martin-Serrano, Kings College London.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 26 June 2014, 16:15-18:00

Centre for Molecular Science Informatics

Synergism between Theory and Experiments in Asymmetric Catalysis: Transition State Modeling for Rationalizations and Catalyst Design

UserProfessor Raghavan B. Sunoj, Department of Chemistry, Indian Institute of Technology, Bombay.

HouseUnilever Lecture Theatre, Department of Chemistry.

ClockThursday 19 June 2014, 14:15-15:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structures and mechanisms of macromolecular complexes involved in transcription and DNA repair

UserProfessor Xiaodong Zhang Imperial College London Department of Life Sciences.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 11 June 2014, 10:15-11:15

Centre for Molecular Science Informatics

"CADD & ENAC - A bad hand at Scrabble..?"

Please note that the date of this seminar has been changed

UserDr Peter Hunt, Optibrium Ltd.

HouseUnilever Lecture Theatre, Department of Chemistry.

ClockTuesday 03 June 2014, 14:15-15:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Crystal structure of the Drosophila Toll-SpΓ€tzle complex reveals neurotrophin-like binding specificity

UserMonique Gangloff, Biochemistry.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 28 May 2014, 10:15-11:15

MRC LMB Seminar Series

Engineering strategies for tuning cell surface receptor signalling

UserK. Christopher Garcia, Stanford University School of Medicine .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 14 May 2014, 16:15-18:00

Centre for Molecular Science Informatics

Visualization of Chemical Space for Medicinal Chemists

UserDr Peter Ertl, Novartis, Basel, Switzerland.

HouseUnilever Lecture Theatre, Department of Chemistry.

ClockTuesday 06 May 2014, 14:15-15:30

Centre for Molecular Science Informatics

"From fragments to target-selective ligands by reaction-driven de novo design"

UserProfessor Gisbert Schneider. Institute of Pharmaceutical Sciences ETH Zurich.

HousePfizer Lecture Theatre, Department of Chemistry.

ClockMonday 28 April 2014, 14:15-15:30

MRC LMB Seminar Series

Structural basis of protein PARylation-dependent ubiquitination

UserRachel Klevit, University of Washington.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 24 April 2014, 16:15-18:00

MRC LMB Seminar Series

Francis Crick Lecture 2014: Prions Causing Neurodegeneration: A Unifying Etiology and the Quest for Therapeutics

UserStanley Prusiner, University of California San Francisco .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 11 April 2014, 15:00-17:00

MRC LMB Seminar Series

What can NMR tell us about how a virus enters its host cell?

UserAd Bax, NIH.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 10 April 2014, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

How insulin binds to the insulin receptor: structural biology and protein engineering

UserDr Michael Weiss, School of Medicine Cleveland, USA.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 09 April 2014, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The Structure of the Large Subunit of the Yeast Mitochondrial Ribosome

UserDr Alan Brown.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 02 April 2014, 10:15-11:15

MRC LMB Seminar Series

Building proteins de novo: better, faster, fitter

UserDek Woolfson, University of Bristol.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 27 March 2014, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Coot's EM Model-fitting Tools

UserDr Paul Emsley, MRC-LMB, Cambridge, U.K..

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 26 March 2014, 10:15-11:15

MRC LMB Seminar Series

John Kendrew Lecture 2014: Birth and Future of Multi-Scale Modeling of Macromolecules

UserMichael Levitt, Standford Unversity.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 25 March 2014, 16:15-18:00

Centre for Molecular Science Informatics

Odorant space: From chemistry to physiology

UserDr Michael Schmuker, Neuroinformatics & Theoretical Neuroscience, Freie UniversitΓ€t Berlin.

HouseUnilever Lecture Theatre.

ClockTuesday 25 March 2014, 14:15-15:45

MRC LMB Seminar Series

microRNAs, circular RNAs, and micropeptides

UserProfessor Nikolaus Rajewsky, Max DelbrΓΌck Center for Molecular Medicine, Berlin.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 24 March 2014, 15:00-16:15

MRC LMB Seminar Series

Type VI Secretion System: structure, function and dynamics of a multicomponent nanomachine that is evolutionarily related to a contractile phage tail

UserMarek Basler, University of Basel.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 26 February 2014, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Small Angle X-ray Scattering: sample preparation, data collection, and data analysis.

UserDr Meindert Lamers, MRC-LMB, Cambridge, U.K.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 26 February 2014, 10:15-11:15

Centre for Molecular Science Informatics

Protein-Ligand Binding by Free Energy Simulations: Issues, Successes and Failures

Please note the change of date, one week earlier than originally planned

UserProfessor Jonathan Essex, University of Southampton.

HouseUnilever Lecture Theatre.

ClockTuesday 25 February 2014, 14:15-15:45

Structural Biology group talks at Biochemistry

The extracellular lysine residues of in vitro folded neuropeptide receptor type 2 interacting with its ligand observed by > NMR spectroscopy

UserDr Sandra Berndt, Nietlispach lab, Biochemistry Dept.

HouseDepartment of Biochemistry, Sanger building, Seminar Room.

ClockWednesday 12 February 2014, 10:15-10:45

Structural Biology group talks at Biochemistry

Targeting Ubiquitin chains with Deubiquitinases

UserDr Yu Ye, Klenerman lab, Chemistry Dept.

HouseDepartment of Biochemistry, Sanger building, Seminar Room.

ClockWednesday 12 February 2014, 10:15-10:45

MRC LMB Seminar Series

Lighting up RNA Interactions in Living Cells

UserDavid Tollervey, WTCCB, University of Edinburgh.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 10 February 2014, 14:00-15:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Cyclofluidic: Quick hit-to-lead optimization using an integrated microfluidic approach

UserDr Ronald Dorenbos, Business Development Director Europe Cyclofluidic Ltd..

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 05 February 2014, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Title to be confirmed

UserPaula de Fonseca - LMB.

HouseBiochemistry Seminar Room, Sanger Building.

ClockTuesday 28 January 2014, 10:15-11:30

MRC LMB Seminar Series

Feldberg Prize Lecture: The mitochondrial machinery for transport and assembly of proteins

UserKlaus Pfanner, University of Freiburg.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 23 January 2014, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Using evolutionary sequence variation to make inferences about protein structure and function

UserLucy J. Colwell, Department of Chemistry, University of Cambridge.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 22 January 2014, 10:15-11:15

MRC LMB Seminar Series

Systematic cell biology - Moving beyond text-book schemes

UserMaya Schuldiner, The Weizmann Insitute of Science.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 09 January 2014, 14:00-15:00

MRC LMB Seminar Series

GPCRs: From thermostabilisation to X-ray structures and Drug discovery

UserFiona Marshall, Heptares Therapeutics.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 12 December 2013, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Protein-Protein Interaction Networks and Diseases

UserFranca Fraternali, Randall Division of Cell and Molecular Biophysics, King's College London, UK .

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 27 November 2013, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Analysis of allosteric communication and functional local motions using a Structural Alphabe

UserAlessandro Pandini,Randall Division of Cell and Molecular Biophysics,King's College London, UK .

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 27 November 2013, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Chirality as a crossroad of chemistry and biology

UserProfessor Reiko KURODA, Tokyo University of Science (Japan).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 13 November 2013, 10:15-11:15

MRC LMB Seminar Series

Brain Power: Where does it come from and how is it used?

UserProfessor David Attwell, University College London.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 07 November 2013, 17:00-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Title to be confirmed

UserShaoxia Chen, MRC-LMB, cambridge.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 06 November 2013, 10:15-11:15

MRC LMB Seminar Series

John Kendrew Lecture 2013: Noncoding RNAs: with a viral twist

UserJoan Steitz, Yale University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 01 November 2013, 16:15-18:00

MRC LMB Seminar Series

Embracing Complexity: A Drosophila Approach To Cancer Therapeutics

UserRoss Cagan, Mt. Sinai School of Medicine.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 31 October 2013, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Evolution & dynamics of protein complexes

UserSarah Teichmann, Wellcome Trust Sanger Institute.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 30 October 2013, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Crystallisation and structure of respiratory complex I, a giant molecular proton pump

UserLeonid Sazanov, MRC Mitochondrial Biology Unit, Wellcome Trust / MRC Building, cambridge.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 23 October 2013, 10:15-11:15

Centre for Molecular Science Informatics

Protein-Ligand Binding by Free Energy Simulations: Issues, Successes and Failures

We regret that due to illness this talk has been cancelled

UserProfessor Jonathan Essex, University of Southampton.

HouseUnilever Lecture Theatre.

ClockTuesday 15 October 2013, 12:00-13:30

MRC LMB Seminar Series

Can structural studies of intact viruses really be useful in the search for better vaccines and antivirals?

UserDavid Stuart, University of Oxford.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 10 October 2013, 16:15-18:00

Centre for Molecular Science Informatics

"Global Protein Structural Analysis for Drug Discovery"

UserDr Krishna Bulusu, from the Institute of Cancer Research (ICR).

HouseTodd Hamied Room, Department of Chemistry.

ClockTuesday 08 October 2013, 14:15-15:45

MRC LMB Seminar Series

Conformational Conversion in Amyloid Assembly

UserSheena Radford, University of Leeds.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 03 October 2013, 16:15-18:00

MRC LMB Seminar Series

Milstein Lecture 2013: Sorting out protein traffic: Ubiquitin-mediated endocytosis and a membrane protien’s final ESCRT

UserScott Emr, Cornell University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 26 September 2013, 16:15-18:00

MRC LMB Seminar Series

Innate Immune Sensing and Signaling of Cytosolic DNA and RNA

UserZhijan 'James' Chen, University of Texas Southwestern Medical Center.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 24 September 2013, 16:15-18:00

MRC LMB Seminar Series

Long-distance organelle transport in the neuron: mechanisms of motor engagement and motor coordination

UserErika Holzbaur, University of Pennyslvania.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 05 September 2013, 16:15-18:00

MRC LMB Seminar Series

The Evolutionary 'Design' of Proteins

UserRama Ranganathan, UT Southwestern Medical Centre.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 04 September 2013, 11:00-12:00

Centre for Molecular Science Informatics

On the importance of the COSMO polarization charge density for the quantification of molecular interactions in liquid phases

UserProf. Dr. Andreas Klamt, COSMOlogic GmbH & Co. KG.

HouseUnilever Lecture Theatre.

ClockWednesday 28 August 2013, 15:00-16:30

MRC LMB Seminar Series

Watching Individual Proteins Working on Single Molecules of DNA: from Biophysics to Cancer

UserSteve Kowalczykowski, University of California.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 09 August 2013, 16:15-18:00

MRC LMB Seminar Series

Biological insights from cryo-EM studies of complex macromolecular assemblies in transcription initiation and microtubule dynamics

UserEva Nogales, HHMI University of California Berkely.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 24 July 2013, 16:15-18:00

MRC LMB Seminar Series

The impact of systemic inflammation on the brain in health and disease

UserHugh Perry, University of Southampton.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 27 June 2013, 16:15-18:00

MRC LMB Seminar Series

Intrinsic biophysical diversity and connectivity of neuronal circuits

UserTroy Margrie, NIMR.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 11 June 2013, 17:00-18:00

Centre for Molecular Science Informatics

Approaching protein dynamics in the post-genome era

UserProfessor Modesto Orozco, Dept. Biochemistry & Molecular Biology, University of Barcelona .

HouseUnilever Lecture Theatre.

ClockTuesday 11 June 2013, 14:15-15:30

MRC LMB Seminar Series

Direct Selection for Antibodies that Control Cell Fates from Intracellular Combinatorial Antibody Libraries

UserProfessor Richard Lerner, The Scripps Research Institute, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 05 June 2013, 12:00-13:00

Centre for Molecular Science Informatics

"Molecular Dynamics Simulations of the Influenza Virus Envelope: Complex Interplay between Membrane Proteins and Lipid Domains"

UserDr Daniel Parton, Sloan Kettering Institute, New York.

HouseUnilever Lecture Theatre.

ClockWednesday 29 May 2013, 14:15-15:30

Centre for Molecular Science Informatics

Calculations on Tunneling by Carbon Tell Experimentalists Where to Look and What to Look For

UserProfessor Wes Borden, Unversity of Texas.

HouseUnilever Lecture Theatre.

ClockTuesday 28 May 2013, 14:15-15:30

Centre for Molecular Science Informatics

Why Does Cyclobutane-1,2,3,4-tetraone Have a Triplet Ground State?

A TMI RIG Presentation

UserProfessor Wes Borden, Unversity of Texas.

HousePfizer Lecture Theatre, Department of Chemistry.

ClockWednesday 22 May 2013, 14:15-15:30

Centre for Molecular Science Informatics

"Using computational methods to aid our understanding of ionotropic glutamate receptors at the molecular level"

UserDr Phil Biggin, Department of Biochemistry, University of Oxford.

HouseUnilever Lecture Theatre.

ClockTuesday 21 May 2013, 14:15-15:30

MRC LMB Seminar Series

Cytoskeletal Control of Leukocyte Chemotaxis

UserMichael Sixt, IST Austria.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 13 May 2013, 16:15-18:00

MRC LMB Seminar Series

Selective autophagy: when being picky pays of

UserAna-Maria Cuervo, Albert Einstein College of Medicine .

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 02 May 2013, 16:15-18:00

MRC LMB Seminar Series

Max Perutz Lecture: Five ways that viruses use to enter the animal cell

UserProfessor Ari Helenius, ETH Zurich, Switzerland.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 30 April 2013, 14:30-15:30

Centre for Molecular Science Informatics

Enzyme dynamics, conformations and catalysis

UserProfessor Adrian Mulholland, Centre for Computational Chemistry, Univeristy of Bristol.

HouseUnilever Lecture Theatre.

ClockTuesday 30 April 2013, 14:15-15:30

MRC LMB Seminar Series

Machinery for making coated vesicles

UserMargaret Scott Robinson, CIMR.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 16 April 2013, 16:15-18:00

MRC LMB Seminar Series

The genetics of individuals: why would a mutation kill me, but not you?

UserBen Lehner, CRG Barcelona.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 09 April 2013, 15:00-16:00

MRC LMB Seminar Series

The mammalian circadian timing system: how the brain communicates with the periphery

UserUeli Schibler, University of Geneva.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 27 March 2013, 12:00-13:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Probing dynamic conformational changes in lipid signalling using hydrogen deuterium exchangemass spectrometry

UserDr John Burke, LMB, Cambridge U.K.

HousePerham's seminar room.

ClockWednesday 27 March 2013, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Open Source Drug Discovery:Β  Developing a Systems LevelΒ Translational Platform for Neglected Diseases

UserProf. Samir K. Brahmachari, Founder Director, Institute of Genomics and Integrative Biology,Β  Director General, Council of Scientific & Industrial Research,Β  Delhi, India.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockFriday 22 March 2013, 13:00-14:00

Structural Biology group talks at Biochemistry

Come and meet the Monster: a work in progress on human Rad51 oligomeric structure ("the Monster") and its potential relevance for DNA Repair and drug design.

UserTommaso Moschetti (Hyvonen Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 19 March 2013, 16:00-17:00

Structural Biology group talks at Biochemistry

Single molecule imaging reveals that CENP-A deposition occurs during G2 in fission yeast

UserDavid Lando (Laue Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 19 March 2013, 16:00-17:00

Structural Biology group talks at Biochemistry

New Developments at Diamond Light Source and the use of Free Electron Lasers in structural biology

UserSteven Hardwick & Jarrod Voss (Luisi Group) .

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 05 March 2013, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

PHASER workshop

UserAirlie McCoy, CIMR, University of Cambridge.

HousePerham's seminar room.

ClockWednesday 27 February 2013, 10:15-11:15

Centre for Molecular Science Informatics

β€œData Driven Molecular Design & Discovery”

UserDr Scott Lusher, Netherlands eScience Centre.

HouseUnilever Lecture Theatre.

ClockThursday 21 February 2013, 11:00-12:00

Structural Biology group talks at Biochemistry

Assembly of a protein-RNA bacterial suicide complex

UserFrancesca Short (Salmond Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 19 February 2013, 16:00-17:00

Structural Biology group talks at Biochemistry

Mechanisms of extracellular regulation of TGFΞ² superfamily: protein engineering and interaction analysis

UserCat Donaldson (Hyvonen Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 19 February 2013, 16:00-17:00

Centre for Molecular Science Informatics

"Thinking (and looking) out of the box - new tricks for molecular simulation and visualization"

UserDr Marc Baaden, Institut de Biologie Physico-Chimque, Paris.

HouseUnilever Lecture Theatre.

ClockTuesday 19 February 2013, 14:15-15:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

OPPF-UK: a national resource centre for protein production.

UserDr Louise Bird, OPPF, UK.

HousePerham's seminar room.

ClockWednesday 13 February 2013, 10:15-11:15

Structural Biology group talks at Biochemistry

Snaphshots of Membrane Proteins at Work

UserSimone Weyand (Lummis Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 05 February 2013, 16:00-17:00

Structural Biology group talks at Biochemistry

The role of the acidic tail in HMGB proteins: a combined NMR and SAXS approach

UserKatherine Stott (Thomas Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 05 February 2013, 16:00-17:00

Structural Biology group talks at Biochemistry

Specificity in the Ubiquitin System

UserDavid Komander (LMB).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 22 January 2013, 16:00-17:00

MRC LMB Seminar Series

Assembly and Dynamics of Uber Complex RNPs

UserMelissa Moore, University of Massachusetts Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 03 December 2012, 16:15-18:00

Structural Biology group talks at Biochemistry

Dissecting Fragment-Based Lead Discovery at the von Hippel Lindau protein:Hypoxia Inducible Factor-1alpha Interface

UserInge van Molle (Ciulli Group, Chemistry).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 27 November 2012, 16:00-17:00

Structural Biology group talks at Biochemistry

The Discovery of Novel Sialidase Inhibitors

UserPaul Brear (Hyvonen Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 27 November 2012, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

AnchorQuery: Interactive and efficient discovery tool of small molecule protein-protein interaction antagonists

UserCarlos Carmachio.

HousePerham's seminar room.

ClockWednesday 21 November 2012, 10:15-11:15

Structural Biology group talks at Biochemistry

Catalytic Promiscuity in the Alkaline Phosphatase Superfamily

UserBert van Loo (FH Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 13 November 2012, 15:45-16:45

Structural Biology group talks at Biochemistry

Label-free Study of Chromatin Architecture in Living Organisms using Stimulated Raman Scattering Microscopy

UserSrinjan Basu (EDL Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 13 November 2012, 15:45-16:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Identifying hot-spots and designing small molecule inhibitors at protein-protein interfaces: taking advantage of bound water networks

UserDr David J. Huggins, Department of Oncology Hutchison/MRC Research Centre.

HousePerham's seminar room.

ClockWednesday 07 November 2012, 10:15-11:15

Structural Biology group talks at Biochemistry

Replication Initiation: Focus on the Components of the Pre-initiation Complex

UserOleg Kovalevskiy (Zegerman Group, Gurdon).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 30 October 2012, 15:45-16:45

Structural Biology group talks at Biochemistry

The Structural Basis of Z Alpha-1-antitrypsin Deficiency

UserTim Sendall (HM/DO Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 30 October 2012, 15:45-16:45

Centre for Molecular Science Informatics

"The mechanisms of solute flux through membrane channels from multi-microsecond equilibrium simulations"

UserDr Martin Ulmschneider, Dept. of Biological Sciences, Birkbeck College, University of London.

HouseUnilever Lecture Theatre.

ClockTuesday 30 October 2012, 14:15-15:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The importance of thermostability and its application to the structure determination of GPCRs

UserDr Chris Tate, LMB.

HousePerham's seminar room.

ClockWednesday 24 October 2012, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

X-ray diffraction data reduction: space group determination, scaling and intensity statistics

UserDr Phil Evans, FRS, LMB.

HousePerham's seminar room.

ClockWednesday 10 October 2012, 10:15-11:15

Structural Biology group talks at Biochemistry

PHD Zinc Fingers in Chromatin-Associated Proteins

UserCynthia Tallant-Blanco (Cuilli Group, Chemistry).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 09 October 2012, 15:45-16:45

Structural Biology group talks at Biochemistry

NMR Applications to Large Systems: Sensory Rhodopsin II, Membrane Mimics and Fast NMR

UserMark Bostock (DN Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 09 October 2012, 15:45-16:45

Structural Biology group talks at Biochemistry

The Structures of Whole Chromosomes in Individual Cells

UserTim Stevens (EDL Group).

HouseBiochemistry Seminar Room, Sanger Building.

ClockTuesday 18 September 2012, 16:00-17:00

MRC LMB Seminar Series

New insights into the role of the chromatin associated factor ATRX

UserDoug Higgs, MRC Molecular Haematology Unit, Oxford.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 17 September 2012, 11:30-13:00

MRC LMB Seminar Series

Max Perutz Lecture 2012: Defective DNA strand break repair, genome instability and cancer

UserSteve West, CRUK LRI - Clare Hall.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 13 September 2012, 16:15-18:00

MRC LMB Seminar Series

Lgr5 Stem Cells in self-renewal and cancer

Joint lecture with CRI and MRC LMB

UserHans Clevers, Hubrecht Institute.

HouseCambridge Research Institute.

ClockTuesday 11 September 2012, 13:00-14:30

Centre for Molecular Science Informatics

Successes and challenges in the prediction of P450 mediated drug metabolism

UserProfessor Patrik Rydberg, University of Copenhagen, Department of Drug Design and Pharmacology.

HouseUnilever Lecture Theatre.

ClockTuesday 04 September 2012, 14:00-15:30

MRC LMB Seminar Series

Normal and neoplastic stem cells

UserIrving Weissman, Stanford School of Medicine.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 11 July 2012, 16:15-18:00

Centre for Molecular Science Informatics

"Entropy and order parameters from ensembles generated by computer simulations"

UserProfressor Klaus Liedl, University of Innsbruck.

HouseUnilever Lecture Theatre.

ClockWednesday 27 June 2012, 15:15-16:30

MRC LMB Seminar Series

Mechanisms for the Selective Degradation of Ubiquitinated Proteins by the 26S Proteasome

UserFred Goldberg, Harvard Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 22 June 2012, 16:15-18:00

Centre for Molecular Science Informatics

"Dynamics of Biomolecules: from the Glass Transition to Drug Design"

A joint Theory/UCC talk as part of the TMI Research Interest Group

UserProfessor Jeremy C Smith, Oak Ridge National Laboratory.

HousePfizer Lecture Theatre, Dept. of Chemistry.

ClockWednesday 20 June 2012, 14:15-15:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Title to be confirmed

UserHelen Saibil.

HousePerham's seminar room.

ClockWednesday 13 June 2012, 10:15-11:15

MRC LMB Seminar Series

Shedding light on Ubiquitin Modification in Cancer.

UserVishva Dixit, Genentech.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 12 June 2012, 16:15-18:00

Structural Biology group talks at Biochemistry

Crystal Structure of Folliculin Uncovers a HiDENN Function

UserRavi Nookala (TLB Group).

HouseBiochemistry Seminar Room, Sanger Building.

ClockTuesday 12 June 2012, 16:00-17:00

MRC LMB Seminar Series

The structural and mechanistic basis for Rab cycling and targeting

UserRoger Goody, MPI Dortmund.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 21 May 2012, 16:15-18:00

MRC LMB Seminar Series

Milstein Lecture 2012: How do we sense microbes? From LPS, TNF, and the TLRs.

UserBruce Beutler, UT Southwestern Medical Centre.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 17 May 2012, 16:15-18:00

MRC LMB Seminar Series

Monitoring protein synthesis one codon at a time through ribosome profiling

UserJonathan Weissman, Howard Hughes Medical Institute, UCSF.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 10 May 2012, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structural studies of chromosome segregation

UserMartin Singleton.

HousePerham's seminar room.

ClockWednesday 02 May 2012, 10:15-11:15

MRC LMB Seminar Series

Local Translation at the Synapse

UserErin Schuman, Max Planck Institute.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 30 April 2012, 16:15-18:00

MRC LMB Seminar Series

How end binding proteins recognise growing microtubule ends: from molecular structure to network functioning

UserThomas Surrey, Cancer Research UK, London Research Institute.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 26 April 2012, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

SAXS studies on biological molecules at Diamond Light Source

UserInoue Katsuaki, DLS, UK.

HousePerham's seminar room.

ClockWednesday 25 April 2012, 10:15-11:15

MRC LMB Seminar Series

Molecular mechanisms of complement activation and regulation

UserPiet Gros, Utrecht University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 19 April 2012, 14:00-16:00

MRC LMB Seminar Series

Ubiquitin flips the anaphase switch

UserDavid Morgan, UCSF.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 13 April 2012, 16:15-18:00

MRC LMB Seminar Series

John Kendrew Lecture 2012: Harnessing actin dynamics for endocytic trafficking events

UserDavid Drubin, Berkeley.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 03 April 2012, 16:15-18:00

Structural Biology group talks at Biochemistry

Structural studies of HAT1 and its binding partners

UserIan Le Guillou (EDL).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 20 March 2012, 16:00-17:00

Structural Biology group talks at Biochemistry

Allosteric Regulation and Assembly of Glutamate Receptor Ion Channels.

UserMaxim Rossmann (MH).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 20 March 2012, 16:00-17:00

Structural Biology group talks at Biochemistry

David Lando Talk

UserDavid Lando (Laue Group).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockMonday 19 March 2012, 16:00-17:00

MRC LMB Seminar Series

A Chemicogenetic approach to DNA repair implicates TORC2 and actin in survival of DNA breaks

UserSusan Gasser, Friedrich Miescher Institute for Biomedical Research.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 12 March 2012, 16:15-18:00

MRC LMB Seminar Series

Disruptions on the Highways of Cell Communication

UserDario Alessi, MRC Protein Phosphorylation Unit, University of Dundee.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 06 March 2012, 16:15-18:00

Structural Biology group talks at Biochemistry

From protein interactions to gene expression distributions

UserSarah Teichmann (LMB).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 06 March 2012, 16:00-17:00

MRC LMB Seminar Series

Structural and Biochemical Mechanisms of Synchronous Synaptic Transmission

UserJames Rothman, Yale University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 21 February 2012, 11:30-18:00

MRC LMB Seminar Series

Crick Lecture 2012: Consequences of Aneuploidy

UserAngelika Amon, HHMI, MIT.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 15 February 2012, 16:15-18:00

Structural Biology group talks at Biochemistry

Solid-State NMR Investigations of Membrane Bound Ras Proteins and Y2 G Protein-Coupled Receptors

UserProf. Daniel Huster. Institute for Medical Physics and Biophysics, University of Leipzig.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 14 February 2012, 16:00-17:00

MRC LMB Seminar Series

New concepts in host-pathogen interactions: lessons from Listeria

UserPascale Cossart, Institute Pasteur, Paris.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 02 February 2012, 16:15-18:00

Centre for Molecular Science Informatics

Lessons from Yeast: Drug Uptake and Systems Biology

UserDr Paul D Dobson, Department of Chemical & Biological Engineering, University of Sheffield.

HouseUnilever Lecture Theatre.

ClockTuesday 31 January 2012, 14:00-15:30

Structural Biology group talks at Biochemistry

Structural Biology facilities - Updates and Discussion Session

UserDima Chirgadze, Katherine Stott.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 24 January 2012, 16:00-17:00

MRC LMB Seminar Series

Functions of Dynamin A, Myosin IB and WASH in phagolysosome biogenesis, and the Exocyst in kiss-and-run exocytosis in Dictyostelium

UserThierry Soldati, University of Geneva.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 23 January 2012, 16:15-18:00

Structural Biology group talks at Biochemistry

A Study of the Human Primase: Initiator of DNA Replication

UserMairi Kilkenny (LP).

HouseBiochemistry Seminar Room, Sanger Building.

ClockTuesday 10 January 2012, 16:00-17:00

Structural Biology group talks at Biochemistry

Relating structure to function in natural surfactant proteins.

UserSteve Vance (RWB).

HouseBiochemistry Seminar Room, Sanger Building.

ClockTuesday 10 January 2012, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Domain swapping in proteins

UserDr Sowdhamini, National Centre for Biological Sciences (TIFR) UAS-GKVK Campus Bellary Road Bangalore 560 065 INDIA.

HousePerham's seminar room.

ClockWednesday 21 December 2011, 10:15-11:15

MRC LMB Seminar Series

Signaling through the ubiquitin system

UserWade Harper, Harvard Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 15 December 2011, 16:15-18:00

Journal Clubs

Journal Club

UserHeather (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 12 December 2011, 10:55-11:15

Journal Clubs

Journal Club

UserAngela (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 12 December 2011, 10:35-10:55

Journal Clubs

Journal Club

UserSandra (MH).

HouseSeminar Room, Sanger Building.

ClockMonday 12 December 2011, 10:15-10:35

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

To be confirmed

UserDr Bissan Al-Lazikani, Computational Biology and Chemogenomics Institute of Cancer Research, U.K.

HousePerham's seminar room.

ClockWednesday 07 December 2011, 10:15-11:15

Structural Biology group talks at Biochemistry

FKBP - a structure without a cause?

UserChristian Edlich (EDL).

HouseBiochemistry Seminar Room, Sanger Building.

ClockTuesday 06 December 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

Model interaction systems in the search for inhibitors of protein-protein interactions

UserSandra Greive (MH).

HouseBiochemistry Seminar Room, Sanger Building.

ClockTuesday 06 December 2011, 16:00-17:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Low Resolution Crystallography

UserDr Dima Chirgadze, Biochemistry Department, University of Cambridge.

HousePerham's seminar room.

ClockWednesday 30 November 2011, 10:15-11:15

Structural Biology group talks at Biochemistry

Zinc fingers reading signals

UserDavid Neuhaus (LMB).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 29 November 2011, 16:00-17:00

MRC LMB Seminar Series

Structural and Mechanistic Studies of the Anaphase Promoting Complex

UserDavid Barford, Institute of Cancer Research.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 24 November 2011, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Making candy for signal transduction research - Adventures in Willy Wonka land

UserProf Morten GrΓΆtli, Department of Chemistry, University of Gothenburg.

HousePerham's seminar room.

ClockThursday 24 November 2011, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Low resolution refinement tools in the program REFMAC

UserDr Garib N Murshudov, LMB, MRC, Cambridge, U.K.

HousePerham's seminar room.

ClockWednesday 23 November 2011, 10:15-11:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Fuzzy complexes: ambiguity in protein-protein and protein-DNA interactions

UserProfessor Monika Fuxreiter Institute of Enzymology, Budapest, HUNGARY and LMB, MRC, Cambridge, UK.

HousePerham's seminar room.

ClockWednesday 16 November 2011, 10:15-11:15

MRC LMB Seminar Series

The Evolution of Enzyme Mechanisms and Functional Diversity

UserJanet Thornton, EMBL-EBI.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 15 November 2011, 16:15-18:00

Structural Biology group talks at Biochemistry

A Bayesian view on cryo-EM structure determination

UserSjors Scheres (LMB).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 15 November 2011, 16:00-17:00

Journal Clubs

Journal Club

UserCat (MH).

HouseSeminar Room, Sanger Building.

ClockMonday 14 November 2011, 10:55-11:15

Journal Clubs

Journal Club

UserSteven (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 14 November 2011, 10:35-10:55

Journal Clubs

Journal Club

UserRavi (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 14 November 2011, 10:15-10:35

Structural Biology group talks at Biochemistry

Structural and interaction studies of domain C0 of cardiac Myosin Binding Protein C (cMyBP-C) by NMR spectroscopy

UserJoyce Ratti (NM).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 01 November 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

At the Frontier of Membrane Protein Crystallography: The Structure of Yeast Aquaporin to 0.9 Γ… at Cryogenic and 1.3 Γ… at Room Temperature.

UserGerhard Fischer (University of Gothenburg, Sweden).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 01 November 2011, 16:00-17:00

MRC LMB Seminar Series

Structural Studies on the Regulation of Protein Kinases: EGFR and CamK-II

UserJohn Kuriyan, HHMI, University of California, Berkeley.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 31 October 2011, 16:15-18:00

MRC LMB Seminar Series

Neuronal plasticity: from synapses to the axon initial segment

UserJuan Burrone, Kings College London.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 28 October 2011, 16:15-18:00

MRC LMB Seminar Series

DNA-dependent protein kinase is a DNA sensor for IRF-3-dependent innate immunity

UserGeoffrey Smith, Department of Pathology Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 06 October 2011, 16:15-18:00

MRC LMB Seminar Series

mRNA-tRNA translocation intermediates by cryo-EM: a look at the free-energy landscape from a single sample.

UserJoachim Frank, Columbia University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 30 September 2011, 16:15-18:00

Centre for Molecular Science Informatics

"New Developments in Semiempirical MO Theory for Drug and Materials Design"

This Lecture is part of Professor Clark's MGMS Lecture tour

UserProfessor Tim Clark, Friedrich-Alexander-UniversitΓ€t Erlangen-NΓΌrnberg, Germany.

HousePfizer Lecture Theatre, Dept. of Chemistry.

ClockThursday 22 September 2011, 14:00-15:30

MRC LMB Seminar Series

Molecular and cellular mechanisms for memory allocation in neuronal networks

UserAlcino Silva, UCLA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 16 September 2011, 16:15-18:00

MRC LMB Seminar Series

Genetic dissection of emotion circuits in flies and mice - Francis Crick Lecture 2011

UserDr David Anderson, California Institute of Technology, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 09 September 2011, 16:00-18:00

Structural Biology group talks at Biochemistry

Most recent development in crystalisation optimization and shotgun diffraction

UserProfessor Seth Fraden, Brandeis University,Waltham, MA, USA.

HouseSeminar Room, Sanger Building.

ClockFriday 29 July 2011, 14:00-15:00

Structural Biology group talks at Biochemistry

Snapshots of the membrane protein Mhp1 at work

UserDr Simone Weyand, Imperial College.

HouseSeminar Room, Sanger Building.

ClockFriday 29 July 2011, 12:00-13:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structural complexomics of eukaryotic gene expression.

UserDr Imre Berger, EMBL, Grenoble, France.

HouseSeminar Room, Sanger Building.

ClockWednesday 27 July 2011, 10:15-11:00

MRC LMB Seminar Series

Self-assembled DNA-nanostructure tools for molecular biophysics

UserWilliam Shih, Harvard Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 25 July 2011, 16:15-18:00

MRC LMB Seminar Series

PDBe - Bringing Structure to Biology

UserGerard Kleywegt, EMBL-EBI.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 14 July 2011, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Receptor-based Drug Discovery

User Dr Jiye Shi, UCB Celltech.

HouseSeminar Room, Sanger Building.

ClockWednesday 13 July 2011, 10:15-11:00

MRC LMB Seminar Series

Tuberculosis Treatment Dicta from the Zebrafish

UserLalita Ramakrishnan, University of Washington.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 07 July 2011, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Probing protein-ligand recognition mechanisms with isothermal titration calorimetry

UserDr Mark Williams. Birkbeck College.

HouseRoom 2, Stem Cell Research Centre.

ClockWednesday 06 July 2011, 11:00-12:00

Structural Biology group talks at Biochemistry

"Structural Basis of the Regulation of Chromosome Segregation and Mitosis Progression"

UserVictor Bolanos-Garcia (TLB group).

HouseSeminar Room, Sanger Building.

ClockTuesday 28 June 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"A new structural genomics: the structures of whole chromosomes"

UserTim Stevens (EDL).

HouseSeminar Room, Sanger Building.

ClockTuesday 28 June 2011, 16:00-17:00

MRC LMB Seminar Series

Autoantibodies against NMDA receptors and other neuronal targets: the widening spectrum of antibody-mediated CNS disorders

UserAngela Vincent, University of Oxford.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 22 June 2011, 14:30-16:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Crystal dehydration: Experimental design with a home source and at the synchroton

User Dr Juan Sanchez Weatherby: Diamond, UK.

HouseSeminar Room, Sanger Building.

ClockWednesday 22 June 2011, 10:15-11:00

Structural Biology group talks at Biochemistry

"Structure of a motor-driven restriction-modification enzyme bound to its target DNA"

UserSaikrishnan Kayarat (LMB).

HouseSeminar Room, Sanger Building.

ClockTuesday 21 June 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"Structure-function studies of the archaeal HR nuclease NurA"

UserNeil Rzechorzek (LP group).

HouseSeminar Room, Sanger Building.

ClockTuesday 21 June 2011, 16:00-17:00

MRC LMB Seminar Series

Exploring and exploiting chromosome repair and segregation mechanisms in cancer

UserAshok Venkitaraman, MRC Cancer Cell Unit.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 16 June 2011, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Designing Bioactive Molecules and Mode-of-Action Analyses - The Benefits of Learning From the Past.

UserDr Andreas Bender, Unilever Centre, Cambridge.

HouseSeminar Room, Sanger Building.

ClockWednesday 15 June 2011, 10:15-11:00

Structural Biology group talks at Biochemistry

Determining structures with NMR - the CcpNmr Analysis program

UserRasmus Fogh (EDL Group).

HouseSeminar Room, Sanger Building.

ClockTuesday 07 June 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"DNA Polymerase alpha at work: Understanding the Mechanism"

UserRajika Perera (LP group).

HouseSeminar Room, Sanger Building.

ClockTuesday 07 June 2011, 16:00-17:00

MRC LMB Seminar Series

Visualizing vesicle and virus budding by electron microscopy

UserJohn Briggs, EMBL.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 01 June 2011, 11:30-13:15

MRC LMB Seminar Series

Genetic Architecture of Leukaemia

UserMel Greaves, Institute of Cancer Research.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 19 May 2011, 16:15-18:00

Centre for Molecular Science Informatics

Exploring free-energy landscapes

UserProfessor Daan Frenkel FRS, Cambridge University Centre for Computational Chemistry, Department of Chemistry.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockThursday 19 May 2011, 15:30-16:30

Centre for Molecular Science Informatics

The power of coarse-graining in biomolecular simulations

UserProfessor Siewert-Jan Marrink, Groningen Biomolecular Sciences and Biotechnology Institute.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockThursday 19 May 2011, 14:00-15:30

Centre for Molecular Science Informatics

"Manipulating dynamics: Galilean-invariant friction and stochastic thermostats"

UserProfessor Herman Berendsen, Groningen Biomolecular Sciences and Biotechnology Institute.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockWednesday 18 May 2011, 14:00-15:30

MRC LMB Seminar Series

Delivery Boy to Reporter: Unusual DNA’s journey through a worm-whole

UserYamuna Krishnan, National Centre for Biological Sciences Bangalore.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 17 May 2011, 16:15-18:00

Structural Biology group talks at Biochemistry

"Chromatin Assembly Factor 1: Working with protein complexes"

UserNikki Royle (EDL group).

HouseSeminar Room, Sanger Building.

ClockTuesday 17 May 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"Structural studies of non-coding RNA mediated gene silencing in E. coli"

UserKasia Bandyra (BL group).

HouseSeminar Room, Sanger Building.

ClockTuesday 17 May 2011, 16:00-17:00

Centre for Molecular Science Informatics

"Molecular dynamics beyond molecules: principles for coarse-graining"

UserProfessor Herman Berendsen, Groningen Biomolecular Sciences and Biotechnology Institute.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 17 May 2011, 14:00-15:30

MRC LMB Seminar Series

A primer on DNA origami and why molecular biologists might care

UserHendrik Dietz, TU Munich.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 12 May 2011, 16:15-18:00

Structural Biology group talks at Biochemistry

"Mimicking the membrane; micelles, bicelles and nanodiscs"

UserMark Bostock (DN group).

HouseSeminar Room, Sanger Building.

ClockTuesday 10 May 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"Do very similar proteins fold in very similar ways?"

UserTim Sharpe (MH group).

HouseSeminar Room, Sanger Building.

ClockTuesday 10 May 2011, 16:00-17:00

MRC LMB Seminar Series

Genome-wide analysis of AID activity and AID-mediated translocations in B lymphocytes

UserRafael Casellas, NIH.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 06 May 2011, 16:15-18:00

MRC LMB Seminar Series

Feldberg Prize Lecture: Biogenesis of iron-sulfur proteins in eukaryotes

UserProfessor Roland Lill, Philipps University Marburg, Germany.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 15 April 2011, 16:15-18:00

MRC LMB Seminar Series

Controlling Recombination

UserSimon Boulton, CRUK Clare Hall Laboratories.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 14 April 2011, 16:15-18:00

MRC LMB Seminar Series

A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae

UserAnne-Claude Gavin, EMBL.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 12 April 2011, 16:15-18:00

Structural Biology group talks at Biochemistry

"Using high throughput simulation to understand signalling processes"

UserBenjamin Hall (University of Oxford).

HouseSeminar Room, Sanger Building.

ClockTuesday 12 April 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"Structure of RLIP76’s GTPase activating (GAP) and Ral binding domains (RBD) in solution"

UserKarthik Rajasekar (HRM-DO group).

HouseSeminar Room, Sanger Building.

ClockTuesday 12 April 2011, 16:00-17:00

MRC LMB Seminar Series

Milstein Lecture 2011: How the endoplasmic reticulum gets into shape

UserTom Rapoport, Harvard Medical School.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 07 April 2011, 16:15-18:00

MRC LMB Seminar Series

The Chemical Biology of Large-Scale Transcriptome Analysis

UserKevin Weeks, University of North Carolina.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 06 April 2011, 11:30-13:15

MRC LMB Seminar Series

The Cellular Basis for the Cancer-Related Phenomena of Immune Suppression and Cachexia

UserDoug Fearon.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 31 March 2011, 16:15-18:00

Structural Biology group talks at Biochemistry

"Super-resolution imaging in pombe"

UserDavid Lando (EDL Group).

HouseSeminar Room, Sanger Building.

ClockTuesday 29 March 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"Structural studies of a human non-homologous end-joing protein complex: DNA ligaseIV/XRCC4"

UserTakashi Ochi (TLB group).

HouseSeminar Room, Sanger Building.

ClockTuesday 29 March 2011, 16:00-17:00

MRC LMB Seminar Series

The Female Side of Fertilization: Crystal Structure of Vertebrate Sperm Receptor ZP3

UserLuca Jovine, Karolinska Institute.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 28 March 2011, 16:15-18:00

MRC LMB Seminar Series

The Structural Basis of Ubiquitin Signalling

UserCynthia Wolberger, Johns Hopkins University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 25 March 2011, 16:15-18:00

MRC LMB Seminar Series

Repeat Proteins:Versatile frameworks for understanding and engineering protein structure and function

UserLynne Regan, Yale University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 21 March 2011, 16:15-18:00

Journal Clubs

Journal Club

UserDaniela (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 21 March 2011, 10:55-11:15

Journal Clubs

Journal Club

UserMay (MH).

HouseSeminar Room, Sanger Building.

ClockMonday 21 March 2011, 10:35-10:55

Journal Clubs

Journal Club

UserKasia (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 21 March 2011, 10:15-10:35

MRC LMB Seminar Series

Non-classical means for regulating small G-proteins

UserShehab Ismail, Max Planck Institute Dortmund.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 17 March 2011, 16:15-18:00

Structural Biology group talks at Biochemistry

"Segmental labelling approaches for multi-domain proteins"

UserBill Broadhurst (RWB group).

HouseSeminar Room, Sanger Building.

ClockTuesday 15 March 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"New dimensions in the study of protein complexes using mass spectrometry"

UserDijana Matak-Vinkovic (Dept. Chemistry).

HouseSeminar Room, Sanger Building.

ClockTuesday 15 March 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"The structural studies of PHD+CXXC domain"

UserBuyu Li (EDL group).

HouseSeminar Room, Sanger Building.

ClockTuesday 08 March 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"Fragment-based drug discovery on the MET receptor"

UserAnja Winter (TLB group).

HouseSeminar Room, Sanger Building.

ClockTuesday 08 March 2011, 16:00-17:00

Centre for Molecular Science Informatics

"Bioactivity Mapping of Chemical Space"

UserDr Jordi Mestres, IMIM, Barcelona Biomedical Reseach Park.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 08 March 2011, 14:15-15:30

Journal Clubs

Journal Club

UserTakashi (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 28 February 2011, 10:55-11:15

Journal Clubs

Journal Club

UserSachin (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 28 February 2011, 10:35-10:55

Journal Clubs

Journal Club

UserAlicia (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 28 February 2011, 10:15-10:35

Centre for Molecular Science Informatics

Neurotransmitter transporters: from ligand-based to systems chemical biology approaches

UserProfessor Olivier Taboureau, Center for Biological Sequence Analysis, Technical University of Denmark.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 22 February 2011, 14:15-15:30

MRC LMB Seminar Series

Accuracy of codon reading by transfer RNAs

UserMΓ₯ns Ehrenberg.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 18 February 2011, 11:30-13:15

MRC LMB Seminar Series

Transport mechanism and membrane interactions of the cation pumps

UserPoul Nissen, Aarhus University, Denmark.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 17 February 2011, 16:15-18:00

MRC LMB Seminar Series

Pre- and postsynaptic NMDA receptors in neocortical synaptic plasticity

UserOle Paulsen, Department of Physiology, University of Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 15 February 2011, 16:15-18:00

MRC LMB Seminar Series

Transcription and R-loops as a source of genome instability

UserAndrΓ©s Aguilera, University of Seville.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 08 February 2011, 16:15-18:00

Centre for Molecular Science Informatics

Toxicity from Predicting Chemistry - Categories, Read-Across and Integrated Testing Strategies

UserProfessor Mark Cronin, Liverpool John Moores University.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 08 February 2011, 14:15-15:30

MRC LMB Seminar Series

In vitro and in vivo single molecule studies of chromosome replication and segregation

UserDavid Sherratt, University of Oxford.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 07 February 2011, 16:15-18:00

MRC LMB Seminar Series

Genetic approaches to understand and manipulate retinal circuit function

UserBotond Roska, Friedrich Miescher Institute for Biomedical Research.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 03 February 2011, 16:15-18:00

Structural Biology group talks at Biochemistry

Super-resolution imaging in pombe

UserDavid Lando (EDL group).

HouseSeminar Room, Sanger Building.

ClockTuesday 01 February 2011, 16:00-17:00

Structural Biology group talks at Biochemistry

"Structural Studies Of Innate Immune Response"

UserEugene Valkov (MH group).

HouseSeminar Room, Sanger Building.

ClockTuesday 01 February 2011, 16:00-17:00

MRC LMB Seminar Series

Off-the-shelf models of chromosomal translocations and using antibody fragments as cancer drug surrogates

UserTerry Rabbitts, Leeds Institute of Molecular Medicine.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 31 January 2011, 16:15-18:00

Journal Clubs

Journal Club

UserSandra (MH).

HouseSeminar Room, Sanger Building.

ClockMonday 31 January 2011, 10:55-11:15

Journal Clubs

Journal Club

UserJarrod (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 31 January 2011, 10:35-10:55

Journal Clubs

Journal Club

UserXue (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 31 January 2011, 10:15-10:35

MRC LMB Seminar Series

Crystal structures of bacterial and yeast ribosomes

UserMarat Yusupov, Illkirch, France.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 27 January 2011, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Drug Protein Interaction Databases

UserAdrian Schreyer, Alicia Higueruelo, Will Pitt.

HouseSeminar Room, Sanger Building.

ClockWednesday 26 January 2011, 10:15-11:00

MRC LMB Seminar Series

Interactions of Cancer Stem Cells with their Niches are Essential for Breast Cancer Metastasis

UserDr Joerg Huelsken, Swiss Federal Univerity of Technology, Lausanne, Switzerland.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 25 January 2011, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The Ghosts of PDBe Past, Present Β and Yet to Come

UserDr Gerard Kleywegt, PDB Europe, EBI, Hinxton.

HouseSeminar Room, Sanger Building.

ClockWednesday 12 January 2011, 10:15-11:00

MRC LMB Seminar Series

The mechanism of retroviral DNA integration through X-ray structures of its key intermediates

UserPeter Cherepanov, Faculty of Medicine, Imperial College.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 11 January 2011, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

i-SITE: An energetic approach to predict ligand-binding site on protein surface

UserDr Mizuki Morita, Laboratory of Bioinformatics, National Institute of Biomedical Innovation (NIBIO), Japan.

HouseSeminar Room, Sanger Building.

ClockMonday 10 January 2011, 11:30-12:00

MRC LMB Seminar Series

Structural biology of bacterial secretion systems

UserGabriel Waksman.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 13 December 2010, 16:15-18:00

MRC LMB Seminar Series

Protein folding homeostasis and prion-like propagation of protein aggregation in neurodegenerative disease

UserRon Kopito, Stanford University, CA USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 10 December 2010, 14:15-16:00

Structural Biology group talks at Biochemistry

Modular Protein Architecture, Cooperativity and Complexity in Cell Regulation

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockFriday 10 December 2010, 12:00-13:00

MRC LMB Seminar Series

Structural insights into the process of co-translational targeting of membrane proteins and translation initiation in eukaryotes

UserNenad Ban.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 06 December 2010, 16:15-18:00

MRC LMB Seminar Series

Femtosecond Membrane-Protein Nanodiffraction using a Hard X-Ray Laser

UserJohn Spence, Arizona State University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 23 November 2010, 16:15-18:00

Centre for Molecular Science Informatics

"Visualising and Predicting Organic Reactivity"

UserDr Scott L Cockroft, Lecturer in Organic Chemistry, University of Edinburgh.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 23 November 2010, 14:15-15:30

MRC LMB Seminar Series

Dehydrated but unharmed? – the mass spectrometry of protein complexes

UserProfessor Carol Robinson, Department of Chemistry, Oxford University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 22 November 2010, 16:15-18:00

Journal Clubs

Journal Club

UserAlicia (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 22 November 2010, 10:55-11:15

Journal Clubs

Journal Club

UserAnja (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 22 November 2010, 10:35-10:55

Journal Clubs

Journal Club

UserZbyszek (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 22 November 2010, 10:15-10:35

MRC LMB Seminar Series

Deconstructin oncogenesis and tumour suppression to find the best cancer drug targets

UserGerard Evan, Department of Biochemistry, Unversity of Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 18 November 2010, 16:15-18:00

Centre for Molecular Science Informatics

β€œAccurate in-silico predictions can halve costs for experimental ADME Tox studies”

UserDr Igor Tetko, Institute for Bioinformatics & Systems Biology, Neuherberg.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 16 November 2010, 14:15-15:15

MRC LMB Seminar Series

Regulation of microRNA biogenesis and function

UserJavier F Caceres, MRC Human Genetics Unit, Edinburgh.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 15 November 2010, 16:15-18:00

MRC LMB Seminar Series

Nucleocytoplasmic Transport Machinery and Pathways: Cell Cycle Regulation and Stress Response

UserNaoko Imamoto, Cellular Dynamics Laboratory, RIKEN ASI.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 15 November 2010, 14:00-16:00

Centre for Molecular Science Informatics

'β€œMulti-Scale Methods for the Investigation of Biological Structures and Processes”

UserProfessor Marcus Elstner, Karlsruhe Institute of Technology.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 09 November 2010, 14:15-15:30

MRC LMB Seminar Series

Mitosis and Meiosis in live mammalian cells: From genome wide RNAi profiling to homologous chromosome segregation

UserJan Ellenberg, EMBL, Heidelberg, Germany.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 05 November 2010, 14:15-16:00

Journal Clubs

Journal Club

UserWill (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 01 November 2010, 10:55-11:15

Journal Clubs

Journal Club

UserMichal (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 01 November 2010, 10:35-10:55

Journal Clubs

Journal Club

UserTim (MH).

HouseSeminar Room, Sanger Building.

ClockMonday 01 November 2010, 10:15-10:35

Centre for Molecular Science Informatics

Exploring chemico-biological interactions using connectivity mapping

UserDr Timothy Gant, MRC Toxicology Unit, University of Leicester.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 26 October 2010, 14:15-15:30

MRC LMB Seminar Series

Ion channels: Structure, modulation, and unconventional approaches

UserDan Minor, University of California, San Francisco, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 25 October 2010, 16:15-18:00

Centre for Molecular Science Informatics

The bacterial outer membrane: capturing the details with molecular dynamics simulations

UserDr Syma Khalid, School of Chemistry, University of Southampton.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 19 October 2010, 14:15-15:30

Centre for Molecular Science Informatics

Application of Informatics within Unilever

UserDr Ian Stott, Informatics & Maths Leader, Unilever R & D, Port Sunlight.

HouseTodd Hamied Room, Dept. of Chemistry.

ClockWednesday 13 October 2010, 14:15-15:30

MRC LMB Seminar Series

Role of intrinsic Flexibility in Protein Regulatory Mechanisms

UserRichard Kriwacki, St Jude's Children's Research Hospital, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 07 October 2010, 16:15-18:00

MRC LMB Seminar Series

Small Molecules and Light as Tools for the Regulation of Biological Proceeses

UserAlex Deiters, North Carolina State University, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 29 September 2010, 16:15-18:00

MRC LMB Seminar Series

Connecting transcription with mRNA processing and chromatin

UserSteve Buratowski Harvard Medical School, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 21 September 2010, 16:15-18:00

Centre for Molecular Science Informatics

Past, present, and future of semiempirical methods

UserDr James J P Stewart, Stewart Computational Chemistry, Colorado Springs, USA.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockThursday 16 September 2010, 14:15-15:30

MRC LMB Seminar Series

Autophagy: molecular machinery and role in diseases

UserTamotsu Yoshimori Osaka University, Japan.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 13 September 2010, 12:15-13:30

MRC LMB Seminar Series

Gene Regulatory Network Guidance of Cellular Identity Choice: Stem Cells to T Cell

UserEllen Rothenberg California Institute of Technology, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 13 September 2010, 11:00-12:00

MRC LMB Seminar Series

Assembly and function of K11-linked ubiquitin chains

UserMichael Rape, University of California, Berkeley, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 08 September 2010, 11:15-13:30

Centre for Molecular Science Informatics

Challenges in rational computer aided enzyme design

UserProfessor Arieh Warshe, University of Southern California.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockThursday 02 September 2010, 14:15-15:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The rational design of small-molecule Neuropilin-1 antagonists

UserTrevor Perrior, Research Director of Domainex.

HouseSeminar Room, Sanger Building.

ClockWednesday 14 July 2010, 10:15-11:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Restraints on Protein Models from NMR Chemical Shifts

UserRinaldo Wander Montalvao (Chemistry, Cambridge)..

HouseSeminar Room, Sanger Building.

ClockWednesday 07 July 2010, 10:35-11:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Software for fragment linking and growing.

UserNikolay Todorov (Molscape).

HouseSeminar Room, Sanger Building.

ClockWednesday 07 July 2010, 10:15-11:00

Journal Clubs

Journal Club

UserAnja (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 05 July 2010, 10:55-11:15

Journal Clubs

Journal Club

UserMarcio (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 05 July 2010, 10:35-10:55

Journal Clubs

Journal Club

UserJawon (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 05 July 2010, 10:15-10:35

Centre for Molecular Science Informatics

In Silico Drug discovery and molecular library focusing

UserProfessor Amiram Goldblum, The Institute of Drug Research, Faculty of Medicine The Hebrew University of Jerusalem.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockWednesday 30 June 2010, 16:00-17:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Using Biacore for fragment screening

UserCatherine McDonnell, GE Healthcare.

HouseSeminar Room, Sanger Building.

ClockWednesday 30 June 2010, 10:15-11:00

Structural Biology group talks at Biochemistry

Molecular recognition of chromatin: crystal structure of the chromatin factor RCC1 in complex with the nucleosome core particle

UserProfessor Song Tan, Penn State University.

HouseLecture theatre, Sanger Building.

ClockTuesday 29 June 2010, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Off-site Targets: Predicting drug polypharmacology using ligand similarity ensembles.

UserMichael Keiser (UCSF).

HouseSeminar Room, Sanger Building.

ClockWednesday 23 June 2010, 10:15-11:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Targetting Protein-Protein Interactions: Synergies between NCEs and New Antibodies.

UserDr Alastair Lawson (UCB- Celltech).

HouseSeminar Room, Sanger Building.

ClockWednesday 16 June 2010, 10:15-11:00

Structural Biology group talks at Biochemistry

TICed off with protein transport into Plasmodium apicoplasts

UserStephanie Glaser (MKH group).

HouseSeminar Room, Sanger Building.

ClockTuesday 15 June 2010, 16:00-17:00

Structural Biology group talks at Biochemistry

Targeting tuberculosis: fragment-based approaces to drug discovery

UserSachin Surade (TLB group).

HouseSeminar Room, Sanger Building.

ClockTuesday 15 June 2010, 16:00-17:00

Journal Clubs

Journal Club

UserLeo (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 14 June 2010, 10:55-11:15

Journal Clubs

Journal Club

UserKasia (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 14 June 2010, 10:35-10:55

Journal Clubs

Journal Club

UserYi-Chun (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 14 June 2010, 10:15-10:35

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Fragment-based drug discovery using X-ray crystallography.

UserDr Anne Cleasby (Astex).

HouseSeminar Room, Sanger Building.

ClockWednesday 02 June 2010, 10:15-11:00

Structural Biology group talks at Biochemistry

RNA processing machinery

UserSteven Hardwick (BL group).

HouseSeminar Room, Sanger Building.

ClockTuesday 01 June 2010, 16:00-17:00

Structural Biology group talks at Biochemistry

Computational Structural Biology in a Pharma

UserWill Pitt (TLB group).

HouseSeminar Room, Sanger Building.

ClockTuesday 01 June 2010, 16:00-17:00

A'-form RNA helices drive microtubule-based mRNA transport in Drosophila

UserPeter Lukavksy, MRC LMB.

HouseLecture theatre, Sanger Building.

ClockFriday 28 May 2010, 11:00-12:00

MRC LMB Seminar Series

The genomic code for nucleosome positioning

UserJon Widom, Department of Biochemistry, Northwestern University, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 20 May 2010, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Can machines understand the Scientific Literature?

UserProfessor Peter Murray Rust (Unilever Centre, Chemistry, Cambridge).

HouseSeminar Room, Sanger Building.

ClockWednesday 19 May 2010, 10:15-11:00

Structural Biology group talks at Biochemistry

Chaperoning histones - structural studies of the H3/H4/RbAp48 complex.

UserMarek Tyl (EDL group).

HouseSeminar Room, Sanger Building.

ClockTuesday 18 May 2010, 16:00-17:00

Structural Biology group talks at Biochemistry

StructuralΒ and evolutionary relationship among epoxide hydrolase in ionophores producing streptomyces

UserMarcio Dias (TLB).

HouseSeminar Room, Sanger Building.

ClockTuesday 18 May 2010, 16:00-17:00

Journal Clubs

Journal Club

UserLeaf (MH).

HouseSeminar Room, Sanger Building.

ClockMonday 17 May 2010, 10:55-11:15

Journal Clubs

Journal Club

UserDima (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 17 May 2010, 10:35-10:55

Journal Clubs

Journal Club

UserTakashi (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 17 May 2010, 10:15-10:35

MRC LMB Seminar Series

The T cells that nature didn't select

UserBent Jakobsen, Immunocore Ltd, Abingdon, Oxon.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 10 May 2010, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Inter-molecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric back-protonation and 2D NOESY

UserDr Ilona Nudelman, Weizmann Institute.

HouseSeminar Room, Sanger Building.

ClockMonday 10 May 2010, 11:15-12:00

MRC LMB Seminar Series

Epigenetic reprogramming in transplanted nuclei

UserJohn Gurdon, Gurdon Institute, University of Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 06 May 2010, 16:15-18:00

Structural Biology group talks at Biochemistry

Solving membrane protein's structure for dummies

UserAntoine Gautier (DN group).

HouseSeminar Room, Sanger Building.

ClockTuesday 04 May 2010, 16:00-17:00

MRC LMB Seminar Series

Gene punctuation: multiple roles of transcriptional termination in regulating eukaryotic gene expression

UserNick Proudfoot, University of Oxford.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 26 April 2010, 16:15-18:00

Structural Biology group talks at Biochemistry

Structural and functional analysis of the interaction between ICAM-1 and DBL domains implicated in cerebral malaria

UserAlan Brown (MKH group).

HouseSeminar Room, Sanger Building.

ClockTuesday 20 April 2010, 16:00-17:00

Structural Biology group talks at Biochemistry

Structural basis for the association of a chromatin remodelling complex with a transcriptional coregulator

UserSara Lejon (EDL group).

HouseSeminar Room, Sanger Building.

ClockTuesday 20 April 2010, 16:00-17:00

Centre for Molecular Science Informatics

"Modelling (skin) lipid bilayers"

UserDr Massimo Noro, Unilever Discover, Port Sunlight.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 20 April 2010, 14:15-15:15

MRC LMB Seminar Series

Some like it hot: nucleosomes mediate temperature sensing

UserPhilip Wigge, John Innes Centre, Norwich.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 01 April 2010, 11:15-13:00

MRC LMB Seminar Series

Unfolding pathways of endoplasmic reticulum stress response and apoptosis in Drosophilia

UserDon Ryoo, New York Univeristy School of Medicine, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 29 March 2010, 11:15-13:00

Structural Biology group talks at Biochemistry

Dissecting the affinity and specificity of ligand for a bipartite ATP-binding site: Structure of the Ligand-bound Pyrococcus furiosus RadA

UserMay Marsh (MH group).

HouseSeminar Room, Sanger Building.

ClockTuesday 23 March 2010, 16:30-17:00

Structural Biology group talks at Biochemistry

Fun with Coiled-coils - the interaction of HR1 domains with Rho family proteins

UserCat Hutchinson (DO group).

HouseSeminar Room, Sanger Building.

ClockTuesday 23 March 2010, 16:00-17:00

MRC LMB Seminar Series

The evolution of long ncRNAs and Prdm9, a special gene

UserChris Pointing, University of Oxford.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 18 March 2010, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Engineering proteins for fragment screening

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockWednesday 17 March 2010, 10:15-11:00

Journal Clubs

Journal Club

UserAlicia (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 15 March 2010, 10:55-11:15

Journal Clubs

Journal Club

UserBen (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 15 March 2010, 10:35-10:55

Journal Clubs

Journal Club

UserAnna (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 15 March 2010, 10:15-10:35

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Surface Plasmon Resonance

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockWednesday 10 March 2010, 10:15-11:00

Research Seminars - Department of Biochemistry 2009/010

Mechanisms that synchronize the Drosophila circadian clock with the environment

UserProf. Ralf Stanewski, Queen Mary College, University of London.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 09 March 2010, 13:00-14:00

Centre for Molecular Science Informatics

"New approaches to virtual screening of molecules and reactions"

UserProfesseur Alexandre Varnek, FacultΓ© de Chimie, UniversitΓ© de Strasbourg,.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockMonday 08 March 2010, 12:00-13:30

Centre for Molecular Science Informatics

"Precise Distance Measurements in Complex Biological Systems"

UserProfessor Garland Marshall, Centre for Computational Biology, Washington University.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockFriday 05 March 2010, 14:00-15:00

Centre for Molecular Science Informatics

"Chemical Biology and Chemogenomics in Drug Discovery"

UserProfessor Hugo Kubinyi, Weisenheim am Sand.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 02 March 2010, 14:15-15:15

Research Seminars - Department of Biochemistry 2009/010

Protein-RNA recognition and dynamics in the regulation of gene expression

UserProf. Michael Sattler, Institute of Structural Biology, Helmholtz Zentrum and Technische UniversitΣ“t, Munich, Germany.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 02 March 2010, 13:00-14:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

STING_DB

User Dr Goran Neshi, Laboratorio de Biologia Computacional, Cidade UniversitΓ‘ria "Zeferino Vaz" , Campinas, Brazil.

HouseSeminar Room, Sanger Building.

ClockWednesday 24 February 2010, 10:15-11:00

Research Seminars - Department of Biochemistry 2009/010

Deconstructing cancer *Alkis-Seraphim Lecture*

Please note that the lecture starts at 5pm

UserProf. Gerard Evan, Department of Biochemistry, University of Cambridge.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 23 February 2010, 17:00-18:00

Research Seminars - Department of Biochemistry 2009/010

Trypanosome glycoproteins and the translation of basic research

UserProf. Mike Ferguson, University of Dundee.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 23 February 2010, 13:00-14:00

Journal Clubs

Journal Club

UserAdrian (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 22 February 2010, 10:55-11:15

Journal Clubs

Journal Club

UserAlan (MKH).

HouseSeminar Room, Sanger Building.

ClockMonday 22 February 2010, 10:35-10:55

Journal Clubs

Journal Club

UserSara (EDL).

HouseSeminar Room, Sanger Building.

ClockMonday 22 February 2010, 10:15-10:35

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Drug-protein Databases: ZINC, Credo,Β CHEMBL

UserWill; Adrian.

HouseSeminar Room, Sanger Building.

ClockWednesday 17 February 2010, 10:15-11:00

Research Seminars - Department of Biochemistry 2009/010

Transport of folded proteins by the bacterial Tat pathway

UserProf. Tracy Palmer, University of Dundee.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 16 February 2010, 13:00-14:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Fragments versus traditional screening . Off-targetΒ analysis

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockWednesday 10 February 2010, 10:15-11:00

Research Seminars - Department of Biochemistry 2009/010

Quorum sensing and the social evolution of bacterial virulence

UserDr. Steven Diggle, University of Nottingham.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 09 February 2010, 13:00-14:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

ITC

UserLeo and Marko.

HouseSeminar Room, Sanger Building.

ClockWednesday 03 February 2010, 10:15-11:00

Research Seminars - Department of Biochemistry 2009/010

Bacterial strategies to build and insert Fe-S clusters into proteins

UserProf. Frederic Barras, University of Marseille, France.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 02 February 2010, 13:00-14:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

X-ray single soaks or cocktails? GrowingΒ versus Linking.Β 

UserRound table (Tom and May to lead), Dave Huggins.

HouseSeminar Room, Sanger Building.

ClockWednesday 27 January 2010, 10:15-11:00

Research Seminars - Department of Biochemistry 2009/010

Influenza, robots and libraries: Understanding the influenza polymerase via directed evolution and structural biology

UserDr. Darren Hart, EMBL Grenoble, France.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 26 January 2010, 13:00-14:00

Journal Clubs

Journal Club

UserFarhana (NG).

HouseSeminar Room, Sanger Building.

ClockMonday 25 January 2010, 10:55-11:15

Journal Clubs

Journal Club

UserBernardo (TLB).

HouseSeminar Room, Sanger Building.

ClockMonday 25 January 2010, 10:35-10:55

Journal Clubs

Journal Club

UserSteven (BL).

HouseSeminar Room, Sanger Building.

ClockMonday 25 January 2010, 10:15-10:35

MRC LMB Seminar Series

TBC

UserVenki Murthy, Dept. of Molecular and Cellular Biology at Harvard University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 21 January 2010, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Targetting PPI

UserAlicia and Narcis Fernandez-Fuentes from the Leeds Institute ofΒ MolecularΒ Medine (LIMM).

HouseSeminar Room, Sanger Building.

ClockWednesday 20 January 2010, 10:15-11:00

Centre for Molecular Science Informatics

Machine like functions at the molecular level

UserProf. Dr. Rainer Herges, Otto-Diels-Institut fΓΌr Organische Chemie, UniversitΓ€t zu Kiel.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 19 January 2010, 14:15-15:15

Research Seminars - Department of Biochemistry 2009/010

Cancelled

UserDr. Oliver Bilker, Sanger Institute.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 19 January 2010, 13:00-14:00

MRC LMB Seminar Series

A Ubiquitin-winnowing machine: Is there ubiquitin chain selection upstream to the proteasome?

UserMichael Glickman, Technion Haifa, Israel.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 14 January 2010, 16:15-18:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Recap of Experimental Fragment-based projects

UserMay, Marko, Anja, Anna, Michal, Sachin, Marcio, Leo, Noha.

HouseSeminar Room, Sanger Building.

ClockWednesday 13 January 2010, 10:15-11:00

Structural Biology group talks at Biochemistry

Mechanism of initiation of DNA synthesis in eukaryotic replication

UserLudovic Sauguet.

HouseSeminar Room, Sanger Building.

ClockTuesday 12 January 2010, 16:00-17:00

Structural Biology group talks at Biochemistry

Thaimine enzyme structure and mechanism

UserXue Yuan Pei.

HouseSeminar Room, Sanger Building.

ClockTuesday 12 January 2010, 16:00-17:00

Research Seminars - Department of Biochemistry 2009/010

Mechanisms of cargo selection in clathrin-coated vesicle formation

UserDr. David Owen, CIMR, University of Cambridge.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 12 January 2010, 13:00-14:00

Structural Biology group talks at Biochemistry

Title to be confirmed

UserDimitri Chirgadze.

HouseSeminar Room, Sanger Building.

ClockTuesday 08 December 2009, 16:00-17:00

Structural Biology group talks at Biochemistry

Title to be confirmed

UserWei Zhang.

HouseSeminar Room, Sanger Building.

ClockTuesday 08 December 2009, 16:00-17:00

Journal Clubs

Journal Club

UserSemin.

HouseSeminar Room, Sanger Building.

ClockMonday 07 December 2009, 10:45-11:00

Journal Clubs

Journal Club

UserAnn.

HouseSeminar Room, Sanger Building.

ClockMonday 07 December 2009, 10:30-10:45

MRC LMB Seminar Series

New genes involved in deafness from large-scale mouse screens

UserKaren Steel.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 03 December 2009, 16:15-18:00

Structural Biology group talks at Biochemistry

Molecular characterisation of human CtIP, a DNA-end resection protein

UserMei Sun.

HouseSeminar Room, Sanger Building.

ClockTuesday 01 December 2009, 16:00-17:00

Structural Biology group talks at Biochemistry

Custom designing E. coli genomic mutations

UserDijun Du.

HouseSeminar Room, Sanger Building.

ClockTuesday 01 December 2009, 16:00-17:00

Research Seminars - Department of Biochemistry 2009/010

An Eye for Stress

UserDr. Christine Slingsby, Birkbeck College, London.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 01 December 2009, 13:00-14:00

MRC LMB Seminar Series

On the origin of RNA and peptide synthesis: clues from biology and prebiotic chemistry

UserJohn D Sutherland, Manchester.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 27 November 2009, 16:15-18:00

Centre for Molecular Science Informatics

"Cheminformatics and Metabolism research and services at the European Bioinformatics Institute"

UserDr Christoph Steinbeck Head,Chemoinformatics & Metabolism, EBI.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 24 November 2009, 14:15-15:15

Research Seminars - Department of Biochemistry 2009/010

Histone demethylation at CpG islands

UserDr. Rob Klose, University of Oxford.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 24 November 2009, 13:00-14:00

Journal Clubs

Journal Club

UserMichal.

HouseSeminar Room, Sanger Building.

ClockMonday 23 November 2009, 10:30-10:45

MRC LMB Seminar Series

Role of PRG-1 (plasticity related gene-1) in glutamatergic transmission

UserDietmar Schmitz, CharitΓ©, Berlin.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 18 November 2009, 16:15-18:00

Structural Biology group talks at Biochemistry

Structure and function of PfEMP1; the sticky protein from Plasmodium falciparum

UserPongsak Khunrae.

HouseSeminar Room, Sanger Building.

ClockTuesday 17 November 2009, 16:00-17:00

Structural Biology group talks at Biochemistry

Title to be confirmed

UserChristian Edlich.

HouseSeminar Room, Sanger Building.

ClockTuesday 17 November 2009, 16:00-17:00

Centre for Molecular Science Informatics

Crawling Across the Web of Chemistry Using ChemSpider

UserDr Antony Williams, VP Strategic Development, ChemSpider, RSC, Wake Forest USA.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 17 November 2009, 14:15-15:15

Research Seminars - Department of Biochemistry 2009/010

Cancer cell invasion in complex environments

UserDr. Erik Sahai, Cancer Research UK, London.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 17 November 2009, 13:00-14:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Completely in vitro protein engineering automation

UserProf Homme Hellinga, Duke University.

HouseLecture theatre, Sanger Building.

ClockMonday 16 November 2009, 16:00-17:00

Journal Clubs

Journal Club

UserMay.

HouseSeminar Room, Sanger Building.

ClockMonday 16 November 2009, 10:30-10:45

MRC LMB Seminar Series

Mass Spectrometry and it's Role in Structural Biology

UserCarol V Robinson.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 10 November 2009, 16:15-16:00

Centre for Molecular Science Informatics

"Adventures with Field Points: virtual screening, scaffold-hopping and beyond"

UserDr Caroline Low, Drug Discovery Centre, ICL.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 10 November 2009, 14:15-15:15

Research Seminars - Department of Biochemistry 2009/010

Structural biology of pilus biogenesis by the chaperone-usher pathway

UserProf. Gabriel Waksman, University College London.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 10 November 2009, 13:00-14:00

Journal Clubs

Journal Club

UserTom M..

HouseSeminar Room, Sanger Building.

ClockMonday 09 November 2009, 10:30-10:45

Structural Biology group talks at Biochemistry

Title to be confirmed

UserMartin Moncrieffe.

HouseSeminar Room, Sanger Building.

ClockTuesday 03 November 2009, 16:00-17:00

Structural Biology group talks at Biochemistry

Crystal diffraction quality: The secret lies in the soak!

UserMonique Gangloff.

HouseSeminar Room, Sanger Building.

ClockTuesday 03 November 2009, 16:00-17:00

Centre for Molecular Science Informatics

We regret that this talk has been cancelled "Structure and function of membrane transporters"

UserProfessor So Iwata, David Blow Chair of Biophysics, Imperial College London.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 03 November 2009, 14:15-15:15

Journal Clubs

Journal Club

UserZbyzsek.

HouseSeminar Room, Sanger Building.

ClockMonday 02 November 2009, 10:30-10:45

Research Seminars - Department of Biochemistry 2009/010

A model for all genomes - the role of transcription factories

UserProf. Peter Cook, University of Oxford.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 27 October 2009, 13:00-14:00

Journal Clubs

Journal Club

UserNick G..

HouseSeminar Room, Sanger Building.

ClockMonday 26 October 2009, 10:30-10:45

Structural Biology group talks at Biochemistry

CARD tricks - magic or mutant?

UserDr Tom Monie.

HouseSeminar Room, Sanger Building.

ClockTuesday 20 October 2009, 16:00-17:00

Structural Biology group talks at Biochemistry

Homo- & Hetero-Dimerisation of TGF-beta superfamily proteins

UserYe Gu.

HouseSeminar Room, Sanger Building.

ClockTuesday 20 October 2009, 16:00-17:00

Research Seminars - Department of Biochemistry 2009/010

The regulation of DNA replication in eukaryotes

UserDr. Philip Zegerman, Gurdon Institute, University of Cambridge.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 20 October 2009, 13:00-14:00

Journal Clubs

Journal Club

UserBen.

HouseSeminar Room, Sanger Building.

ClockMonday 19 October 2009, 10:15-10:30

Journal Clubs

Journal Club

UserRavi.

HouseSeminar Room, Sanger Building.

ClockMonday 19 October 2009, 10:00-10:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Molecular recognition - from single target to protein complexes

UserDr Agata Kranjc Pietrucci from International School of Advanced Studies, Trieste, Italy.

HouseSeminar Room, Sanger Building.

ClockThursday 15 October 2009, 11:00-12:00

Centre for Molecular Science Informatics

"Calculating selectivities in homogeneous catalysis"

UserProfessor Per-Ola Norrby, Department of Chemistry, University of Gothenburg,.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockTuesday 13 October 2009, 14:15-15:15

Research Seminars - Department of Biochemistry 2009/010

Collagen recognition and signalling by the tyrosine kinase DDR1 and DDR2

UserProf. Erhard Hohenester - Imperial College, London.

HouseLecture Theatre, Department of Biochemistry, (Sanger Building).

ClockTuesday 13 October 2009, 13:00-14:00

Journal Clubs

Journal Club

UserMonique.

HouseSeminar Room, Sanger Building.

ClockMonday 12 October 2009, 10:30-10:45

MRC LMB Seminar Series

Mapping metazoan gene regulatory networks to understand transcription factor function in health and disease

UserBart Deplancke, Institute of Bio-engineering, School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL).

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 29 September 2009, 10:30-12:30

Journal Clubs

Journal Club

UserWill.

HouseSeminar Room, Sanger Building.

ClockMonday 28 September 2009, 10:30-10:45

MRC LMB Seminar Series

Cellular quality control of protein aggregates by chaperones

UserBernd Bukau, ZMBH, UniversitΓ€t Heidelberg, Germany.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 25 September 2009, 12:00-14:30

MRC LMB Seminar Series

Neuronal Differentiation and Mechanosensory Transduction in C. elegans.

UserMarty Chalfie, Columbia University, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 24 September 2009, 16:15-17:30

Journal Clubs

Journal Club

UserMaja.

HouseSeminar Room, Sanger Building.

ClockMonday 21 September 2009, 10:30-10:45

MRC LMB Seminar Series

Biochemical Society Early Career Lecture: Structure and specificity of deubiquitinases

UserDavid Komander, LMB.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 14 September 2009, 16:15-17:30

Journal Clubs

Journal Club

UserAnna.

HouseSeminar Room, Sanger Building.

ClockMonday 14 September 2009, 10:30-10:45

MRC LMB Seminar Series

G protein signaling in photoreceptors

UserVadim Arshavsky, Duke University, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 08 September 2009, 16:15-17:30

Journal Clubs

Journal Club

UserCancelled.

HouseSeminar Room, Sanger Building.

ClockMonday 27 July 2009, 10:45-11:00

Journal Clubs

Journal Club

UserAnna.

HouseSeminar Room, Sanger Building.

ClockMonday 27 July 2009, 10:30-10:45

Centre for Molecular Science Informatics

Theoretical and Experimental Studies on Reactions of Organoboranes

UserDr Silvina Pellegrinet (Universidad Nacional de Rosario, Argentina).

HouseRoom U2 02, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockFriday 24 July 2009, 09:00-10:00

Journal Clubs

Journal Club

UserDima.

HouseSeminar Room, Sanger Building.

ClockMonday 20 July 2009, 10:30-10:45

MRC LMB Seminar Series

Genes and Cells that Influence the Lifespan of C. elegans

UserCynthia Kenyon, University of California San Francisco.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 09 July 2009, 16:15-17:30

Journal Clubs

Journal Club

UserMaja.

HouseSeminar Room, Sanger Building.

ClockMonday 06 July 2009, 10:30-10:45

Centre for Molecular Science Informatics

Towards realistic computer modeling of large condensed molecular systems

UserDr Maxim Fedorov (Max Planck Institute, Leipzig).

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Dept. of Chemistry.

ClockWednesday 01 July 2009, 14:15-15:15

Journal Clubs

Journal Club

UserRinaldo.

HouseSeminar Room, Sanger Building.

ClockMonday 29 June 2009, 10:30-10:45

Journal Clubs

Journal Club

UserMartin.

HouseSeminar Room, Sanger Building.

ClockMonday 22 June 2009, 10:30-10:45

Journal Clubs

Journal Club

UserDi-jun.

HouseSeminar Room, Sanger Building.

ClockMonday 15 June 2009, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

HIV-1 Reverse Transcriptase: Structure, Drug Resistance, and Drug Design

UserProfessor Eddy Arnold, Rutgers University.

HouseLecture theatre, Sanger Building.

ClockThursday 11 June 2009, 16:00-17:00

Bioinformatics talks

Piccolo database

UserRichard Bickerton.

HouseSeminar Room, Sanger Building.

ClockMonday 08 June 2009, 10:00-11:00

MRC LMB Seminar Series

How transcription factors deal with nucleosomes

UserMark Ptashne, Memorial Sloan-Kettering Cancer Centre, New York.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 04 June 2009, 16:15-17:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The microseed matrix screening method for protein crystallisation

UserDr May Marsh.

HouseSeminar Room, Sanger Building.

ClockWednesday 03 June 2009, 10:15-11:00

Centre for Molecular Science Informatics

Nanofluidics

UserProfessor Nick Quirke, Nano-bio Physics, University College Dublin.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 26 May 2009, 14:15-15:15

MRC LMB Seminar Series

A Mystery Solved: Why Lis1 ans NudE are important for dynein mediated nuclear migration

UserDr Steven Gross-University of California, Irvine..

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 21 May 2009, 16:15-17:30

Centre for Molecular Science Informatics

Probing the Nature of Asymmetric Hydrogenation of Ketones Catalyzed by Transitional Metal Bifunctional Catalysts

UserProfessor Ming Lei, Beijing University of Chemical Technology.

HouseTodd-Hamied Room, Department of Chemistry.

ClockTuesday 19 May 2009, 09:30-10:30

Journal Clubs

Journal Club

UserChris (TLB group).

HouseSeminar Room, Sanger Building.

ClockMonday 18 May 2009, 10:45-11:00

Journal Clubs

Journal Club

UserSachin.

HouseSeminar Room, Sanger Building.

ClockMonday 18 May 2009, 10:30-10:45

Centre for Molecular Science Informatics

β€œSORD and open access for academics to chemical reaction data”

UserDr Dick Wife, SORD.

HouseRoom U2 02, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockWednesday 13 May 2009, 14:15-15:15

Centre for Molecular Science Informatics

β€œCapturing process: In silico, in laboratorio, and all the messy in-between”

UserDr Cameron Neylon, University of Southampton.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 12 May 2009, 14:15-15:15

Journal Clubs

Journal Club

UserStephanie.

HouseSeminar Room, Sanger Building.

ClockMonday 11 May 2009, 10:30-10:45

Centre for Molecular Science Informatics

β€œNoise and the accurate determination of microbial diversity from pyrosequencing data”

UserDr Christopher Quince, University of Glasgow.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockWednesday 06 May 2009, 12:00-13:00

MRC LMB Seminar Series

Probing dynamic assembly and conformational changes of GPCR signalling complexes using bioluminescence and fluorescence resonance energy transfer approaches.

UserProfessor Michel Bouvier-Institute for Reseach in Immunology and Cancer, UniversitΓ© de MontrΓ©al.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 01 May 2009, 14:30-16:30

MRC LMB Seminar Series

Genetic analysis of Parkinson disease; from fruit flies to moving mitochondria

UserAlex Whitworth-Department of Biomedical Science, The University of Sheffield.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 30 April 2009, 12:00-14:00

Journal Clubs

Journal Club

UserChris (TLB Group).

HouseSeminar Room, Sanger Building.

ClockMonday 27 April 2009, 10:30-10:45

MRC LMB Seminar Series

Nanotubes and Synapses in Immune Cell Biology

UserProfessor Daniel Davis, Imperial College London.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 23 April 2009, 11:00-14:00

Centre for Molecular Science Informatics

"Sense and Non-Sense in Drug Discovery"

UserProfessor Tudor Oprea, University of New Mexico School of Medicine.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockWednesday 22 April 2009, 14:00-15:00

Journal Clubs

Journal Club

UserQian.

HouseSeminar Room, Sanger Building.

ClockMonday 20 April 2009, 10:30-10:45

Journal Clubs

Journal Club

UserVictor (Luisi Group).

HouseSeminar Room, Sanger Building.

ClockMonday 06 April 2009, 10:45-11:00

Journal Clubs

Journal Club

UserJawon.

HouseSeminar Room, Sanger Building.

ClockMonday 06 April 2009, 10:30-10:45

Centre for Molecular Science Informatics

The Baeyer Villiger Reaction: Ionic or Neutral

UserProfessor Nelaine Mora-Diez, Thompson Rivers University.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockThursday 02 April 2009, 11:00-12:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Electrochemically-assisted protein crystallisation: Applications to biosensors

UserProfessor Abel Moreno.

HouseSeminar Room, Sanger Building.

ClockWednesday 01 April 2009, 10:15-11:00

MRC LMB Seminar Series

X-ray tomography generates 3-D views of whole cells at better than 50 nm resolution

UserDr Carolyn Larabell, University of California.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 31 March 2009, 16:15-18:00

Journal Clubs

Journal Club

UserCancelled.

HouseSeminar Room, Sanger Building.

ClockMonday 30 March 2009, 10:30-10:45

MRC LMB Seminar Series

Modern synthetic biology. Darwin from the atom up

UserProfessor Steven A Benner.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 27 March 2009, 16:15-17:30

MRC LMB Seminar Series

The Nature and Chemical Biology of G-quadruplex Nucleic Acids

UserProfessor Shankar Balasubramanian.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 26 March 2009, 16:15-17:30

Journal Clubs

Journal Club

UserSung.

HouseSeminar Room, Sanger Building.

ClockMonday 23 March 2009, 10:30-10:45

Journal Clubs

Journal Club

UserSemin.

HouseSeminar Room, Sanger Building.

ClockMonday 16 March 2009, 10:30-10:45

MRC LMB Seminar Series

Regulators of synapse formation in C. elegans

UserProfessor Kang Shen.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 13 March 2009, 14:00-17:30

MRC LMB Seminar Series

New work with RNase P: regulation in HeLa cells and therapeutic tools

UserProfessor Sidney Altman.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 12 March 2009, 16:15-17:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Public domain medicinal chemistry data at the EBI and the use in drug discovery

UserDr John Overington, Chemogenomics and ChEMBL Databases, European Bioinformatics Institute (EMBL-EBI).

HouseSeminar Room, Sanger Building.

ClockWednesday 11 March 2009, 10:00-11:00

Journal Clubs

Journal Club

UserSid.

HouseSeminar Room, Sanger Building.

ClockMonday 09 March 2009, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The influence of electric and magnetic fields to increase the crystal quality of proteins

UserProfessor Abel Moreno.

HouseSeminar Room, Sanger Building.

ClockWednesday 04 March 2009, 10:15-11:00

Research Seminars - Department of Biochemistry 2008/09

Towards Single Cell Proteomics: Novel Platforms for Protein analysis, including an optical analog of 2D NMR

UserDavid Klug - Imperial College, London.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 03 March 2009, 13:00-14:00

Journal Clubs

Journal Club

UserAdrian.

HouseSeminar Room, Sanger Building.

ClockMonday 02 March 2009, 10:30-10:45

Research Seminars - Department of Biochemistry 2008/09

Alkis Seraphim Lecture - Exploiting the defective wiring of cancer cells for the development of targeted therapies.

Please note the different time

UserJulian Downward - Cancer Research UK.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 24 February 2009, 17:00-18:00

MRC LMB Seminar Series

Activation of Protein Kinases by the HSP90 Molecular Chaperone System

UserDr Laurence Pearl.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 24 February 2009, 16:15-17:30

Journal Clubs

Journal Club

UserBernardo.

HouseSeminar Room, Sanger Building.

ClockMonday 23 February 2009, 10:30-10:45

MRC LMB Seminar Series

From cell mechanics to tissue morphogenesis

UserDr Thomas Lecuit.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 19 February 2009, 16:15-17:30

Research Seminars - Department of Biochemistry 2008/09

Title to be confirmed

UserDavid Owen - CIMR.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 17 February 2009, 13:00-14:00

Journal Clubs

Journal Club

UserMarcio.

HouseSeminar Room, Sanger Building.

ClockMonday 16 February 2009, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The role of impurities in protein crystallisation: advantages and disadvantages

UserProfessor Abel Moreno.

HouseSeminar Room, Sanger Building.

ClockWednesday 11 February 2009, 10:15-11:00

MRC LMB Seminar Series

Disease, development, evolution and environment: insights from eyes

UserProfessor Veronica van Heyningen.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 10 February 2009, 16:15-17:30

Research Seminars - Department of Biochemistry 2008/09

Phenotypes, Faith and Phages: Bacterial Team Building for Attack and Defence.

UserGeorge Salmond - Department of Biochemistry.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 10 February 2009, 13:00-14:00

Journal Clubs

Journal Club

UserAlicia.

HouseSeminar Room, Sanger Building.

ClockMonday 09 February 2009, 10:30-10:45

MRC LMB Seminar Series

Indecent exposure: replication, sex and survival with unprotected telomeres

UserDr Julia Cooper.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 05 February 2009, 16:15-17:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Protein Crystal Growth in Gels and Capillary Tubes

UserProfessor Abel Moreno.

HouseSeminar Room, Sanger Building.

ClockWednesday 04 February 2009, 10:15-11:00

Research Seminars - Department of Biochemistry 2008/09

Wntch (Wnt/Notch) signalling and the homeostatic allocation of cell fates during development

UserAlfonso Martinez-Arias - Department of Genetics.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 03 February 2009, 13:00-14:00

Journal Clubs

Journal Club

UserRicardo.

HouseSeminar Room, Sanger Building.

ClockMonday 02 February 2009, 10:45-11:00

Journal Clubs

Journal Club

UserVictor (Blundell Group).

HouseSeminar Room, Sanger Building.

ClockMonday 02 February 2009, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Conventional and non-conventional methods of protein crystal growth

UserProfessor Abel Moreno.

HouseSeminar Room, Sanger Building.

ClockWednesday 28 January 2009, 10:15-11:00

MRC LMB Seminar Series

Multidimensional proteomics and genetic analysis reveal condensin's function in vertebrate mitotic chromosomes

UserDr Bill Earnshaw.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 27 January 2009, 16:15-17:30

Research Seminars - Department of Biochemistry 2008/09

The bacterial type VI secretion machine: yet another player for protein transport across membranes

UserAlain Filloux - Imperial College, London.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 27 January 2009, 13:00-14:00

MRC LMB Seminar Series

Nuclear architecture in zebrafish: Cajal bodies are required for life and splicing during embryogenesis

UserDr Karla Neugebauer.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 26 January 2009, 16:15-17:30

Journal Clubs

Journal Club

UserTakashi.

HouseSeminar Room, Sanger Building.

ClockMonday 26 January 2009, 10:30-10:45

Research Seminars - Department of Biochemistry 2008/09

Transcriptional silencing by the NuRD co-repressor complex controls lineage commitment in mice

UserBrian.Hendrich (University of Cambridge).

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 20 January 2009, 13:00-14:00

Journal Clubs

Journal Club

UserSara.

HouseSeminar Room, Sanger Building.

ClockMonday 19 January 2009, 10:30-10:45

Research Seminars - Department of Biochemistry 2008/09

Probing the JmjC domain-containing histone demethylase family

UserRob Klose - University of Oxford.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 13 January 2009, 13:00-14:00

Journal Clubs

Journal Club

UserAnna.

HouseSeminar Room, Sanger Building.

ClockMonday 12 January 2009, 10:30-10:45

MRC LMB Seminar Series

IgH Class switching, Translocations, and Lymphoma

UserProfessor Fred Alt.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 15 December 2008, 11:00-12:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Recent adventures in protein folding and design

UserProfessor Lynne Regan, Yale University.

HouseUnilever Lecture Theatre, Department of Chemistry.

ClockMonday 15 December 2008, 11:00-12:00

MRC LMB Seminar Series

DNA sequence dynamics under nucleosome constraint: Form Follows Function Follows Form?

UserProfessor Andrew Fire.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 12 December 2008, 11:15-12:30

MRC LMB Seminar Series

Love at first light

UserProfessor Gero Miesenboeck.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 09 December 2008, 16:15-17:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Leaving drinks for Sheena

UserDr Sheena D'Arcy.

HousePanton Arms pub, Panton Street.

ClockFriday 05 December 2008, 17:30-23:59

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

SPR - theory and practise

UserDr Joe Maman.

HouseMeeting Room A.

ClockThursday 04 December 2008, 13:00-14:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Biocore

UserSpeaker to be confirmed.

HouseLecture Theatre, Department of Biochemistry, Hopkins Building (old building).

ClockWednesday 03 December 2008, 16:00-17:00

Centre for Molecular Science Informatics

Non-covalent interactions: insight into solvation, bio-molecular structure and drug action

UserDr James Platts, Dept. of Chemistry, Cardiff University.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 02 December 2008, 14:15-15:15

Research Seminars - Department of Biochemistry 2008/09

My secret life with Prp45.... by Pol II (the coupling of transcription & splicing)

UserJean Beggs - University of Edinburgh.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 02 December 2008, 13:00-14:00

Journal Clubs

Group Meeting

UserAll Cryst Group.

HouseSeminar Room, Sanger Building.

ClockMonday 01 December 2008, 10:30-10:45

Centre for Molecular Science Informatics

Infinitesimal Rigidity and Graph Clustering across Time-scales: Coarse-graining biomolecular assemblies from the bottom-up

UserDr. Sophia Yaliraki, Dept. of Chemistry, Imperial College London.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 25 November 2008, 14:15-15:15

Research Seminars - Department of Biochemistry 2008/09

Origin and evolution of eukaryotic genomes and organelles

UserMartin Embley - Newcastle University.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 25 November 2008, 13:00-14:00

MRC LMB Seminar Series

Insights into mechanosensitive ion channels

UserProfessor Jim Naismith.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 24 November 2008, 16:15-17:30

Journal Clubs

Journal Club

UserZbyszek.

HouseSeminar Room, Sanger Building.

ClockMonday 24 November 2008, 10:30-10:45

MRC LMB Seminar Series

CANCELLED - Transcriptional regulation by the Polycomb system

TALK CANCELLED DUE TO ILLNESS.

UserDr Juerg Mueller.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 21 November 2008, 16:15-17:30

MRC LMB Seminar Series

Cancerous microRNAs and regulatory binding proteins

UserDr Reuven Agami.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 20 November 2008, 16:15-17:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Expression systems for protein complexes

User Dr Imre Berger, EMBL, Heidelberg.

HouseLecture Theatre, Department of Biochemistry, Hopkins Building (old building).

ClockWednesday 19 November 2008, 16:00-17:00

Centre for Molecular Science Informatics

Molecular flexibility and recognition in proteins and nucleic acids

UserDr. Charles Laughton, School of Pharmacy, The University of Nottingham.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 18 November 2008, 14:15-15:15

Research Seminars - Department of Biochemistry 2008/09

How can we adapt DNA microarray technology to measure proteins?

UserFridjof Lund Johansen - University of Oslo, Norway.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 18 November 2008, 13:00-14:00

Journal Clubs

Journal Club

UserBen.

HouseSeminar Room, Sanger Building.

ClockMonday 17 November 2008, 10:45-11:00

Journal Clubs

Journal Club

UserAnn.

HouseSeminar Room, Sanger Building.

ClockMonday 17 November 2008, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Pathway-based analysis of genome-wide siRNA screens

UserDr. Miguel Camargo, Merck, Boston USA.

HouseSeminar Room, Sanger Building.

ClockWednesday 12 November 2008, 10:15-11:00

Journal Clubs

Journal Club

UserTom M..

HouseSeminar Room, Sanger Building.

ClockMonday 10 November 2008, 10:30-10:45

Journal Clubs

Journal Club

UserVivien.

HouseSeminar Room, Sanger Building.

ClockMonday 10 November 2008, 10:15-10:30

Journal Clubs

Journal Club

UserNoha.

HouseSeminar Room, Sanger Building.

ClockMonday 10 November 2008, 10:00-10:15

MRC LMB Seminar Series

Thinking Small: Fragment-Based Drug Design

UserDr Glyn Williams.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 06 November 2008, 16:15-17:30

MRC LMB Seminar Series

Identification of 20 novel breast cancer fusion genes using genome-wide massively parallel paired-end sequencing

Talk preceded by free tea and plaque presentation in the MPLT foyer at 3.45 pm

UserDr Philip Stephens.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 04 November 2008, 16:15-17:30

Centre for Molecular Science Informatics

Predicting Molecular Properties: the Role of Data Visualisation and Feature Selection

UserProf. Ian Nabney, Neural Computing Research Group, School of Engineering and Applied Science, Aston University.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 04 November 2008, 14:15-15:15

Research Seminars - Department of Biochemistry 2008/09

Thermostabilisation and structure determination of a b1-adrenergic receptor

UserChris Tate - MRC LMB.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 04 November 2008, 13:00-14:00

Journal Clubs

Journal Club

UserMaya.

HouseSeminar Room, Sanger Building.

ClockMonday 03 November 2008, 10:45-11:00

Research Seminars - Department of Biochemistry 2008/09

Protein structure determination from NMR chemical shifts

UserMichele Vendruscolo - Department of Chemistry.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 28 October 2008, 13:00-14:00

Journal Clubs

Journal Club

UserSemin.

HouseSeminar Room, Sanger Building.

ClockMonday 27 October 2008, 10:45-11:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Party for Richard and Timo

UserAll welcome!.

HouseSeminar Room, Sanger Building.

ClockFriday 24 October 2008, 15:00-16:00

Research Seminars - Department of Biochemistry 2008/09

The inhibitory glycine receptor: Routes to a structure - pathology relationship

UserCord-Michael Becker - UniversitΓ€t Erlangen-NΓΌrnberg, Germany.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 21 October 2008, 13:00-14:00

Journal Clubs

Journal Club

UserNick G..

HouseSeminar Room, Sanger Building.

ClockMonday 20 October 2008, 10:45-11:00

Centre for Molecular Science Informatics

Protein Structure Bioinformatics as One Tool to Improve Human Health

UserProf. Gert Vriend, Nijmegen Centre for Molecular Life Sciences.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 14 October 2008, 14:15-15:15

Research Seminars - Department of Biochemistry 2008/09

Aberrant Rho GTPase activation and signaling in cancer development

UserChanning Der - University of North Carolina at Chapel Hill, NC.

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 14 October 2008, 13:00-14:00

Journal Clubs

Journal Club

UserMartin.

HouseSeminar Room, Sanger Building.

ClockMonday 13 October 2008, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Fragment-based Screening and It's Role in Ontario Cancer Institute

UserProf Nickolay Chirgadze, Department of Pharmacology and Toxicology, University of Toronto.

HouseSeminar Room, Sanger Building ?.

ClockSunday 12 October 2008, 11:15-12:00

MRC LMB Seminar Series

Tackling an old enemy: new ways to target RNA

UserDr Gabriele Varani.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 10 October 2008, 14:30-15:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Molecular Puzzles: Learning About Function and Mechanism of Enzymes From their Structures

UserDr. Alex Wlodawer, Macromolecular Crystallography Laboratory, National Cancer Institute Frederick.

HouseSeminar Room, Sanger Building.

ClockFriday 10 October 2008, 13:00-14:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Convergence of Molecular Epidemiology, Functional Biology and Host-pathogen Interactions: Zeroing on Potential Drug Targets for M. TUBERCULOSIS

UserProfessor Seyed E. Hasnain, Vice-Chancellor University of Hyderabad.

HouseSeminar Room, Sanger Building.

ClockWednesday 08 October 2008, 11:00-12:00

Research Seminars - Department of Biochemistry 2008/09

Species specific transcription in mice carrying a human chromosome

UserDuncan Odom (Cancer Research UK, CRI).

HouseLecture Theatre, Biochemistry, Department of (Sanger Building).

ClockTuesday 07 October 2008, 13:00-14:00

MRC LMB Seminar Series

eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA

UserDr Leos Valasek.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 06 October 2008, 16:15-17:30

Journal Clubs

Group Meeting - Cancelled

UserAll Cryst Group.

HouseSeminar Room, Sanger Building.

ClockMonday 06 October 2008, 10:30-10:45

Journal Clubs

Journal Club

UserNo Journal Club (2nd Year PhD Poster Session).

HouseVenue to be confirmed.

ClockSunday 28 September 2008, 10:30-10:45

Centre for Molecular Science Informatics

Representation and predictive modeling of complex biomolecular datasets

UserProf. Alexander Tropsha, School of Pharmacy, The University of North Carolina at Chapel Hill.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockFriday 26 September 2008, 14:00-15:00

MRC LMB Seminar Series

SNAREs, Synaptotagmin, and Fusion Pores

UserProfessor Meyer Jackson.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 25 September 2008, 16:15-17:30

MRC LMB Seminar Series

The structure of tubulin and the control of microtubule assembly

UserProfessor Marcell Knossow.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 16 September 2008, 16:15-17:30

Journal Clubs

Journal Club

UserMonique.

HouseSeminar Room, Sanger Building.

ClockFriday 12 September 2008, 10:30-10:45

MRC LMB Seminar Series

Connectomics in the developing nervous system

UserProfessor Jeff W Lichtman.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 22 August 2008, 11:15-12:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

test

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockThursday 14 August 2008, 10:30-11:30

Journal Clubs

Journal club

UserAdrian.

HouseSeminar Room, Sanger Building.

ClockMonday 28 July 2008, 10:45-11:00

Journal Clubs

Journal club

UserMaya.

HouseSeminar Room, Sanger Building.

ClockMonday 28 July 2008, 10:30-10:45

Journal Clubs

Journal club

UserAlicia.

HouseSeminar Room, Sanger Building.

ClockMonday 21 July 2008, 10:45-11:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Neurotrophic factors in Drosophila

UserDr Alicia Hidalgo, University of Birmingham.

HouseSeminar Room, Sanger Building.

ClockFriday 18 July 2008, 10:30-11:30

Journal Clubs

Journal club

UserWi.

HouseSeminar Room, Sanger Building.

ClockMonday 14 July 2008, 10:45-11:00

Journal Clubs

Journal club

UserVictor.

HouseSeminar Room, Sanger Building.

ClockMonday 14 July 2008, 10:30-10:45

MRC LMB Seminar Series

Novel molecular switches for optical research on living cells

UserDr Gerard Marriott.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 10 July 2008, 16:15-17:30

Leaving Party for Julia, Tammy and Jessica

UserJulia, Tammy and Jessica.

HouseSeminar Room, Sanger Building.

ClockWednesday 09 July 2008, 16:30-17:30

Journal Clubs

Journal club

UserSteven.

HouseSeminar Room, Sanger Building.

ClockMonday 07 July 2008, 10:45-11:00

Journal Clubs

Journal club

UserPongsak.

HouseSeminar Room, Sanger Building.

ClockMonday 07 July 2008, 10:30-10:45

MRC LMB Seminar Series

Understanding and controlling cell death

UserProfessor Jim Wells.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 04 July 2008, 16:15-17:30

Journal Clubs

Journal club

UserRichard.

HouseSeminar Room, Sanger Building.

ClockMonday 30 June 2008, 10:45-11:00

Journal Clubs

Journal club

UserSung.

HouseSeminar Room, Sanger Building.

ClockMonday 30 June 2008, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Small hydrogen-bonded motifs in proteins and their significance for amyloid formation

UserJames Milner-White, University of Glasgow.

HouseSeminar Room, Sanger Building.

ClockThursday 26 June 2008, 11:30-12:30

MRC LMB Seminar Series

Structural analysis of cells and viruses at molecular resolution with 3D electron microscopy

UserDr Sriram Subramaniam.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 25 June 2008, 16:15-17:30

Journal Clubs

Journal club

UserJawon.

HouseSeminar Room, Sanger Building.

ClockMonday 23 June 2008, 10:45-11:00

Journal Clubs

Journal club

UserDijun.

HouseSeminar Room, Sanger Building.

ClockMonday 23 June 2008, 10:30-10:45

Journal Clubs

Journal club

UserMarko.

HouseSeminar Room, Sanger Building.

ClockMonday 16 June 2008, 10:45-11:00

Journal Clubs

Journal club

UserRinaldo.

HouseSeminar Room, Sanger Building.

ClockMonday 16 June 2008, 10:30-10:45

Centre for Molecular Science Informatics

Molecular Informatics for Drug Discovery

UserProf. Jacob de Vlieg, Organon.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 10 June 2008, 14:15-15:15

MRC LMB Seminar Series

Function of diverse transcriptional coactivators in animal cells

UserProfessor Robert G Roeder.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 09 June 2008, 16:15-17:30

Journal Clubs

Journal club

UserSemin.

HouseSeminar Room, Sanger Building.

ClockMonday 09 June 2008, 10:30-10:45

Centre for Molecular Science Informatics

Protein structure bioinformatics as one tool to improve human health

UserProf. Gert Vriend, Nijmegen Centre for Molecular Life Sciences.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 03 June 2008, 14:15-15:15

Journal Clubs

Journal club

UserSachin.

HouseSeminar Room, Sanger Building.

ClockMonday 02 June 2008, 10:30-10:45

Journal Clubs

Journal club

UserTom M..

HouseSeminar Room, Sanger Building.

ClockMonday 19 May 2008, 10:45-11:00

Journal Clubs

Journal club

UserAnjum.

HouseSeminar Room, Sanger Building.

ClockMonday 19 May 2008, 10:30-10:45

Centre for Molecular Science Informatics

Quantum and classical partition functions of water from computer simulation

UserDr. Richard Henchman, School of Chemistry, University of Manchester.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockFriday 16 May 2008, 15:00-16:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structural chemistry in the pharmaceutical industry: view from a returned exile

UserDr Nic Harmer, University of Exeter.

HouseMeeting Room B, Sanger Building.

ClockMonday 12 May 2008, 13:00-14:00

Journal Clubs

Journal club

UserNoha.

HouseSeminar Room, Sanger Building.

ClockMonday 12 May 2008, 10:45-11:00

Journal Clubs

Journal club

UserTakashi.

HouseSeminar Room, Sanger Building.

ClockMonday 12 May 2008, 10:30-10:45

MRC LMB Seminar Series

Transcription factories and nuclear organization of the genome

UserDr Peter Fraser.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 06 May 2008, 16:15-17:30

MRC LMB Seminar Series

A "molecular sled" activates the adenovirus proteinase and carries it along tens of thousands of base pairs of viral DNA via one-dimensional diffusion to locate its substrates

UserDr Walter Mangel.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 01 May 2008, 16:15-17:30

Centre for Molecular Science Informatics

Developing Quantum Topological Molecular Similarity (QTMS)

UserDr. Paul Popelier, School of Chemistry, University of Manchester.

HouseWolfson Lecture Theatre, Department of Chemistry.

ClockTuesday 29 April 2008, 14:15-15:15

Journal Clubs

Journal club

UserAdrian.

HouseSeminar Room, Sanger Building.

ClockMonday 28 April 2008, 10:45-11:00

Journal Clubs

Journal club

UserStephannie.

HouseSeminar Room, Sanger Building.

ClockMonday 28 April 2008, 10:30-10:45

MRC LMB Seminar Series

The interplay between phosphorylation and polyubiquitinatioan in regulating the innate immune system

UserProfessor Sir Philip Cohen.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 24 April 2008, 16:15-17:30

Journal Clubs

Journal club

UserLeaf.

HouseSeminar Room, Sanger Building.

ClockMonday 21 April 2008, 10:45-11:00

Journal Clubs

Journal club

UserChris.

HouseSeminar Room, Sanger Building.

ClockMonday 21 April 2008, 10:30-10:45

Centre for Molecular Science Informatics

Using Ontology to Classify Members of a Protein Family

UserDr. Robert Stevens, School of Computer Science, University of Manchester.

HouseTodd-Hamied Room, Department of Chemistry.

ClockMonday 14 April 2008, 14:15-15:15

Journal Clubs

Journal club

UserRicardo.

HouseSeminar Room, Sanger Building.

ClockMonday 14 April 2008, 10:45-11:00

Journal Clubs

Journal club

UserYi-chun.

HouseSeminar Room, Sanger Building.

ClockMonday 14 April 2008, 10:30-10:45

MRC LMB Seminar Series

Using microfluidics to ask other peoples questions in biology

UserDr Mark Tracey.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 11 April 2008, 16:15-17:30

MRC LMB Seminar Series

The organization and topology of the bacterial nucleoid: steps towards a holistic theory of transcriptional regulation

UserProfessor Georgi Muskhelishvili.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 10 April 2008, 16:15-17:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

DNA site-specific recombination: Architecture of a recombinase

UserProfessor Marshall Stark University of Glasgow.

HouseSeminar Room, Sanger Building.

ClockWednesday 09 April 2008, 12:00-13:00

MRC LMB Seminar Series

Using Chemical Tools to Elucidate the Molecular Mechanism of Malaria Infection and Develop a Malaria Vaccine

UserProfessor Peter Seeberger.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 08 April 2008, 10:30-11:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Mechanisms of Transmembrane Transport: towards structures of membrane protein drug targets

UserProfessor Robert Stroud, University of California, San Francisco.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockMonday 07 April 2008, 13:00-14:00

Journal Clubs

Journal club

UserGugu.

HouseSeminar Room, Sanger Building.

ClockMonday 07 April 2008, 10:45-11:00

Journal Clubs

Journal club

UserQian.

HouseSeminar Room, Sanger Building.

ClockMonday 07 April 2008, 10:30-10:45

MRC LMB Seminar Series

A glimpse into the atomic structure of plant photosystem I - 3.5 billion years of perfection

UserProfessor Nathan Nelson.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 03 April 2008, 16:15-17:30

Journal Clubs

Journal club

UserBernardo.

HouseSeminar Room, Sanger Building.

ClockMonday 31 March 2008, 10:45-11:00

Journal Clubs

Journal club

UserMatthias.

HouseSeminar Room, Sanger Building.

ClockMonday 31 March 2008, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Toll like receptors - Investigating innate immunity and infection

UserDr Kathy Triantafilou, Infection and immunity Group, University of Sussex.

HouseSeminar Room, Sanger Building.

ClockFriday 28 March 2008, 10:30-11:30

Bioinformatics talks

Party for Catherine

UserCatherine Worth.

HouseSeminar Room, Sanger Building.

ClockThursday 27 March 2008, 17:00-18:00

MRC LMB Seminar Series

Targeting the lipid kinases

UserDr Zachary Knight.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 18 March 2008, 16:15-17:30

Journal Clubs

Journal club

UserMartin.

HouseSeminar Room, Sanger Building.

ClockMonday 17 March 2008, 10:45-11:00

Journal Clubs

Journal club

UserDima.

HouseSeminar Room, Sanger Building.

ClockMonday 17 March 2008, 10:30-10:45

MRC LMB Seminar Series

Structure and Dynamics of the Human beta 2 Adrenergic Receptor

UserProfessor brian Kobilka.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 14 March 2008, 14:15-15:30

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

High intrinsic binding specificity mediates the interactions of a yeast SH3 domain

UserDr. Elliott Stollar, Program in Molecular Structure and Function, Hospital for Sick Children, Toronto.

HouseSeminar Room, Sanger Building.

ClockFriday 14 March 2008, 12:00-13:00

Centre for Molecular Science Informatics

Translating Chemogenomics into Medicinal Benefit

UserProf. Andrew Hopkins, College of Life Sciences, University of Dundee.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 11 March 2008, 14:15-15:15

Journal Clubs

Journal club

UserNick G..

HouseSeminar Room, Sanger Building.

ClockMonday 10 March 2008, 10:45-11:00

Journal Clubs

Journal club

UserZbyszek.

HouseSeminar Room, Sanger Building.

ClockMonday 10 March 2008, 10:30-10:45

MRC LMB Seminar Series

How do miRNAs silence gene expression?

UserDr Elisa Izaurralde, Department of Biochemistry, Max-Planck-Institute for Developmental Biology.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 07 March 2008, 14:15-15:30

MRC LMB Seminar Series

Centrosomal delivery of secretory granules

UserProf Gillian Griffiths, Cambridge Institute for Medical Research.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 06 March 2008, 16:15-17:30

Bioinformatics talks

Models from NMR data

UserDr Tim Stevens.

HouseSeminar Room, Sanger Building.

ClockWednesday 05 March 2008, 10:00-11:00

Centre for Molecular Science Informatics

Protein folding - going in the right direction

UserDr. Charlotte Deane, Dept. of Statistics, University of Oxford.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 04 March 2008, 14:15-15:15

Biochemistry Tea Club

Optimising expression of mammalian proteins for interaction studies.

UserMike Dyson Cell Interaction Group Department of Biochemistry University of Cambridge.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 04 March 2008, 13:00-14:00

Journal Clubs

Journal club

UserJulia.

HouseSeminar Room, Sanger Building.

ClockMonday 03 March 2008, 10:45-11:00

Journal Clubs

Journal club

UserTimo.

HouseSeminar Room, Sanger Building.

ClockMonday 03 March 2008, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Expriences in Structure-based Discovery

UserProf Rod Hubbard, Vernalis and University of York.

HouseSeminar Room, Sanger Building.

ClockMonday 03 March 2008, 09:00-10:00

MRC LMB Seminar Series

Autophagy and neurodegenerative diseases

UserProf David Rubinsztein, Cambridge Institute for Medical Research.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 28 February 2008, 16:15-17:30

Biochemistry Tea Club

Tight regulation of intrinsically unstructured proteins: from transcript synthesis to protein degradation.

UserMadan Babu, MRC Laboratory of Molecular Biology University of Cambridge.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 26 February 2008, 13:00-14:00

MRC LMB Seminar Series

RNA catalysis: sophisticated biochemistry by a simple biopolymer

UserDr Adrian Ferre D'Amare, Fred Hutchinson Cancer Research Center, Seattle.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 25 February 2008, 16:15-17:30

Journal Clubs

Journal club

UserSid.

HouseSeminar Room, Sanger Building.

ClockMonday 25 February 2008, 10:45-11:00

Journal Clubs

Journal club

UserMonique.

HouseSeminar Room, Sanger Building.

ClockMonday 25 February 2008, 10:30-10:45

Journal Clubs

Journal club

UserMarcio.

HouseSeminar Room, Sanger Building.

ClockMonday 25 February 2008, 10:00-10:15

Centre for Molecular Science Informatics

Analysis of Antibody Sequence and Structure

UserDr. Andrew Martin, Dept. of Biochemistry and Molecular Biology, University College London.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 19 February 2008, 14:15-15:15

Biochemistry Tea Club

Hormonal control of shoot branching.

UserOttoline Leyser Department of Biology University of York.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 19 February 2008, 13:00-14:00

Biochemistry Tea Club

Why tumour suppressors suppress and oncogenes onc?

UserProfessor Gerard Evan, Cancer Research Institute & Department of Cellular & Molecular Pharmacology, University of California, San Francisco.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockMonday 18 February 2008, 11:30-12:30

Journal Clubs

Journal club

UserBen.

HouseSeminar Room, Sanger Building.

ClockMonday 18 February 2008, 10:30-10:45

Biochemistry Tea Club

Alkis Seraphim Lecture: "A molecular basis of proteolysis and its regulation"

UserRobert Huber, Max-Planck-Institut fuer Biochemie Martinsried Germany.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 12 February 2008, 17:00-18:00

Centre for Molecular Science Informatics

QM to QSAR

UserProf. Jonathan Hirst, School of Chemistry, University of Nottingham.

HouseUnilever Lecture Theatre, Unilever Centre for Molecular Informatics, Department of Chemist.

ClockTuesday 12 February 2008, 14:15-15:15

Journal Clubs

Journal club

UserSachin.

HouseSeminar Room, Sanger Building.

ClockMonday 11 February 2008, 10:45-11:00

Journal Clubs

Journal club

UserAlicia.

HouseSeminar Room, Sanger Building.

ClockMonday 11 February 2008, 10:30-10:45

MRC LMB Seminar Series

Towards in vivo molecular automata

UserDr Yaakov Benenson, Bauer Fellow, FAS Center for Systems Biology, Harvad University.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 07 February 2008, 16:15-17:30

Biochemistry Tea Club

The natural history of biological networks: Evolution at the system level.

UserMichael P.H. Stumpf Division of Molecular Biosciences Centre for BioinformaticsΒ Β Β  Imperial College LondonΒ .

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 05 February 2008, 13:00-14:00

MRC LMB Seminar Series

Feldberg Foundation Prize Lecture: "Formation of ribonucleoprotein particles and their nuclear export through nuclear pore complexes

UserDr Ed Hurt, University of Heidelberg.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 31 January 2008, 16:15-17:30

Bioinformatics talks

Virtual screening and ultrafast shape recognition

UserDr Pedro Ballester, Department of Chemistry, Oxford University.

HouseSeminar Room, Sanger Building.

ClockWednesday 30 January 2008, 10:00-11:00

Biochemistry Tea Club

Excitability of aggressive cancer cells: Role of voltage-gated sodium channel expression.

UserMustafa Djamgoz, Professor of Cancer Biology Imperial College London.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 29 January 2008, 13:00-14:00

Journal Clubs

Journal club

UserAlicia.

HouseSeminar Room, Sanger Building.

ClockMonday 28 January 2008, 10:45-11:00

Journal Clubs

Journal club

UserWi.

HouseSeminar Room, Sanger Building.

ClockMonday 28 January 2008, 10:30-10:45

Journal Clubs

Journal club

UserAlan.

HouseSeminar Room, Sanger Building.

ClockMonday 21 January 2008, 10:45-11:00

Journal Clubs

Journal club

UserVictor.

HouseSeminar Room, Sanger Building.

ClockMonday 21 January 2008, 10:30-10:45

Journal Clubs

Journal club

UserSteven.

HouseSeminar Room, Sanger Building.

ClockMonday 14 January 2008, 10:45-11:00

Journal Clubs

Journal club

UserSungsam Gong.

HouseSeminar Room, Sanger Building.

ClockMonday 14 January 2008, 10:30-10:45

Journal Clubs

Journal club

UserRichard.

HouseSeminar Room, Sanger Building.

ClockMonday 07 January 2008, 10:45-11:00

Journal Clubs

Journal club

UserPongsak.

HouseSeminar Room, Sanger Building.

ClockMonday 07 January 2008, 10:30-10:45

MRC LMB Seminar Series

Turning LMB Science into a Half a Billion Dollar Business

UserDr Ian Tomlinson.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 13 December 2007, 16:15-17:30

MRC LMB Seminar Series

ENCODE: Understanding our genome

UserDr Ewan Birney.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 11 December 2007, 16:15-17:30

Journal Clubs

Journal club

UserMatthew.

HouseSeminar Room, Sanger Building.

ClockWednesday 05 December 2007, 10:45-11:00

Journal Clubs

Journal club

UserRinaldo.

HouseSeminar Room, Sanger Building.

ClockWednesday 05 December 2007, 10:30-10:45

Biochemistry Tea Club

Expanding antibiotic diversity by multienzyme engineering: from models to medicines

UserProf. Peter Leadlay.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 04 December 2007, 13:00-14:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Fragment based drug discovery - from crystal to clinic

UserDr David Rees, Astex Therapeutics.

HouseSeminar Room, Sanger Building.

ClockMonday 03 December 2007, 09:00-10:00

Biochemistry Tea Club

Control of Pseudomonas aeruginosa infections by means of quorum sensing blockage

UserProf. Mike Givskov, BioScience and Technology BioCentrum Technical University of Denmark.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 27 November 2007, 13:00-14:00

Journal Clubs

Journal club

UserMarko.

HouseSeminar Room, Sanger Building.

ClockMonday 26 November 2007, 10:45-11:00

Journal Clubs

Journal club

UserAdrian.

HouseSeminar Room, Sanger Building.

ClockMonday 26 November 2007, 10:30-10:45

MRC LMB Seminar Series

Microfluidics in Biology

UserDr Ronny van't Oever.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 23 November 2007, 16:15-17:30

MRC LMB Seminar Series

The DNA damage problem and its impact on cancer and aging

UserDr Jan Hoeijmakers.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 20 November 2007, 16:15-17:30

Journal Clubs

Journal club

UserLeonardo.

HouseSeminar Room, Sanger Building.

ClockMonday 19 November 2007, 10:45-11:00

Journal Clubs

Journal club

UserJawon.

HouseSeminar Room, Sanger Building.

ClockMonday 19 November 2007, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Paradoxical Features of Nicotinic Receptor

UserProfessor Stuart Edelstein, University of Geneva.

HouseSeminar Room, Sanger Building.

ClockWednesday 14 November 2007, 12:00-13:00

MRC LMB Seminar Series

Organisation of membrane transport by microtubule motors and plus tracking proteins

UserDr Anna Akhmanova.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 13 November 2007, 16:15-17:30

Biochemistry Tea Club

Phosphorylation and ubiquitination site analysis by mass spectrometry

UserDr Nick Morrice, MRC Protein Phosphorylation Unit University of Dundee.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 13 November 2007, 13:00-14:00

Journal Clubs

Journal club

UserLeonardo.

HouseSeminar Room, Sanger Building.

ClockMonday 12 November 2007, 10:45-11:00

Journal Clubs

Journal club

UserTakashi.

HouseSeminar Room, Sanger Building.

ClockMonday 12 November 2007, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

New protein purification columns and media from GE Healthcare

UserPenny Hamlyn, GE Healthcare.

HouseSeminar Room, Sanger Building.

ClockThursday 08 November 2007, 11:00-12:00

MRC LMB Seminar Series

RNA Structure, Catalysis and the Origin of Lfe

UserDr Bill Scott.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 06 November 2007, 16:15-17:30

Biochemistry Tea Club

Activating Rac - Roles and regulation of the P-Rex family

UserDr Heidi Welch, Inositide Laboratory The Babraham Institute.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 06 November 2007, 13:00-14:00

Journal Clubs

Journal club

UserNoha.

HouseSeminar Room, Sanger Building.

ClockMonday 05 November 2007, 10:15-10:30

Journal Clubs

Journal club

UserSemin.

HouseSeminar Room, Sanger Building.

ClockMonday 05 November 2007, 10:00-10:15

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

UCB Approaches to Drug Discovery, A Focus on 2 Cambridge projects

UserDr Will Pitt, UCB Celltech.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockMonday 05 November 2007, 09:00-10:00

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

Structural basis of fatty acid synthesis catalyzed by giant multienzyme complexes

UserDr Nenad Ban, Professor of Structural Molecular Biology, ETH Zurich, Swiss Federal Institute of Technology.

HouseSeminar Room, Sanger Building.

ClockFriday 02 November 2007, 14:15-15:15

MRC LMB Seminar Series

Structural basis of interative fatty acid synthesis catalyzed by giant multienzyme complexes

UserDr Nenad Ban.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 01 November 2007, 16:15-17:30

MRC LMB Seminar Series

Silence of the Genes: DNA methylation in cancer

UserDr Howard Cedar.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 01 November 2007, 11:15-12:30

Biochemistry Tea Club

Cancer metabolism: from the molecule to the patient

UserProf. John Griffiths, Cancer Research UK Cambridge Research Institute.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 30 October 2007, 13:00-14:00

Journal Clubs

Journal club

UserTom M..

HouseSeminar Room, Sanger Building.

ClockMonday 29 October 2007, 10:45-11:00

Journal Clubs

Journal club

UserAnjum.

HouseSeminar Room, Sanger Building.

ClockMonday 29 October 2007, 10:30-10:45

MRC LMB Seminar Series

Genomics: From Humans to the Environment

UserDr Craig Venter.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 26 October 2007, 11:00-12:30

Journal Clubs

Journal club

UserDeepti.

HouseSeminar Room, Sanger Building.

ClockMonday 22 October 2007, 10:45-11:00

Journal Clubs

Journal club

UserBernardo.

HouseSeminar Room, Sanger Building.

ClockMonday 22 October 2007, 10:30-10:45

Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

The long and the short: virulence proteins from Staphylococcus and Streptococcus

UserProfessor Ted Baker, Director, Centre for Molecular Biodiscovery.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockFriday 19 October 2007, 15:00-16:00

Biochemistry Tea Club

Gatekeepers of pluripotency

UserProf. Austin Smith, Wellcome Trust Centre for Stem Cell Research.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 16 October 2007, 13:00-14:00

Journal Clubs

Journal club

UserMartin.

HouseSeminar Room, Sanger Building.

ClockMonday 15 October 2007, 10:45-11:00

Journal Clubs

Journal club

UserNick F..

HouseSeminar Room, Sanger Building.

ClockMonday 15 October 2007, 10:30-10:45

Journal Clubs

Journal Club

UserAnn.

HouseSeminar Room, Sanger Building.

ClockMonday 08 October 2007, 10:45-11:00

Journal Clubs

Journal Club

UserNick G..

HouseSeminar Room, Sanger Building.

ClockMonday 08 October 2007, 10:30-10:45

Journal Clubs

Journal Club

UserMaya.

HouseSeminar Room, Sanger Building.

ClockWednesday 03 October 2007, 10:00-11:00

MRC LMB Seminar Series

Regulation of the proteasome and the dynamics of multiubiquitin chains

UserProf Dan Finley, Dept. of Cell Biology, Harvard Medical School, Boston, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockFriday 21 September 2007, 12:00-13:30

MRC LMB Seminar Series

What structural studies tell us about amyloids and prions

UserProfessor David Eisenberg, HHMI?UCLA-DOE Institute for Genomics and Proteomics, Los Angeles, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 04 September 2007, 16:15-17:30

MRC LMB Seminar Series

Searching for biological function and evolutionary trajectories in the protein universer

UserDr L Aravind, National Center for Biotechnology Information, NIH, USA.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 08 August 2007, 16:15-17:30

MRC LMB Seminar Series

HIV assembly - is it the plasma membrane after all?

UserMark Marsh, MRC LMCB.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 03 July 2007, 16:15-17:30

MRC LMB Seminar Series

Organising Microtubules in Space and Time

UserDamien Brunner, EMBL Heidelberg.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 19 June 2007, 16:15-17:30

MRC LMB Seminar Series

Evolution of the Pathological process underlying sporadic Parkinson's Disease

UserHeiko Braak, University of Frankfurt.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockMonday 04 June 2007, 16:15-17:30

MRC LMB Seminar Series

Mechanisms of epigenetic reprogramming in mammalian development

UserWolf Reik, Babraham Institute, Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 31 May 2007, 16:15-17:30

MRC LMB Seminar Series

Structural Analysis of Glutamate receptor gating and allosteric regulation

UserMark Mayer, NIH, Bethesda.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 22 May 2007, 16:15-17:30

MRC LMB Seminar Series

Centrosomes: organizers of cell division in C.elegans embryos

UserTony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 17 May 2007, 16:15-17:30

MRC LMB Seminar Series

Optogenetic control of neuronal function, and molecular analysis of nicotinic acetylcholine receptor associated proteins in Caenorhabditis elegens

UserAlex Gottschalk, Universit of Frankfurt.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 16 May 2007, 16:15-17:30

MRC LMB Seminar Series

Neural Processing of Optic Flow in the Fly

UserAlex Borst, MPI of Neurobiology, Martinsried.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 10 May 2007, 16:15-17:30

MRC LMB Seminar Series

LepA, one of the most conserved proteins known and present in all bacteria and mitochondriae, is a ribosomal elongation factor with a new function

UserKnud Nierhaus, Max Planck Institute for Molecular Genetics, Berlin.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 24 April 2007, 16:15-17:30

MRC LMB Seminar Series

The molecular mechanics of eukaryotic translation initiation

UserJon Lorsch, John Hopkins, Baltimore.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 12 April 2007, 16:15-17:30

MRC LMB Seminar Series

Ubiquitin signalling networks

UserIvan Dikic, Goethe University Medical School, Frankfurt.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 29 March 2007, 16:15-17:30

MRC LMB Seminar Series

Receptor-recruitment by a natively disordered protein

UserColin Kleanthous, University of York.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockWednesday 21 March 2007, 14:15-15:30

MRC LMB Seminar Series

Quantitative proteomics of organelles of the early secretory pathway

UserJohn Bergeron, McGill University, Montreal, Canada.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockTuesday 13 March 2007, 16:15-17:30

MRC LMB Seminar Series

Structural variation in the human genome

UserMatthew Hurles, Wellcome Trust Sanger Institute, Cambridge.

HouseMax Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

ClockThursday 08 March 2007, 16:15-17:30

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Rothschild Public Lecture | Forty years of causal inference: Report of a great-grandfather Morning Break Cooperation as a Laboratory of Being Cambridge RNA Club - IN PERSON Ice-core timescales and the synchronization of paleoclimate archives Director's Briefing
 

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